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Home >> Signaling Pathways >> Obesity, Appetite Control & Diabetes >> Diabetes

Diabetes(糖尿病)

  1. Cat.No. 产品名称 Information
  2. GC92134 Glucose-dependent Insulinotropic Polypeptide (human) (trifluoroacetate salt)

    Gastric Inhibitory Peptide; GIP

     Glucose-dependent Insulinotropic Polypeptide (human) (trifluoroacetate salt)是一种内源性42个氨基酸的肽促胰岛素素激素，在葡萄糖反应中诱导胰岛素分泌。
  3. GC92133 Glucose-dependent Insulinotropic Polypeptide (1-42) (porcine) (trifluoroacetate salt)

    Gastric Inhibitory Peptide (1-42); GIP (1-42)

     Glucose-dependent Insulinotropic Polypeptide (1-42) (porcine) (trifluoroacetate salt)是一种内源性42个氨基酸的肽肠促胰岛素激素，可诱导胰岛素分泌。
  4. GC92132 SAR441255 (sodium salt) SAR441255 (sodium salt)是胰高血糖素样肽1受体GLP-1R、葡萄糖依赖性促胰岛素多肽受体GIPR和胰高血糖激素受体GCGR的肽三重激动剂。
  5. GC92128 Dapiglutide (sodium salt) Dapiglutide (sodium salt)是一种双胰高血糖素样肽1受体GLP-1R和GLP-2R激动剂。
  6. GC92125 Liraglutide (acetate)

    NN 2211

     Liraglutide (acetate)是胰高血糖素样肽1（GLP-1）受体的强效激动剂，也是含有棕榈酸基团的GLP-1（7-37）的合成衍生物。
  7. GC92122 KBP-066 (trifluoroacetate salt) KBP-066 (trifluoroacetate salt)是一种胰淀素和降钙素双重CT受体激动剂。
  8. GC92119 GLP-1 (7-36) acid (human, mouse, rat, porcine, bovine)

    Glucagon-like Peptide 1 (7-36) acid

     GLP-1 (7-36) acid (human, mouse, rat, porcine, bovine)是激素和GLP-1受体（GLP-1R）激动剂GLP-1（7-36）酰胺的衍生物。
  9. GC92118 Taspoglutide (acetate)

    [Aib8,35]hGLP-1(7-36)NH2; BIM-51077C

     Taspoglutide (acetate)是胰高血糖素样肽1受体的激动剂（GLP-1R；人受体Ki=1.1nM）。
  10. GC92116 Semaglutide Main Chain (9-37)

    Semaglutide Intermediate 29; Semapeptide

     Semaglutide Main Chain (9-37)是合成semaglutide的肽起始原料。
  11. GC92093 GLP-1 (7-17) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    Glucagon-like Peptide 1 (7-17)

     GLP-1 (7-17) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)是内源性肠促胰岛素GLP-1的肽片段。
  12. GC92088 GLP-1 (28-36) amide (trifluoroacetate salt)

    Glucagon-like Peptide 1 (28-36) amide; Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2

     胰高血糖素样肽1GLP-1 (28-36) amide (trifluoroacetate salt)是内源性GLP-1R激动剂GLP-1（7-36）酰胺的肽和活性代谢产物。
  13. GC92079 GLP-1 (7-15) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

    Glucagon-like Peptide 1 (7-15)

     GLP-1 (7-15) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)是内源性肠促胰岛素激素GLP-1的肽片段。
  14. GC92058 GLP-1 (7-13) (human, mouse, rat, bovine) (trifluoroacetate salt)

    Glucagon-like Peptide 1 (7-13); His-Ala-Glu-Gly-Thr-Phe-Thr-OH

     GLP-1 (7-13) (human, mouse, rat, bovine) (trifluoroacetate salt)是内源性肠促胰岛素激素GLP-1的肽片段。
  15. GC92043 9(10)-Nitrooleate

    9(10)-Nitrooleic Acid; OA-NO2; 9(10)-nitro-9-trans-Octadecenoic Acid

     9(10)-Nitrooleate是一种硝基烯内源性脂质信号分子9-硝基油酸酯的混合物。
  16. GC91981 Sergliflozin A Sergliflozin A是钠葡萄糖共转运蛋白2的抑制剂（SGLT2；Ki=2.39 nM用于人类转运蛋白），也是依他硼酸司格列净的活性代谢产物。
  17. GC91977 TrkB Agonist Prodrug R13

    TrkB-IN-1; Tropomyosin-related Kinase B Agonist Prodrug R13; Tropomyosin-related Kinase B Inhibitor 1

     TrkB Agonist Prodrug R13（R13）是原肌球蛋白相关激酶B（TrkB）激活剂7,8-二羟基黄酮的前药形式。
  18. GC91934 Insulin Sensitizer C59 Insulin Sensitizer C59是胰岛素诱导的葡萄糖转运蛋白4（Glut4）质膜易位的增强剂。
  19. GC91933 E17241

    4-(1,3-Dithiolan-2-yl)-N-(3-hydroxypyridin-2-yl)benzamide

     E17241是编码ATP结合盒转运蛋白1的基因ABCA1表达的诱导剂；亚家族A（ABCA1）。
  20. GC91929 KOTX1 KOTX1是醛脱氢酶1A3 (ALDH1A3；IC50 = 5.14 nM)。
  21. GC91922 6,6-Dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine 6,6-Dimethyl-3-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1-benzothiophen-2-amine是胰高血糖素样肽1受体GLP-1R阳性变构调节剂PAM。
  22. GC91544 Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH

    Fmoc-Lys(tBuOCO-(CH2)16-CO-Glu(AEEA-AEEA)-OtBu)-OH

     Fmoc-L-Lys[Oct-(OtBu)-Glu-(OtBu)-AEEA-AEEA]-OH is a building block in the synthesis of the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide .
  23. GC91493 Semaglutide Side Chain Semaglutide side chain is a synthetic intermediate.
  24. GC72222 Survodutide Survodutide（BI 456906）是一种强效的选择性胰高血糖素受体/GLP-1受体（GCGR/GLP-1R）双重激动剂，在CHO-K1细胞中的EC50分别为0.52 nM和0.33 nM。
  25. GC72096 Bamadutide Bamadutide（SAR425899）是一种强效的双胰高血糖素样肽-1受体/胰高血糖激素受体激动剂。
  26. GC70855 LSN3318839 LSN3318839是一种口服有效的胰高血糖素样肽-1受体(GLP-1R)的阳性变构调节剂。
  27. GC91480 Exendin-4 (3-39) amide (trifluoroacetate salt)

    Exendin (3-39)

     Exendin-4 (3-39)酰胺是一种糖肽样肽1受体（GLP-1R）激动剂，也是exendin-4 (48-86)酰胺的活性代谢物。
  28. GC91123 C18 Ganglioside GM3-d3 (d18:1/18:0-d3) (ammonium salt, synthetic)

    C18 GM3-d3, N-ω-CD3-Octadecanoyl monosialoganglioside GM3, Monosialoganglioside GM3-d3, N-Stearoyl Monosialoganglioside GM3-d3

    一种用于量化神经节苷脂GM3的内部标准。
  29. GC91042 Tauro-Obeticholic Acid (sodium salt)

    Obeticholic Acid Taurine Conjugate, Tauro-OCA, Tauro-6-Ethyl-CDCA, Tauro-6-Ethylchenodeoxycholic Acid, T-ECDCA

    一种欧贝替胆酸的活性代谢物。
  30. GC90949 Adenosine-5'-O-(3-thiotriphosphate) (sodium salt)

    Adenosine 5'-(γ-thio)-triphosphate, ATPγS

    一种P2Y11受体激动剂。
  31. GC90582 Perfluorooctanesulfonic Acid

    Heptadecafluorooctanesulfonic Acid, Perfluorooctane sulfonate, Perfluorooctylsulfonic Acid, PFOS

    一种全氟烷基物质
  32. GC90363 10(11)-Cl-BBQ

    一种作为AhR激动剂的混合物。
  33. GC90312 1-Palmitoyl-d9-2,3-Dipalmitoyl-sn-glycerol

    Glycerol Tripalmitate-d9, TG(16:0-d9/16:0/16:0), Tripalmitin-d9, 1,2,3-Tripalmitoyl-sn-glycerol-d9, Tripalmitoylglycerol-d9

    一种用于量化1,2,3-三棕榈酰-rac-甘油的内部标准。
  34. GC20142 Beta-Sitosterol

    β-谷甾醇 (purity>98%); β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%))
  35. GC20130 2-NBG-1

    NBDGlucose
  36. GC52497 Lactosylceramide (porcine RBC)

    LacCer

     A sphingolipid
  37. GC52496 Sulfatide (bovine) (sodium salt)

    Galactosylceramide I3-sulfate, Ganglioside SM4, I3SO3-GalCer, SM4, Sulfated Galactocerebroside, 3-O-Sulfogalactosylceramide

     A mixture of isolated bovine sulfatides
  38. GC52493 Glucosylceramide (bovine buttermilk)

    GluCers (buttermilk), Glucocerebrosides (buttermilk)

     A sphingolipid
  39. GC52490 Glucagon (hydrochloride) A peptide hormone
  40. GC52476 Bax Inhibitor Peptide V5 (trifluoroacetate salt)

    BIP V5, VPMLK

     A Bax inhibitor
  41. GC52428 10-oxo-12(Z)-Octadecenoic Acid-d5

    10-keto-12Z-Octadecenoic Acid-d5, 10-oxo-12-cis-Octadecenoic Acid-d5

     An internal standard for the quantification of 10-oxo-12(Z)-octadecenoic acid
  42. GC52398 10-oxo-12(Z)-Octadecenoic Acid ethyl ester

    10-keto-12Z-Octadecenoic Acid ethyl ester, 10-oxo-12-cis-Octadecenoic Acid ethyl ester

     An ester form of 10-oxo-12(Z)-octadecenoic acid
  43. GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate)

    Neuropeptide Q, NPQ, NWTPQAMLYLKGAQ-NH2, SPX1

     An endogenous peptide and agonist of GAL2 and GAL3
  44. GC52331 Lactoyl Phenylalanine

    Lac-Phe, N-Lactoyl-Phenylalanine

    A secondary metabolite
  45. GC52323 L-Isoleucine-13C6

    L-(+)-Isoleucine-13C6

     An internal standard for the quantification of L-isoleucine
  46. GC52283 L-Cysteine-15N-d3

    L-Cys-15N-d3, L-(+)-Cysteine-15N-d3, (R)-Cysteine-15N-d3

     An internal standard for the quantification of L-cysteine
  47. GC52251 Imidacloprid Impurity 1 A potential impurity in commercial preparations of imidacloprid
  48. GC52125 T-1095 An SGLT1 and SGLT2 inhibitor
  49. GC20007 Ginsenoside CK

    20(S)-人参皂苷 C-K

    A metabolite of ginsenoside Rb1 with diverse biological activity
  50. GC52071 10-oxo-12(Z)-Octadecenoic Acid

    10-keto-12Z-Octadecenoic Acid, 10-oxo-12-cis-Octadecenoic Acid

     A metabolite of linoleic acid and an activator of TRPV1
  51. GC52047 Fustin

    黄颜木素,(±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone

     A flavanone with diverse biological activities

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