PICK1 Human
目录号 : GP22582Protein Interacting With PRKCA 1 Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 85.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | ProteinInteracting With PRKCA 1; PRKCABP; Protein Kinase C-Alpha-Binding Protein; ProteinInteracting With C Kinase 1; Protein Kinase C; Alpha Binding Protein; ProteinInteracting With PRKCA; PRKCA-Binding Protein; PICK; PRKCA-binding protein. | ||
| Amino Acid Sequence | MGSSHHHHHHSSGLVPRGSH MGSMFADLDYDIEEDKLGIP TVPGKVTLQK DAQNLIGISI GGGAQYCPCL YIVQVFDNTP AALDGTVAAG DEITGVNGRSIKGKTKVEVA KMIQEVKGEV TIHYNKLQAD PKQGMSLDIV LKKVKHRLVE NMSSGTADAL GLSRAILCNDGLVKRLEELE RTAELYKGMT EHTKNLLRAF YELSQTHRAF GDVFSVIGVR EPQPAASEAF VKFADAHRSIEKFGIRLLKT IKPMLTDLNT YLNKAIPDTR LTIKKYLDVK FEYLSYCLKV KEMDDEEYSC IALGEPLYRVSTGNYEYRLI LRCRQEARAR FSQMRKDVLE KMELLDQKHV QDIVFQLQRL VSTMSKYYND CYAVLRDADVFPIEVDLAHT TLAYGLNQEE FTDGEEEEEE EDTAAGEPSR DTRGAAGPLD KGGSWCDS. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | PICK1 protein solution (0.25mg/ml) containing Phosphatebuffered saline (pH7.4), 30% glycerol and 1mM DTT. | ||
Protein Interacting with PRKCA 1, also known as PICK1 includes a PDZdomain, through which it interacts with protein kinase C, alpha (PRKCA). PICK1performs as an adaptor which binds to and arranges the subcellular localizationof various membrane proteins. PICK1 interacts with multiple glutamate receptorsubtypes, monoamine plasma membrane transporters, in addition to non-voltagegated sodium channels, and might target PRKCA to these membrane proteins and thereforeregulates their distribution as well as function. PICK1 has also been found to performas an anchoring protein which particularly targets PRKCA to mitochondria ina ligand-specific manner.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.