PDGF CC Human
目录号 : GP20821Platelet Derived Growth Factor-CC Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 97.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. | Shipping Condition | Shipped at Room temp. |
| Synonyms | Platelet Derived Growth Factor C; Spinal Cord-Derived Growth Factor; FALLOTEIN; PDGF-C; VEGF-E; SCDGF; Secretory Growth Factor-Like Protein; Platelet-Derived Growth Factor C; PDGFC. | ||
| Amino Acid Sequence | MHHHHHHVVD LNLLTEEVRL YSCTPRNFSV SIREELKRTD TIFWPGCLLV KRCGGNCACC LHNCNECQCV PSKVTKKYHE VLQLRPKTGV RGLHKSLTDV ALEHHEECDC VCRGSTGG. | ||
| Solubility | It is recommended to reconstitute the lyophilized PDGF-CC in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. | ||
| Stability | Lyophilized PDGF-CC although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution PDGF-CC should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. | ||
| Biological Activity | The ED50, as measured in a proliferation assay using mouse NR6R-3T3 cells, is less than 350ng/ml. | ||
| Formulation | Lyophilized from a 0.2µm filtered solution in Acetonitrile and TFA. | ||
Platelet Derived Growth Factor-CC (PDGF-CC) belongs to the PGDF family of growth factors. PDGF-CC binds with high-affinity to PDGF R-a and activates PDGF R-ab heterodimers. During development, PDGF-CC is involved in ductal morphogenesis, cardiovascular smooth muscle cell proliferation; also PDGF-CC is an angiogenic factor. Furthermore, PDGF-CC is expressed in numerous tumors and tumor cell lines, and may be linked with tumorigenesis.
The ED50, as measured in a proliferation assay using mouse NR6R-3T3 cells, is less than 350ng/ml.
Lyophilized PDGF-CC although stable at room temperature for 3 weeks, should be stored desiccated below -18°C . Upon reconstitution PDGF-CC should be stored at 4°C between 2-7 days and for future use below -18°C .For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.