Bone Growth & Remodeling(骨骼生长 & 重塑)

Cat.No. 产品名称 Information

GC91768 GSK205 (hydrobromide) GSK205 is an inhibitor of transient receptor potential vanilloid 4 (TRPV4) and transient receptor potential ankyrin 1 (TRPA1; IC50s = 4.19 and 5.56 µM, respectively, for the rat channels).

GC91690 TASP0277308 TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).

GC91449 Ipamorelin (acetate)

Aib-His-D-2-Nal-D-Phe-Lys-NH₂; NNC 26-0161

Ipamorelin是一种五肽生长激素分泌素（GHS）和GHS受体1a（GHS-R1a）激动剂。

GC91109 17β-Estradiol 3-O-Sulfate (sodium salt)

Estradiol Sulfate, E2S

17β-雌二醇的一种不活性代谢产物。

GC90949 Adenosine-5'-O-(3-thiotriphosphate) (sodium salt)

Adenosine 5'-(γ-thio)-triphosphate, ATPγS

一种P2Y11受体激动剂。

GC90945 17β-Estradiol-2,4,16,16-d4 3-sulfate (sodium salt)

E2-2,4,16,16-d4 3-sulfate, β-Estradiol-2,4,16,16-d4 3-sulfate, Estradiol-2,4,16,16-d4 3-sulfate, 17β-Oestradiol-2,4,16,16-d4 3-sulfate

一种用于量化17β-雌二醇-3-硫酸盐的内部标准。

GC52384 NFAT Inhibitor (cell-permeable) (trifluoroacetate salt)

Nuclear Factor Activated T cells Inhibitor, RRRRRRRRRRRGGGMAGPHPVIVITGPHEE, 11R-VIVIT

A cell-permeable form of NFAT inhibitor

GC52376 BMP2-derived Peptide (trifluoroacetate salt)

Bone Morphogenic Protein 2-derived Peptide, KIPKASSVPTELSAISTLYL-NH2

A synthetic peptide

GC52129 3-Amino-5-hydroxybenzoic Acid

3-氨基-5-羟基苯甲酸

A biosynthetic precursor to ansamycin antibiotics

GC49890 β-Glycerophosphate-d5 (sodium salt hydrate)

Glycerol 2-Phosphate-d5

An internal standard for the quantification of β-glycerophosphate

GC49416 Gap 27 (trifluoroacetate salt)

43Gap27, SRPTEKTIFII

A connexin-mimetic peptide

GC49305 H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)

H-RGDC-OH

An RGD-containing tetrapeptide

GC49303 Ganoderic Acid DM

灵芝酸 DM

A triterpenoid with diverse biological activities

GC49148 Plitidepsin

普拉泰,Aplidine

A depsipeptide with diverse biological activities

GC49061 Pam2CSK4 (trifluoroacetate salt)

Pam2Cys-Ser-(Lys)4

A bacterial lipopeptide and TLR2 agonist

GC48023 Raloxifene-d4 (hydrochloride)

雷洛昔芬-D4,盐酸盐

An internal standard for the quantification of raloxifene

GC47619 Menaquinone 4-d7

甲萘醌 4-d7

An internal standard for the quantification of menaquinone 4

GC47538 L-Ascorbic Acid 2-phosphate (magnesium salt hydrate)

2-Phospho-L-ascorbic acid magnesium hydrate

A long-acting ascorbic acid derivative

GC47417 GW 9662-d5 A neuropeptide with diverse biological activities

GC47287 Eltenac

依尔替酸

A non-selective COX inhibitor

GC47090 Cinacalcet-d3 (hydrochloride)

AMG 073-d3 hydrochloride

A neuropeptide with diverse biological activities

GC46768 Abaloparatide (acetate)

BA 058, BIM 44058

A synthetic derivative of PTHrP and an agonist of PTHR1

GC46471 17β-hydroxy Exemestane-d3 A neuropeptide with diverse biological activities

GC60970 KY19382

A3051

KY19382 (A3051) is a Wnt/β-catenin signalling activator through inhibitory effects on both CXXC5–DVL interaction and GSK3β activity with IC50s of 19 nM and 10 nM, respectively.

GC39623 DCC-3014

DCC-3014

Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC50s of <0.01 μM and 0.1-1 μM, respectively.