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Home >> Signaling Pathways >> Neuroscience >> Pain Research

Pain Research(疼痛研究)

  1. Cat.No. 产品名称 Information
  2. GC91690 TASP0277308 TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).
  3. GC91681 Loxoprofen-SRS Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen .
  4. GC91680 4-Acetamido Antipyrine

    4-AAAP,NSC 331807

     4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .
  5. GC91488 Proxymetacaine (hydrochloride)

    Proparacaine

     Proxymetacaine is an anesthetic.
  6. GC91375 Promethazine Sulfoxide 盐酸普罗米嗪是组胺H1受体拮抗剂普罗米嗪的代谢产物。它由细胞色素P450（CYP）同工酶CYP2D6将普罗米嗪转化而成。
  7. GC91355 Chlorphenesin Carbamate

    Maolate; NSC 82943; OC-201

     氯苯甲酸甲酯是一种肌肉松弛剂。在浓度为1毫摩尔时，它可以降低电流刺激腹根引起的背根电位以及L-谷氨酸诱导的孤立青蛙脊髓运动神经元放电。
  8. GC26144 Menthol

    Menthol 是个天然的止痛剂。Menthol 通过抑制神经元细胞膜的 Ca++ 电流，刺激冷感受器，从而产生凉的感觉。
  9. GC91278 Doxepin N-oxide (hydrate)

    多西平的代谢产物。
  10. GC91237 Mitraciliatine

    一种生物碱，是μ-阿片受体的部分激动剂和κ-阿片受体的激动剂。
  11. GC91233 Mepivacaine-d3

    一种用于测量美派卡因的内部标准
  12. GC91190 Propoxur-d3

    一种用于测量丙氧乐的内部标准。
  13. GC90884 TNP-ATP (sodium salt)

    这是一种ATP衍生物，可以作为嘌呤能受体P2Y1、P2X3和P2X2/3的拮抗剂。
  14. GC90790 4-hydroxy Xylazine O-Glucuronide (lithium salt)

    p-hydroxy Xylazine O-Glucuronide, para-hydroxy Xylazine O-Glucuronide

    一种二甲基苯乙胺的代谢产物。
  15. GC90789 3-hydroxy Xylazine

    一种二甲基苯乙胺的代谢产物。
  16. GC90605 Tat-CBD3 (trifluoroacetate salt)

    一种抑制Ca2.2-CRMP2蛋白质相互作用的药物
  17. GC90532 UFP101 (trifluoroacetate salt)

    一种合成肽和痛觉受体拮抗剂。
  18. GC90517 2,2'-Bisnaloxone

    商业制备的纳洛酮中可能存在杂质。
  19. GC90489 AC 187 (trifluoroacetate salt)

    Acetyl-(Asn30,Tyr32)-Calcitonin8-32, Acetyl-Asn30,Tyr32Salmon Calcitonin (8 -37), Acetyl-Asn30,Tyr32 sCT(8 -37)

    一种钙降素和淀粉样蛋白受体的拮抗剂。
  20. GC52507 Orexin A amide (bovine, human, mouse, rat) (trifluoroacetate salt)

    Hypocretin 1, OXA

     A hypothalamic neuropeptide
  21. GC52438 CGRP (8-37) (mouse, rat) (trifluoroacetate salt)

    Calcitonin Gene-Related Peptide (8-37), CGRP8-37, VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2

     A CGRP receptor antagonist
  22. GC52424 Bradykinin Fragment (1-5) (trifluoroacetate salt)

    Arg-Pro-Pro-Gly-Phe, BK1-5, RPPGF

     A metabolite of bradykinin
  23. GC52412 TT-232 (trifluoroacetate salt) A synthetic peptide derivative of somatostatin
  24. GC52409 BAM-22P (8-22) (human, mouse, rat, bovine) (trifluoroacetate salt)

    BAM 8-22, Bovine Adrenal Medulla 8-22

     A neuropeptide and MRGPRX1 agonist
  25. GC52407 BAM-22P (human, mouse, rat, bovine) (trifluoroacetate salt)

    Bovine Adrenal Medullary Docosapeptide, YGGFMRRVGRPEWWMDYQKRYG

     A neuropeptide
  26. GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate)

    Neuropeptide Q, NPQ, NWTPQAMLYLKGAQ-NH2, SPX1

     An endogenous peptide and agonist of GAL2 and GAL3
  27. GC52342 P4pal10 (trifluoroacetate salt)

    Palmitoyl-SGRRYGHALR-amide, Palmitoyl-SGRRYGHALR-NH2

     A PAR4 and FPR2 antagonist and an FFAR2 agonist
  28. GC52243 Corynantheidine

    (-)-Corynantheidine, 9-demethoxy Mitragynine

     An alkaloid with antinociceptive activity
  29. GC52177 Perphenazine Sulfoxide

    奋乃静亚砜

     An active metabolite of perphenazine
  30. GC52154 Inflammasome Inhibitor 4b An inhibitor of NLRP3 inflammasome activation
  31. GC52145 Bradykinin (human, mouse, rat, bovine) (acetate)

    Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, BK, RPPGFSPFR-OH

     An endogenous vasodilator
  32. GC52077 CTP354 A deuterated derivative of L-838,417
  33. GC52049 Myricetin 3-galactoside

    杨梅素 3-O-半乳糖苷

     A flavonoid with diverse biological activities
  34. GC52020 Lamotrigine-d3

    拉莫三嗪-[D3]

     An internal standard for the quantification of lamotrigine
  35. GC52005 Triazolomethylindole-3-acetic Acid

    三唑甲基吲哚-3-乙酸

     A metabolite of rizatriptan
  36. GC49909 Met-Enkephalinamide (trifluoroacetate salt)

    Met5-Enkephalin amide, Methionine-Enkephalin amide, H-Tyr-Gly-Gly-Phe-Met-NH2, H-YGGFM-NH2

     A peptide opioid receptor agonist
  37. GC49882 Hemokinin 1 (human) (trifluoroacetate salt)

    HK-1, TGKASQFFGLM-NH2, Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2

     A peptide agonist of NK1 receptors
  38. GC49880 Bradykinin (trifluoroacetate salt) An endogenous vasodilator
  39. GC49865 γ-D-Glutamylglycine (trifluoroacetate salt)

    γ-DGG

     An excitatory amino acid antagonist
  40. GC49861 1-Carboxycyclohexaneacetic Acid

    加巴喷丁杂质E

     A potential impurity in commercial preparations of gabapentin
  41. GC49858 Desipramine-d4 (hydrochloride)

    盐酸去郁敏D4

     An internal standard for the quantification of desipramine
  42. GC49836 Benoxaprofen

    氧苯恶唑丙酸,LRCL 3794

     An NSAID
  43. GC49829 DL-threo-β-Hydroxyaspartic Acid

    D,L-苏-Β-羟基天门冬氨酸

     An EAAT inhibitor
  44. GC49761 Capsaicin-d3

    TRANS-辣椒素-D3,(E)-Capsaicin-d3

     An internal standard for the quantification of capsaicin
  45. GC49752 4,5-Desisopropylidene Topiramate

    4,5-Desisopropylidene TPM

     An inactive metabolite of topiramate
  46. GC49747 Flunixin-d3

    氟尼辛-D3

     An internal standard for the quantification of flunixin
  47. GC49720 Leu-Enkephalin (trifluoroacetate salt)

    Leucine enkephalin, Leu5enkephalin, Tyr-Gly-Gly-Phe-Leu-OH

     A neuropeptide and δ- and ?-opioid receptor agonist
  48. GC49705 Pentapeptide-18 (acetate)

    Ala2,Leu5-Enkephalin, D-Ala2Leucine-Enkephalin, Tyr-D-Ala-Gly-Phe-Leu-OH

     A peptide derivative of enkephalin
  49. GC49639 Akuammine

    (-)-Akuammine, Vincamajoridine

     An indole alkaloid with analgesic activity
  50. GC49608 Larixyl Acetate

    Larixol Acetate

     A diterpenoid with TRPC6 inhibitory and analgesic activities
  51. GC49559 Hydroxymethyl Tolperisone (hydrochloride) A metabolite of tolperisone

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