PRTN3 Human
目录号 : GP22171Proteinase-3 Human
Sample solution is provided at 25 µL, 10mM.
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PRTN3 is a natural antigen having a molecular mass of 25kDa to 32kDa due to glycosylation isoforms. PRTN3 is isolated from human peripheral blood leukocytes.
| Purity | Greater than 80% in the sum of different glycosylation isoforms according to following sectionas determined by SDS-PAGE and capillary electrophoresis. | Source | Native. |
| Phycical Appearance | Shipping Condition | Shipped with Ice Packs. | |
| Synonyms | AGP7; P29; PR-3; ACPA; C-ANCA; MBT; MBN; Leukocyte proteinase 3; Neutrophil proteinase 4; Wegener granulomatosis autoantigen; Azurophil granule protein 7; myeloblastin; Serine proteinase neutrophil. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles. | ||
| Formulation | PRTN3 is supplied in 16mM HEPES buffer pH-8.0, 400mM NaCl, and 20% glycerol. | ||
PRTN3 is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema once managed by tracheal insufflation to hamsters.
Western blot with rabbit anti-PR3 antisera andmouse anti-PR3 monoclonal antibodies.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles.