PPP2R1A Human
目录号 : GP22146Protein Phosphatase 2, Regulatory Subunit A Alpha Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 90.0% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | PPP2R1A;Protein Phosphatase 2; Regulatory Subunit A; Alpha; Protein Phosphatase 2(Formerly 2A); Regulatory Subunit A (PR 65); Alpha Isoform; PP2A Subunit AIsoform PR65-Alpha; PP2A Subunit A Isoform R1-Alpha; Serine/Threonine ProteinPhosphatase 2A; 65 KDa Regulatory Subunit A; Alpha Isoform; Serine/Threonine-ProteinPhosphatase 2A; 65 KDa Regulatory Subunit A Alpha Isoform; Protein Phosphatase2 (Formerly 2A); Regulatory Subunit A; Alpha Isoform; Medium TumorAntigen-Associated 61 KDA Protein; Medium Tumor Antigen-Associated 61 KDaProtein; 65kDa Regulatory Subunit A; Protein Phosphatase 2A; ProteinPhosphatase 2; Regulatory Subunit A; Alpha Isoform; PP2A-Aalpha; PP2AAALPHA; PR65A. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMAAADGD DSLYPIAVLI DELRNEDVQL RLNSIKKLST IALALGVERT RSELLPFLTD TIYDEDEVLL ALAEQLGTFT TLVGGPEYVH CLLPPLESLA TVEETVVRDK AVESLRAISH EHSPSDLEAH FVPLVKRLAG GDWFTSRTSA CGLFSVCYPR VSSAVKAELR QYFRNLCSDD TPMVRRAAAS KLGEFAKVLE LDNVKSEIIP MFSNLASDEQ DSVRLLAVEA CVNIAQLLPQ EDLEALVMPT LRQAAEDKSW RVRYMVADKF TELQKAVGPE ITKTDLVPAF QNLMKDCEAE VRAAASHKVK EFCENLSADC RENVIMSQIL PCIKELVSDA | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | PPP2R1A protein solution (1mg/ml) containing PhosphateBuffered Saline (pH7.4) and 10% glycerol. | ||
Protein Phosphatase 2, Regulatory Subunit AAlpha, also known as PPP2R1A is part of the PPP family of phosphatases,which regulates a diversity of vital cellular processes. PPP2R1A subunit, PR65,functions as a scaffolding molecule which coordinates the assembly of thecatalytic subunit and a variable regulatory B subunit. PPP2R1A is essential forproper chromosome segregation as well as for centromeric localization of SGOL1in mitosis. Furthermore, PPP2R1A phosphorylation is an in vivo mechanism whichregulates the PP2A signaling complex as well as increasing the PP2A activity inheart failure.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.