Pentylone-d3 (hydrochloride) (CRM)
目录号 : GC91550Pentylone-d3 (hydrochloride) (CRM) is intended for use as an internal standard for the quantification of pentylone .
Cas No.:1781649-12-4
Sample solution is provided at 25 µL, 10mM.
Quality Control & SDS
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Pentylone-d3 (hydrochloride) (CRM) is intended for use as an internal standard for the quantification of pentylone .[1] It has been detected in products sold as bath salts.[2] Pentylone is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.
References:
[1].Tang, Y., Xu, L., Zhao, J., et al.Metabolism of dipentylone in zebrafish and human liver microsomes determined by liquid chromatography-high resolution mass spectrometryJ. Pharm. Biomed. Anal.236115710(2023).
[2].Marinetti, L.J., and Antonides, H.M.Analysis of synthetic cathinones commonly found in bath salts in human performance and postmortem toxicology: Method development, drug distribution and interpretation of resultsJ. Anal. Toxicol.37(3)135-146(2013).
制备储备液 | |||
1 mg | 5 mg | 10 mg | |
1 mM | 3.639 mL | 18.1951 mL | 36.3901 mL |
5 mM | 0.7278 mL | 3.639 mL | 7.278 mL |
10 mM | 0.3639 mL | 1.8195 mL | 3.639 mL |
第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量) | ||||||||||
给药剂量 | mg/kg | 动物平均体重 | g | 每只动物给药体积 | ul | 动物数量 | 只 | |||
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方) | ||||||||||
% DMSO % % Tween 80 % saline | ||||||||||
计算重置 |
计算结果:
工作液浓度: mg/ml;
DMSO母液配制方法: mg 药物溶于 μL DMSO溶液(母液浓度 mg/mL,
体内配方配制方法:取 μL DMSO母液,加入 μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入 μL saline,混匀澄清。
1. 首先保证母液是澄清的;
2.
一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。