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Home >> Signaling Pathways

Signaling Pathways(信号通路)

  1. Cat.No. 产品名称 Information
  2. GC68533 3'-Hydroxymirificin 3'-Hydroxymirificin (compound 3) 是一种天然产物，可从Pueraria lobata 根部获得。3'-Hydroxymirificin (compound 3) 具有雌激素和抗MCF-7人乳腺癌细胞增殖的活性。
  3. GC68531 3-Chlorogentisyl alcohol 3-Chlorogentisyl alcohol 是一种有效的 E. coli β-葡萄糖醛酸酶 β-glucuronidase 抑制剂，IC50 值为 0.74 μM，Ki 值为 0.58 μM。3-Chlorogentisyl alcohol 显示出抗增殖活性。3-Chlorogentisyl alcohol 具有抗癌和抗炎潜力。
  4. GC68525 (2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid (2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid 是一种可从 Rubus ellipticus var. obcordatus 中分离得到的皂苷。(2α,3β,4α)-2,3,19-Trihydroxyurs-12-ene-23,28-dioic acid 抑制 α-Glucosidase，其 IC50 为 1.68 mM。
  5. GC68524 (2S)-N3-IsoSer (DCHA) (2S)-N3-IsoSer DCHA 是一种点击化学试剂，是一种含有叠氮的手性 α -羟基丙酸。
  6. GC68523 (2S,3R)-Brassinazole (2S,3R)-Brassinazole 是油菜素唑 (BRZ) 的异构体。Brassinazole 作用于 6-oxo-campestanol 到 teasterone 的氧化过程，抑制油菜素类固醇 (BR) 生物合成 (brassinosteroid biosynthesis)。(2S,3R)-Brassinazole 可能是油菜素唑最活跃的形式。
  7. GC68522 (2R,3S)-Brassinazole Brassinazole (0.5, 1, 5 μM) 显着导致幼苗畸形，其形态与 BR 缺陷突变体相似。Brassinazole 会导致水芹侏儒症，改变叶片形态，例如拟南芥 BR 缺陷突变体会有的典型的向下卷曲和深绿色外观。然而，施用 10 nM BR可逆转侏儒症。
  8. GC68521 2'-O-MB-cAMP sodium

    2'-O-Monobutyryl cyclic AMP sodium

     2'-O-MB-cAMP (2'-O-Monobutyryl cyclic AM) sodium 是 Cyclic AMP 的活性前体。
  9. GC68519 2-Hydroxyisobutyric acid-d6 2-Hydroxyisobutyric acid-d6 是 2-Hydroxyisobutyric acid 的氘代物。2-Hydroxyisobutyric acid 是一种内源性代谢产物。
  10. GC68517 2-Hydroxy-4-methylbenzenesulphonic acid ammonium 2-Hydroxy-4-methylbenzenesulphonic acid ammonium 是 Policresulen 的杂质。 Policresulen 是一种有效的 NS2B/NS3 蛋白酶抑制剂，IC50 为 0.48 μg/mL。Policresulen 有效抑制 DENV2 病毒在 BHK-21 细胞中的复制，IC50 为 4.99 μg/mL。Policresulen 是蛋白酶的竞争性抑制剂，并轻微影响蛋白酶的稳定性。
  11. GC68513 2-Deoxy-D-glucose-d

    2-DG-d1; 2-Deoxy-D-arabino-hexose-d1; D-Arabino-2-deoxyhexose-d1

     2-Deoxy-D-glucose-d 是 2-Deoxy-D-glucose 的氘代物。 2-Deoxy-D-glucose 是一种葡萄糖类似物，为葡萄糖代谢抑制剂，通过作用于己糖激酶 (hexokinase) 来抑制糖酵解 (glycolysis)。
  12. GC68512 2,7-Dichlorodihydrofluorescein

    DCFH2

     2,7-Dichlorodihydrofluorescein (DCFH2) 是一种非荧光探针。2,7-Dichlorodihydrofluorescein 产生高荧光 2',7'-二氯荧光素 (DCF)，可用于活性氧测量。
  13. GC68509 (25R)-12α-Hydroxyspirost-4-en-3-one (25R)-12α-Hydroxyspirost-4-en-3-one 是由 Nocardia globerula 作用于 Hecogenin 产生的一种次要代谢物。
  14. GC68504 2-(2-Methylbenzamido)acetic acid-d7

    2-甲基马尿酸 d7

     2-(2-Methylbenzamido)acetic acid-d7 是 2-(2-Methylbenzamido)acetic acid 的氘代物。2-(2-Methylbenzamido)acetic acid 为一种代谢物，可以在尿液中检测到。
  15. GC68503 20S Proteasome activator 1 20S Proteasome activator 1 是一种有效的 20S 蛋白酶激活剂，对胰蛋白酶样位点、胰凝乳蛋白酶样位点和半胱天冬酶位点的 IC50 分别为 0.3 μM、0.7 μM 和 1.8 μM。20S Proteasome activator 1 能在细胞系统中翻译，防止致病性 α-synuclein A53T 突变体积累。20S Proteasome activator 1 可用于神经退行性疾病的研究。
  16. GC68502 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine

    1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine 可以选择作为用于研究氧化磷脂酰胆碱分子种类的挥发性化合物的模型。这个方法应用于实际食品样品，即大豆卵磷脂。
  17. GC68501 1-Palmitoyl-2-oleoyl-sn-glycerol 1-Palmitoyl-2-oleoyl-sn-glycerol 是一种内源性代谢物，也是藻殖段诱导因子 (HIF)-1 中主要的二酰基甘油。
  18. GC68496 1-Hexadecanol-d5

    十六醇-d5；鲸蜡醇-d5

     1-Hexadecanol-d5 是 1-Hexadecanol 的氘代物。 1-Hexadecanol 是脂肪醇，一种亲脂性底物。
  19. GC68495 1-Hexadecanol-d4

    十六醇-d4；鲸蜡醇-d4

     1-Hexadecanol-d4 是 1-Hexadecanol 的氘代物。 1-Hexadecanol 是脂肪醇，一种亲脂性底物。
  20. GC68494 17β-HSD1-IN-1 17β-HSD1-IN-1 (Compound 1) 是一种高度选择性的 17β-HSD1 抑制剂，抑制 17β-HSD1 和 17β-HSD2 的 IC50分别为 5.6 和 3155 nM。17β-HSD1-IN-1 可用于非小细胞肺癌 (NSCLC) 的研究。
  21. GC68493 17α-Hydroxyprogesterone-d8

    17-Hydroxyprogesterone-d8; 17-OHP-d8

     17α-Hydroxyprogesterone-d8 是 17α-Hydroxyprogesterone 的氘代物。17α-Hydroxyprogesterone (17-Hydroxyprogesterone) 是一种内源性孕激素，在其他类固醇激素（包括糖皮质激素，雄激素，和雌激素）的生物合成中作为化学中间体。
  22. GC68488 15-Azido-pentadecanoic acid

    Azido Palmitic Acid

     15-Azido-pentadecanoic acid 是一种含有叠氮基团的化学试剂。Azido Palmitic Acid 可用于通过使用简单且稳健的两步标记和检测技术来鉴定和表征翻译后棕榈酸化蛋白。
  23. GC68486 1,4-Diaminobutane-d8 dihydrochloride

    1,4-二氨基丁烷二盐酸盐-d8

     1,4-Diaminobutane-d8 dihydrochloride是氘取代的1,4-Diaminobutane dihydrochloride，它更稳定，在药物开发过程中主要用作定量示踪剂。
  24. GC68484 1,2-O-Isopropylidene-5-O-p-toluoyl-a-D-xylofuranose 1,2-O-Isopropylidene-5-O-p-toluoyl-a-D-xylofuranose 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。
  25. GC20228 α-Amyrin

    α-香树脂醇

    α-香树脂醇是一种五环三萜类化合物。
  26. GC20169 5-Bromo-4-Chloro-3-Indolyl-Alpha-D-Galactopyranoside

    Rarechem AH BS 0009; X-Alpha-Gal; X-Alpha-D-Gal; X-Alpha-D-GalACTOSIDE; X-A-Gal; 5-Bromo-4-Chloro-3-Indoxyl-Alpha-D-GalACTOPYRANOSIDE; Alpha-X-Gal; 5-Bromo-4-Chloro-3-Indolyl-Alp
  27. GC20150 PAMAM dendrimer, ethylenediamine core, generation 1.0 solution

    PAMAM 树枝状聚合物，乙二胺核，1.0 代 溶液,20wt.% in methanol
  28. GC20142 Beta-Sitosterol

    β-谷甾醇 (purity>98%); β-Sitosterol (purity>98%); 22,23-Dihydrostigmasterol (purity>98%))

     Beta-Sitosterol是一种具有多种生物活性的植物甾醇，具有抗炎、抗肿瘤、退热和免疫调节等活性。
  29. GP26449 Yellow Fever Virus Recombinant Yellow Fever Virus produced in E
  30. GP26445 Dengue Envelope-2 14 kDa Recombinant Dengue Envelope 2 produced in E
  31. GP26443 SIV GAG SIV GAG Recombinant produced in E
  32. GP26442 HIV-2 gp160 HIV-2 gp160 produced in E
  33. GP26441 HIV-1 GAG HIV-1 GAG Recombinant produced in E
  34. GP26440 HIV-1 CRF HIV-1 CRF Recombinant produced in E
  35. GP26439 HIV-1 gp41 Subtype-c Recombinant HIV-1 gp41 Subtype-c produced in E
  36. GP26438 HIV-1 gp41 Subtype-b Recombinant HIV-1 gp41 Subtype-b produced in E
  37. GP26437 HIV-1 NEF Biotin Recombinant HIV-1 nef Biotin Labeled is a full length protein produced in E
  38. GP26368 Tri a 14.0101 Recombinant Non-Specific Lipid-Transfer Protein Tri a 14 produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 13kDa
  39. GP26367 Pen a 1.0101 Recombinant Tropomyosin Pen a 1
  40. GP26366 MALD3 Recombinant Non-Specific Lipid-Transfer Protein Mal d 3 produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 12kDa
  41. GP26365 Cor a 14.0101 Recombinant 2S albumin produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 14kDa
  42. GP26364 Cor a 9 The native protein Corylus Avellana Cor a 9 is purified from hazelnut by protein chemical methods
  43. GP26363 Cor a 8.0101 Recombinant Non-specific Lipid-Transfer Protein Cor a 8 produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 11kDa
  44. GP26352 THBD Human THBD Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 500 amino acids (22-515a
  45. GP26200 TYRO3 Mouse TYRO3 Mouse produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 628 amino acids (31-419 aa) and having a molecular mass of 68
  46. GP26187 ErbB4 Human ErbB4 Human Recombinant produced in HEK293 Cells is a single, glycosylated polypeptide chain containing 863 amino acids (26-649 a
  47. GP26181 ST6GALNAC5 Human ST6GALNAC5 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 316 amino acids (30-336a
  48. GP26172 PGD Human, Active PGD Human Recombinant produced in E
  49. GP26169 NQO1 Human, Active NQO1 Human Recombinant produced in E
  50. GP26168 MMP9 Mouse MMP9 Mouse produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 711 amino acids (20-730 a
  51. GP26167 MMP2 Mouse MMP2 Mouse produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 644 amino acids (30-662 aa) and having a molecular mass of 72

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