Peptides(肽)

Cat.No. 产品名称 Information

GA21462 FITC-εAhx-Amyloid β-Protein (1-42)

GA21461 FITC-β-Ala-Amyloid β-Protein (1-42)

GA21460 FITC-β-Ala-Amyloid β-Protein (1-40)

GA21424 ent-Amyloid β-Protein (1-42) All-D Aβ (1-42) exhibits similar properites as the all-L Aβ. The peptide forms ion channels in lipid bilayers.

GA21423 ent-[Amyloid β-Protein (20-16)]-β-Ala-D-Lys(ent-[Amyloid β-Protein (16-20)]) This all-D peptide contains two retro-inverso peptide klvff motifs of KLVFF (H-3682) corresponding to amino acids 16 to 20 of amyloid β-protein. The tandem dimer retro-inverso peptide showed about a 100-fold higher binding affinity (Kd = 1.3 . 10?² µM) for amyloid β-protein (1-40) fibrils than KLVFF (Kd = 1.1 ± 0.3 µM). It was also found to be more effective in preventing ordered fibril formation than the parent peptide KLVFF as judged by its increased ability to inhibit thioflavin T binding to β-sheet structures.

GA21407 Dynorphin A (1-8) Dynorphin A (1-8) 是在胎盘组织提取物中发现的主要阿片肽。

GA21397 Dolastatin 15

DLS 15

A peptide with anticancer activity

GA21360 DABCYL-γ-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS DABCYL-γ-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS 是人肾素的底物。

GA21353 Cys-Gly-Lys-Lys-Gly-Amyloid β-Protein (35-40)

GA21352 Cys-Gly-Lys-Arg-Amyloid β-Protein (1-42)

GA21351 Cys-Gly-His-Gly-Asn-Lys-Ser-Amyloid β-Protein (33-40) CGHGNKSGLMVGGVV.

GA21319 Cyclo(-Gln-Gly)

环(GLY-GLN)

Cyclo(-Gln-Gly) 是一种环状二肽。

GA21296 Cyclo(-Ala-Glu) Cyclo(-Ala-Glu) 是一种环状二肽。

GA21285 C-Peptide 2 (rat) C-Peptide 2 (rat)，31-氨基酸肽，是胰岛素原的一种成分。

GA21105 Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH Boc-Phe-D-Leu-Phe-D-Leu-Phe-OH ({Boc}-FLFLF) 是一种甲酰肽受体 (FPR) 家族拮抗剂，可优先抑制通过甲酰肽受体触发的活性。

GA21044 Boc-Leu-Gly-Arg-AMC Boc-Leu-Gly-Arg-AMC 是转化酶的荧光 AMC 底物。

GA21037 Boc-Ile-Glu-Gly-Arg-AMC

IEGR-AMC

Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) 是一种活化因子 X (FXa) 特异性荧光肽底物，用于因子 VIII 测定。

GA20865 BNP-45 (mouse)

BNP-45, mouse

BNP-45 (mouse) (BNP-45, mouse) 是一种循环形式的小鼠脑利钠肽，从小鼠心脏中分离出来，具有有效的降血压和利钠作用。

GA20855 Biotinyl-εAhx-Amyloid β-Protein (1-42) The flexible LC spacer increases the accessibility of the biotin moiety.

GA20854 Biotinyl-εAhx-Amyloid β-Protein (1-40) The flexible LC spacer increases the accessibility of the biotin moiety.

GA20847 Biotinyl-Substance P Biotinyl-Substance P 是生物素标记的 Substance P。

GA20828 Biotinyl-Atrial Natriuretic Factor (1-28) (human) Biotinyl-Atrial Natriuretic Factor (1-28) (human) 是三种哺乳动物利钠肽 (NPs) 之一，对体液稳态和血压具有内分泌作用。

GA20824 Biotinyl-Amyloid β-Protein (1-42) N-terminally biotin-labeled Aβ42.

GA20823 Biotinyl-Amyloid β-Protein (1-40)

生物素淀粉样蛋白肽(1-40)

Biotinyl-Amyloid β-Protein (1-40) 是一种 N 端标记的生物素化淀粉样蛋白 ß-(1-40) 肽。

GA20808 Big Endothelin-1 (1-39), porcine Big Endothelin-1 (1-39)，猪是 endothelin-1 的前体。

GA20807 Big Endothelin-1 (1-38), human

大内皮素-1 (1-38)，人

A peptide precursor of endothelin-1

GA20780 Arg-Glu(EDANS)-(Asn⁶⁷⁰,Leu⁶⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (668-675)-Lys(DABCYL)-Arg Fluorogenic (FRET) substrate for pro-memapsin-2 containing the β-secretase site EVNLDAEF of the Swedish mutation of APP. The kinetic parameters at pH 4.5 are Km = 5.4 µM and kcat = 0.24 min?¹.

GA20776 Apelin-12 (human, bovine, mouse, rat) Apelin-12（人、牛、小鼠、大鼠）是多肽中最有效的 C 末端片段之一，对孤儿受体 APJ 受体具有高亲和力。

GA20760 Angiotensin A (1-7) 血管紧张素 A (1-7) 是肾素-血管紧张素系统 (RAS) 的成员，是一种血管活性肽，是 G 蛋白偶联受体 MrgD 的内源性配体。

GA20756 Amyloid β-Protein (6-20)

GA20755 Amyloid β-Protein (5-42) Abeta 5-42 is produced from amyloid precursor protein by action of caspases. It is deposited in Alzheimer's disease brain as well, but less prone to aggregation.

GA20754 Amyloid β-Protein (4-42)

Β-淀粉样蛋白(4-42)

Aβ 4-42 could be one of the earliest and most prominent Aβ species deposited in AD brain. Sequencing of amyloid plaque cores showed that 64% of the isolated Aβ had a phenylalanine at its N-terminus, and indeed, IP/MS experiments identified Aβ 4-42 as a major Aβ species in AD patients. Additionally, Aβ 4-42 was found to be a component of cotton wool plaques in familial AD patients with the V261I PS1 mutation. Aβ 4-42 was discovered as well in amyloid deposits from vascular dementia and familial Danish dementia patients. These observations indicate that Aβ 4-42 may contribute to the development of multiple CNS diseases.

GA20753 Amyloid β-Protein (40-1) Inactive control

GA20752 Amyloid β-Protein (40-1) Reverse sequence of Aβ 1-40.

GA20751 Amyloid β-Protein (37-39)

甘氨酰-甘氨酰-L-缬氨酸

GA20750 Amyloid β-Protein (36-38)

GA20749 Amyloid β-Protein (35-25) Aβ 25-35 的反向序列，非活性对照。

GA20748 Amyloid β-Protein (3-42) The N-terminally truncated Aβ42 may be formed in increased amounts as AD progresses. Aβ 3-42 is the precursor of the Pyr-peptide. (Pyr³)-Aβ 3-42 positive plaques are resistant to age-dependent degradation likely due to their high stability and propensity to aggregate.

GA20747 Amyloid β-Protein (3-40)

GA20746 Amyloid β-Protein (33-42) GLMVGGVVIA, a partial sequence of β-amyloid protein which is used for raising antibodies against Aβ 1-42. Li et al. studied the aggregation behavior of this and other Aβ 1-42 C-terminal fragments.

GA20745 Amyloid β-Protein (25-35) amide 淀粉样蛋白 β-蛋白 (25-35) 的酰胺化导致一种产物，其中淀粉样蛋白 β-蛋白 (25-35) 的淀粉样蛋白生成能力已大大降低，而神经毒性活性被发现与聚集状态无关肽。

GA20744 Amyloid β-Protein (2-42) Aβ 2-42 could be a biomarker for differentiating AD from other degenerative dementias, such as frontotemporal dementias (FTD). The peptide promotes phagocytosis by macrophages.

GA20743 Amyloid β-Protein (20-29) FAEDVGSNKG.

GA20742 Amyloid β-Protein (17-40) Cleavage of APP by alpha- and gamma-secretase (i.e. the non-amyloidogenic pathway) yields p3 peptide, a mix of Aβ 17-40 and Aβ 17-42. p3 is a major constituent of diffuse plaques observed in AD brains and pre-amyloid plaques in people affected by Down syndrome.

GA20741 Amyloid β-Protein (16-22) Self-assembling Aβ sequence.

GA20740 Amyloid β-Protein (16-20) KLVFF 对应于结合全长淀粉样蛋白的最小序列 β；蛋白质。五肽充当 β-sheet breaker。

GA20739 Amyloid β-Protein (1-6) amide Experiments using sub-peptides of Aβ42 revealed that the epitope identified by the antibody A8, as described by Ying and coworkers, lies within the 1-6 region of Aβ. The antibody displays high affinity for soluble Aβ42 oligomers in the molecular weight range of 16.5-25 kDa, and detected target antigen in brain sections from senescence-accelerated SAMP 8 mice. Amidated or acetylated and amidated forms of the sequence were used for example for quantitative structure retention relationships (QSRR) experiments. The latter could allow prediction of reversed-phase high-performance liquid chromatography (HPLC) retention of peptides, as reported by Kaliszan and coworkers.

GA20738 Amyloid β-Protein (1-6) Experiments using sub-peptides of Aβ42 revealed that the epitope identified by the antibody A8, as described by Ying and coworkers, lies within the 1-6 region of Aβ. The antibody displays high affinity for soluble Aβ42 oligomers in the molecular weight range of 16.5-25 kDa, and detected target antigen in brain sections from senescence-accelerated SAMP 8 mice.

GA20737 Amyloid β-Protein (1-46) Precursor of the secreted amyloid β-protein (1-40) and (1-42). The identification of amyloid-β-protein (1-46) led to the identification of a zeta-cleavage site between the known γ- and ε-cleavage sites within the transmembrane domain of amyloid-β precursor protein (APP).

GA20736 Amyloid β-Protein (1-43)

淀粉Β-蛋白(1-43)

淀粉样蛋白 β-Protein (1-43) 比久负盛名的 Aβ1-42 更容易聚集并具有更高的毒性。