Autoimmunity(自身免疫)

Cat.No. 产品名称 Information

GC92001 PQA-18

Prenylated Quinolinecarboxylic Acid Compound-18

PQA-18是p21活化激酶2 (PAK2；IC50 = 10 nM)，一种免疫抑制剂，Ppc-1的衍生物。

GC91947 BH400 BH400是过氧化物酶体增殖物激活受体α (PPARα)的激动剂和干扰素基因刺激因子抑制剂(STING；Ic50 = 8.1 μm)。

GC91921 Fenclofenac

RX-67408

Fenclofenac是一种非甾体抗炎药（NSAID）和COX抑制剂（COX-1和COX-2的IC50分别为7和4μM）。

GC91911 Napirimus Napirimus是一种免疫抑制剂。

GC91909 Fenoprofen-13C6 (sodium salt hydrate) Fenoprofen-13C6 (sodium salt hydrate)旨在用作通过GC或LC-MS定量非诺洛芬的内标。

GC91820 PDIC-NS PDIC-NS is an activator of stimulator of interferon genes (STING).

GC91789 LB244 LB244 is an irreversible STING antagonist.

GC91777 NVS-STG2 NVS-STG2 is an agonist of stimulator of interferon genes (STING).

GC91690 TASP0277308 TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).

GC91688 PDIC-NN PDIC-NN is an intermediate in the synthesis of PDIC-NS , an activator of stimulator of interferon genes (STING) with anticancer activity.

GC91659 BDW-OH BDW-OH is an active metabolite of the STING agonist and prodrug BDW568 .

GC91595 PDIC-NC PDIC-NC is an activator of stimulator of interferon genes (STING) and an anticancer agent.

GC26431 Pentacosafluorotridecanoic Acid

全氟十三烷酸，PFTrDA

Perfluorotridecanoic Acid (Perfluorinated Compound (PFC)) is a perfluorinated alkyl acid (PFAA) and a possible organic pollutant.

GC26242 Alexa Fluor 594 labeled Concanavalin A

刀豆蛋白A来源于洋刀豆(刀豆)，Alexa Fluor 594标记;Alexa Fluor 594标记的刀豆凝集素A;Alexa Fluor594标记的刀豆球蛋白A;Ale lexa Flu or 594标记的伴刀豆球蛋白A;

刀豆蛋白A (Concanavalin ACon A) ，来源于Canavalia ensiformis洋豆 (刀豆)，是一种凝集素蛋白 (Mw 104kDa) 。

GC91424 S1PL-IN-31

Sphingosine-1-Phosphate Lyase Inhibitor 31; S1PL Inhibitor 31; S1P Lyase Inhibitor 31

S1PL-IN-31是一种抑制神经酰胺-1-磷酸（S1P）裂解酶的抑制剂（IC50 = 210 nM）。它也是平滑蛋白受体（Smo）的拮抗剂（IC50 = 440 nM）。

GC91379 BDW568 BDW568是干扰素基因刺激剂（STING）的激动剂，也是BDW-OH.1的前药形式。

GC91096 S-72

一种微管聚合抑制剂。

GC90982 STING Agonist D61

D61, Stimulator of Interferon Genes Agonist D61

STING激动剂

GC90785 STING Agonist 23

Stimulator of Interferon Genes Agonist 23

STING激动剂

GC90784 STING Agonist 12L

Stimulator of Interferon Genes Agonist 12L

STING激动剂

GC90774 1-Linoleoyl Lysophosphatidic Acid (sodium salt)

1-Linoleoyl-2-hydroxy-sn-glycero-3-PA, 1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate, 1-Linoleoyl LPA

一种甘油磷脂

GC90710 CAY10723 (hydrochloride)

AFM30a, AMF30a

一种PAD2抑制剂

GC90705 BSP-16

LF250

STING激动剂

GC90631 LL-37 (human) (scrambled) (trifluoroacetate salt)

Cathelicidin, CAP-18, FALL-39, hCAP-18

LL-37（人类）的阴性对照。

GC90243 Myelin Basic Protein (human, bovine, rat) (trifluoroacetate salt)

MBP

一种能引起脑炎的肽。

GC52487 Ganglioside GM4 (chicken egg) (ammonium salt)

Ganglioside G7, Monosialoganglioside GM4

A sphingolipid

GC52455 Pixantrone-d8 (maleate) An internal standard for the quantification of pixantrone

GC52419 MOG (35-55) (mouse, rat) (trifluoroacetate salt)

MEVGWYRSPFSRVVHLYRNGK, Myelin Oligodendrocyte Glycoprotein (35-55)

An MOG antigen peptide

GC52413 5-Aminosalicylic Acid-d7

5-ASA-d7, Mesalamine-d7, Mesalazine-d7

An internal standard for the quantification of 5-aminosalicylic acid

GC52394 LC10 A lipidoid derivative of lithocholic acid

GC52385 Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt)

EKPKVEAYKAAAAPA-OH, MBP (85-99) Peptide Antagonist

An MBP (85-99) antagonist

GC52371 Vimentin (G146R) (139-159)-biotin Peptide

Biotin-GQGKSRLRDLYEEEMRELRRQ, Biotin-GQGKSRLRDLYEEEMRELRRQ (X=Citrulline), VIM (G146R) (139-159)-biotin

A biotinylated mutant vimentin peptide

GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide

Biotin-GQGKS(Cit)LGDLYEEEMRELRRQ, Biotin-GQGKSXLGDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (R144)-biotin

A biotinylated and citrullinated vimentin peptide

GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide

Biotin-GQGKS(Cit)L(Cit)DLYEEEMRELRRQ, Biotin-GQGKSXLXDLYEEEMRELRRQ (X=Citrulline), Citrullinated VIM (G146R) (R144 + R146)-biotin

A biotinylated and citrullinated mutant vimentin peptide

GC52364 Vimentin (139-159)-biotin Peptide

VIM (139-159)-biotin

A biotinylated vimentin peptide

GC52363 Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide

Biotin-A-Cit-TKQTA-Cit-KSTGGKAP-Cit-KQLA, Biotin-AXTKQTAXKSTGGKAPXKQLA (X=Citrulline), Citrullinated Histone H3.1-biotin

A biotinylated and citrullinated histone H3 peptide

GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide

Citrullinated Enolase-1-biotin, α-Enolase Peptide (Citrulline Residues 8 + 14)

A biotinylated and citrullinated α-enolase peptide

GC52334 ENPP1 Inhibitor 4e

cGAMP-compound 4e

An ENPP1 inhibitor

GC52326 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) A biotinylated and pegylated form of LL-37

GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil

GC52291 KAS 08 A STING activator

GC52274 Y-33075 (hydrochloride)

RKI-983, SNJ-1656, Y-39983

An inhibitor of ROCK2

GC52253 α-Enolase (1-19)-biotin Peptide

Enolase-1 (1-19)-biotin

A biotinylated α-enolase peptide

GC52185 (R,S)-Anatabine-d4

RAC-盐酸安那他品-D4

An internal standard for the quantification of (R,S)-anatabine

GC20007 Ginsenoside CK

20(S)-人参皂苷 C-K; Compound K

Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.