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Quercetin-d3 (hydrate)

目录号 : GC48020

A neuropeptide with diverse biological activities

Quercetin-d3 (hydrate) Chemical Structure

规格 价格 库存 购买数量
500 μg
¥1,181.00
现货
1 mg
¥2,125.00
现货

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Sample solution is provided at 25 µL, 10mM.

Description

Quercetin-d3(hydrate) is intended for use as an internal standard for the quantification of quercetin by GC- or LC-MS. Quercetin is an abundant flavonoid that has been isolated from a variety of plants and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties.1,2,3 Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) content, and increases total antioxidant capacity in the kidney in a mouse model of cadmium-induced autophagy.2 It reduces tumor growth, induces apoptosis, and halts the cell cycle at the G1 phase in an HL60 mouse xenograft model when administered at a dose of 120 mg/kg every four days.1 Quercetin (30 µM) also inhibits histamine release from antigen-stimulated RBL-2H3 cells and decreases the expression of TNF-α, IL-1β, IL-6, and IL-8 induced by PMACI in HMC-1 cells.3

1.Calgarotto, A.K., Maso, V., Junior, G.C.F., et al.Antitumor activities of quercetin and green tea in xenografts of human leukemia HL60 cellsSci. Rep.8(1)3459(2018) 2.Yuan, Y., Ma, S., Qi, Y., et al.Quercetin inhibited cadmium-induced autophagy in the mouse kidney via inhibition of oxidative stressJ. Toxicol. Pathol.29(4)247-252(2016) 3.Park, H.H., Lee, S., Son, H.Y., et al.Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cellsArch. Pharm. Res.31(10)1303-1311(2008)

化学性质

Cas No. N/A SDF
Canonical SMILES OC1=CC(O)=C(C(C(O)=C(C2=C([2H])C([2H])=C(O)C(O)=C2[2H])O3)=O)C3=C1.O
分子式 C15H7D3O7.XH2O 分子量 305.3
溶解度 DMSO: slightly soluble,Methanol: slightly soluble 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 3.2755 mL 16.3773 mL 32.7547 mL
5 mM 0.6551 mL 3.2755 mL 6.5509 mL
10 mM 0.3275 mL 1.6377 mL 3.2755 mL
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