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Proctolin Sale

(Synonyms: 直肠肽) 目录号 : GC31177

Proctolin是一种内源性五肽,用作兴奋性神经调节剂。

Proctolin Chemical Structure

Cas No.:57966-42-4

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1mg
¥360.00
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5mg
¥900.00
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10mg
¥1,440.00
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25mg
¥2,592.00
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50mg
¥3,960.00
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Sample solution is provided at 25 µL, 10mM.

Description

Proctolin is an endogenous pentapeptide that acts as an excitatory neuromodulator.

Proctolin can increase the frequency of action potentials, increase the amplitude of muscle contraction, and initiate activity in quiescent systems[1]. In the arthropods, Proctolin acts as a neuromodulator and possibly as a neurohormone. It does not appear to function as a conventional neurotransmitter[2]. Proctolin is a pentapeptide with the mature peptide of RYLPT, and it is the first insect neuropeptide to be sequenced and chemically characterized. The first identification of a Proctolin precursor gene is CG7105 in D. melanogaster. Although a previous study showed that Proctolin is absent in B. mori, this pentapeptide is recently identified in a proteomic analysis of B. mori wings. However, the Bombyx Proctolin gene does not produce a mature peptide because cleavage sites are not present at the N-terminal and C-terminal of the RYLPT sequence, and a similar gene is observed in C. suppressalis. Therefore, a true Proctolin has been considered to be not observed in B. mori and C. suppressalis[3].

[1]. McGrath LL, et al. De novo transcriptome assembly for the lobster Homarus americanus and characterization of differential gene expression across nervous system tissues. BMC Genomics. 2016 Jan 16;17:63. [2]. Orchard I, et al. Proctolin: a review with emphasis on insects. J Neurobiol. 1989 Jul;20(5):470-96. [3]. Xu G, et al. Identification and expression profiles of neuropeptides and their G protein-coupled receptors in the rice stem borer Chilo suppressalis. Sci Rep. 2016 Jun 29;6:28976.

化学性质

Cas No. 57966-42-4 SDF
别名 直肠肽
Canonical SMILES Arg-Tyr-Leu-Pro-Thr
分子式 C30H48N8O8 分子量 648.75
溶解度 H2O : 100 mg/mL (154.14 mM; Need ultrasonic) 储存条件 Store at -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 1.5414 mL 7.7071 mL 15.4143 mL
5 mM 0.3083 mL 1.5414 mL 3.0829 mL
10 mM 0.1541 mL 0.7707 mL 1.5414 mL
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