Cat.No. 产品名称 Information

GC27451 (R)-3-(Trifluoromethyl)-6,6a,7,8,9,10-hexahydropyrazino[1,2-d]pyrido[3,2-b][1,4]oxazine

(R)-3-(三氟甲基)-6,6a,7,8,9,10-六氢吡嗪并[1,2-d]吡啶并[3,2-b][1,4]噁嗪

GC26366 PD-1/PD-L1-IN-33

PD-1/PD-L1-IN-33 (Compound N11) 是一种 PD-1/PD-L1 抑制剂。PD-1/PD-L1-IN-33 抑制 PD-1 和 PD-L1 相互作用，IC50 为 6.3 nM。PD-1/PD-L1-IN-33 促进 T 细胞增殖、激活和浸润到肿瘤球中。PD-1/PD-L1-IN-33 具有免疫调节和抗癌活性。

GC27450 tert-Butyl 2-nitro-4-(piperazin-1-yl)benzoate

2-硝基-4-(哌嗪-1-基)苯甲酸叔丁酯

GC27448 Ethyl 4-oxo-6-phenoxy-3,4-dihydrophthalazine-1-carboxylate

4-氧代-6-苯氧基-3,4-二氢酞嗪-1-甲酸乙酯

GC27449 Methyl 3-(3-hydroxyphenyl)-2-thiophenecarboxylate

3-(3-羟基苯基)-2-噻吩甲酸甲酯

GC27443 3-(6,8-Dimethylimidazo[1,2-a]pyrazin-2-yl)-7-fluoro-2H-chromen-2-one

3-(6,8-二甲基咪唑并[1,2-a]吡嗪-2-基)-7-氟-2H-色烯-2-酮

GC27447 4-((3,5-Bis(2-cyanopropan-2-yl)phenyl)amino)-2-chloropyrimidine-5-carboxamide

4-((3,5-双(2-氰基丙-2-基)苯基)氨基)-2-氯嘧啶-5-甲酰胺

GC33486 Dehydronitrosonisoldipine

尼索地平杂质3

A calcium channel antagonist

GC15359 SL-327 Selective MEK1/2 inhibitor

GC27446 1-(Benzo[d][1,3]dioxol-5-yl)-2-(6-methylpyridin-2-yl)ethan-1-one

1-(苯并[d][1,3]二羟基-5-基)-2-(6-甲基吡啶-2-基)乙烷-1-酮

GD53181 4-Hydroxyphenylacetaldehyde

GC27445 Methyl 6-chloro-2'-methyl-6'-oxo-1',4',5',6'-tetrahydro-[3,4'-bipyridine]-3'-carboxylate

6-氯-2'-甲基-6'-氧代-1',4',5',6'-四氢-[3,4'-联吡啶]-3'-羧酸甲酯

GC27444 6-bromo-N-(3-fluorobenzyl)pyridin-2-amine

6-溴-N-(3-氟苄基)吡啶-2-胺; 2-Pyridinamine, 6-bromo-N-[(3-fluorophenyl)methyl]-

GP10161 Proteinase K A broad-spectrum serine protease

GC40196 Levetiracetam-d6

左乙拉西坦杂质-d6,UCB L059-d6

An internal standard for the quantification of levetiracetam

GC12581 K145 SphK2 inhibitor

GC68840 Cbl-b-IN-3 Cbl-b-IN-3 (Compound 23) 是 casitas B 系淋巴瘤原癌基因-b (Cbl-b) 抑制剂， IC50 为 < 1 nM。 Cbl-b 是一种 E3 泛素连接酶，负调控 T 细胞活化。

GC18350 Cytochrome C (from horse)

细胞血素C; 细胞色素丙

GC27442 BMS-986397

BMS-986397 是基于 cereblon 的酪蛋白激酶 1α (CK1α) 分子胶降解剂，可导致 TP53 野生型 AML (急性髓性白血病) 细胞快速凋亡 (apoptosis) 和细胞周期停滞。

GC27441 BMS-986470

BMS-986470 是一种能够激活胎儿血红蛋白（HbF）的 CRBN E3 泛素连接酶调节剂（CELMoD）。

GC11703 Moclobemide (Ro 111163)

吗氯贝胺; Ro111163

Reversible inhibitor of MAO-A

GC52457 WRW4 (trifluoroacetate salt)

Trp-Arg-Trp-Trp-Trp-Trp-CONH2, Trp-Arg-Trp-Trp-Trp-Trp-NH2, WRWWWW-NH2

A peptide antagonist of FPR2 and FPR3

GC32854 Digitonin

洋地黄皂苷

Digitonin is a steroidal saponin used extensively as a mild non-ionic detergent.

GC11908 Cisplatin

顺铂; cis-Platinum; CDDP; cis-Diaminodichloroplatinum

Cisplatin is one of the best and first metal-based chemotherapeutic drugs, which is used for wide range of solid cancers such as testicular, ovarian, bladder, lung, cervical, head and neck cancer, gastric cancer and some other cancers.

GN10023 Isorhamnetin

异鼠李素; 3'-Methylquercetin

Red turnip,goldenrod,mustard leaf,ginkgo biloba.

GC18485 Retro-2

RN 1-001

A selective inhibitor of retrograde protein trafficking mediated by syntaxin-5

GP26001 COX-2 Protein, Human (sf9, His)

Prostaglandin G/H synthase 2; COX-2; PGHS-2

PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS).

GC27440 BMS-986463

BMS-986463 是一种 WEE1 kinase 分子胶降解剂、是 CRBN E3 连接酶调节剂 (CELMoD)。

GC32387 Farnesol

法呢醇

An isoprenoid with diverse biological activities

GC19979 MPP hydrochloride MPP hydrochloride is a potent and selective ER (estrogen receptor) modulator.

GC47018 Cacodylic Acid (sodium salt hydrate)

二甲砷酸钠三水合物

A reagent used in electron microscopy techniques

GP10071 BNP (1-32), human

醋酸奈西立肽,H2N-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys-Lys-Val-Leu-Arg-Arg-His-OH

Brain natriuretic peptide

GC31353 Glutathione oxidized (L-Glutathione oxidized)

氧化型谷胱甘肽; L-Glutathione oxidized; GSSG; Oxiglutatione

Glutathioneoxidized是通过氧化谷胱甘肽产生的，谷胱甘肽是细胞内一种主要的抗氧化剂和解毒剂。

GC30715 Guanosine 5'-diphosphate

鸟苷-5ˊ-二磷酸二钠盐(酵母),GDP

Guanosine 5'-diphosphate作为一种关键的核苷二磷酸，通过G蛋白信号转导作为细胞内信号级联反应的调节剂。

GC34609 Guanosine 5'-diphosphate disodium salt

鸟苷-5'-二磷酸二钠盐,GDP disodium salt

Guanosine 5'-diphosphate disodium salt作为一种关键的核苷二磷酸，通过G蛋白信号转导作为细胞内信号级联反应的调节剂。

GC47792 Nordeoxycholic Acid

去甲脱氧氯酸,23-NDCA, 23-Nordeoxycholic Acid

A metabolite of norcholic acid and derivative of deoxycholic acid

GC36902 Phthalic acid mono-2-ethylhexyl ester

邻苯二甲酸单乙基己基酯,MEHP

Phthalic acid mono-2-ethylhexyl ester (MEHP) 是邻苯二甲酸二己酯 (DEHP) 的主要生物活性代谢物，可抑制 CYP17 的 17，20 裂合酶活性。

GC12516 Spironolactone

螺内酯; SC9420

Competitive mineralocorticoid (aldosterone) receptor antagonist

GD07844 Compound 48/80

钙调蛋白抑制剂

GC27439 BMS-986449

BMS986449, BMS 986449

BMS-986449是一种IKZF2(Helios)/IKZF4(Eos)降解剂和CELMoD分子胶，能够在原代Treg细胞中重定向E3泛素连接酶Cereblon与Helios和Eos的相互作用并诱导其降解,可用于抗肿瘤免疫。

GE10005 RNase A, Bovine pancreas

RNA酶;核糖核酸酶A（牛胰）;核糖核酸酶I

RNase A, Bovine pancreas (Ribonuclease A) cleaves the 3' end of RNA to pyrimidine and actively cleaves RNA at each pyrimidine residue.

GC63270 α-Glucosidase

α-葡萄糖苷酶; α-D-Glucosidase

α-葡萄糖苷酶是一种碳水化合物水解酶，催化从底物的非还原端释放α-葡萄糖苷酶。

GC27438 2-(2-Chlorophenyl)-6,7-difluoroquinazolin-4(3H)-one

2-(2-氯苯基)-6,7-二氟喹唑啉-4(3H)-酮

GC10543 WST-8

2-(2-甲氧基-4-硝基苯)-3-(4-硝基苯)-5-(2,4-二磺基苯)-2H-四氮唑单钠盐

A water-soluble tetrazolium dye

GC27437 tert-Butyl (3R)-3-[(3-methylpyridin-2-yl)amino]piperidine-1-carboxylate

(3R)-3-[(3-甲基吡啶-2-基)氨基]哌啶-1-甲酸叔丁酯

GC26647 Fluoromount-G Anti fluorescence quenching sealing agent (water-soluble)

Fluoromount-G Mounting Medium

Fluoromount-G是一种水溶性、非荧光性化合物，用来对最后一步染色为水溶液体系的玻片样本进行封片，可以明显降低荧光显微镜下玻片样本分析中的荧光淬灭现象。

GC14394 Cy5 amine (non-sulfonated)

Cyanine5 amine

can be conjugated with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides.

GC64378 Valproic acid-d6

丙戊酸-D6,VPA-d6; 2-Propylpentanoic Acid-d6

Valproic acid-d6 (VPA-d6) 是 Valproic acid 的氘代物。Valproic acid (VPA; 2-Propylpentanoic Acid) 是一种 HDAC 抑制剂，IC50 值为 0.5-2 mM，抑制 HDAC1 的活性，(IC50，400 μM)，同时可诱导 HDAC2 的降解。Valproic acid 激活 Notch1 信号并抑制小细胞肺癌 (SCLC) 细胞的增殖。Valproic acid 可用于癫痫、双相情感障碍和偏头痛等的研究。

GC48886 Carbamazepine-d10

5H-二苯并[B,F]氮杂卓-5-甲酰胺-D10,CBZ-d10; NSC 169864-d10

An internal standard for the quantification of carbamazepine

GP20168 EGF Human Epidermal Growth Factor Human Recombinant