QPCT Human
目录号 : GP22212Glutaminyl-Peptide Cyclotransferase Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greater than 90.0% as determined by SDS-PAGE. | Source | Sf9,Baculovirus cells. |
| Phycical Appearance | Sterile Filtered colorless solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | Glutaminyl-Peptide Cyclotransferase; Glutaminyl Cyclase; QC;Glutaminyl-TRNA Cyclotransferase; GlutamylCyclase; EC 2.3.2.5; SQC; EC; GCT; Glutaminyl-peptide cyclotransferase. | ||
| Amino Acid Sequence | VSPSASAWPE EKNYHQPAIL NSSALRQIAE GTSISEMWQN DLQPLLIERYPGSPGSYAAR QHIMQRIQRL QADWVLEIDT FLSQTPYGYR SFSNIISTLN PTAKRHLVLA CHYDSKYFSHWNNRVFVGAT DSAVPCAMML ELARALDKKL LSLKTVSDSK PDLSLQLIFF DGEEAFLHWSPQDSLYGSRH LAAKMASTPH PPGARGTSQL HGMDLLVLLD LIGAPNPTFPNFFPNSARWF ERLQAIEHEL HELGLLKDHS LEGRYFQNYS YGGVIQDDHI PFLRRGVPVL HLIPSPFPEVWHTMDDNEEN LDESTIDNLN KILQVFVLEY LHLHHHHHH. | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. | ||
| Formulation | QPCT protein solution (0.5mg/ml) contains PhosphateBuffered Saline (pH 7.4) and 10% glycerol. | ||
Glutaminyl-Peptide Cyclotransferase, also known as QPCT is a member ofthe glutaminyl-peptide cyclotransferase family. QPCT is responsible for thebiosynthesis of pyroglutamyl peptides. Furthermore, QPCT is partial againstacidic and tryptophan residues adjacent to the N-terminal glutaminyl residueand a lack of importance of chain length following the second residue. QPCTcatalyzes N-terminal pyroglutamate formation, also in vitro, it catalyzespyroglutamate formation of N-terminally truncated form of APP amyloid-betapeptides [Glu-3]-beta-amyloid.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.