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Home >> Signaling Pathways

Signaling Pathways(信号通路)

  1. Cat.No. 产品名称 Information
  2. GC91866 Apelin-36 (trifluoroacetate salt) The apelin gene encodes a preproprotein that is processed to generate a variety of bioactive peptides, including those having 36, 17, or 13 amino acids (apelin-36, apelin-17, and apelin-13, respectively).
  3. GC91857 Kdo2-Lipid A (sodium salt)

    KLA

     Kdo2-Lipid A is the active component of LPS.
  4. GC91852 NFF-3 (trifluoroacetate salt) NFF-3 is a fluorogenic substrate of matrix metalloproteinases (MMPs).
  5. GC91851 Malantide (trifluoroacetate salt) Malantide is a synthetic peptide derived from the β-subunit of human phosphorylase kinase and is a fluorescent substrate for PKA and PKC.
  6. GC91849 Autocamtide-2-related Inhibitory Peptide (trifluoroacetate salt) Autocamtide-2-related inhibitory peptide is a calmodulin-dependent protein kinase II (CaMKII) inhibitor (IC50 = 40 nM) that was designed based on the sequence around the autophosphorylation site (Thr286/Thr287) in the autoinhibitory domain of the protein kinase.
  7. GC91841 Mca-VDQVDGW-K(Dnp)-NH2 (acetate)

    Caspase-7 Fluorogenic Substrate I,Mca-VDQVDGW-Lys(Dnp)-NH2

     Mca-VDQVDGW-K(Dnp)-NH2 is a substrate for caspase-7.
  8. GC91829 Acriflavine Mixture Acriflavine mixture is a mixture of proflavine, acriflavine, side-methylated proflavine, and side-methylated acriflavine.
  9. GC91820 PDIC-NS PDIC-NS is an activator of stimulator of interferon genes (STING).
  10. GC91815 BODIPY 480/508-Cholesteryl Oleate

    BODIPY 480/508-Cholesterol Oleate

     BODIPY 480/508-cholesteryl oleate is a cell-permeable and fluorescently tagged derivative of cholesteryl oleate .
  11. GC91812 Cy5-Yne (triethylamine salt)

    Sulfo-Cy5-alkyne

     Cy5-Yne is a clickable azido-reactive fluorescent probe.
  12. GC91805 DB2313 (hydrochloride) DB2313 is an inhibitor of the transcription factor PU.
  13. GC91800 CPPA-TPP

    CPPA-Triphenylphosphonium,4-Cyano-4-(phenylcarbonothioylthio)pentanoic Acid-TPP,4-Cyano-4-(phenylcarbonothioylthio)pentanoic-Triphenylphosphonium

     CPPA-TPP is a chain transfer agent conjugated to the mitochondria-targeting moiety triphenylphosphonium (TPP).
  14. GC91791 Cholic Acid 3-sulfate (potassium salt)

    3-Sulfocholate,3-Sulfocholic Acid

     Cholic acid 3-sulfate is a metabolite of the primary bile acid cholic acid .
  15. GC91790 AMG PERK 44 (hydrochloride) AMG PERK 44 is a protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 6 nM).
  16. GC91789 LB244 LB244 is an irreversible STING antagonist.
  17. GC91783 FA16 FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.
  18. GC91782 DPP-9 Inhibitor 42

    Dipeptidyl Peptidase 9 Inhibitor 42

     DPP-9 inhibitor 42 is an inhibitor of dipeptidyl peptidase 9 (DDP-9; IC50 = 0.0034 µM).
  19. GC91780 BODIPY-Linoleate BODIPY-Linoleate is a fluorescently tagged derivative of linoleic acid .
  20. GC91779 Ochratoxin C-13C20

    Ochratoxin A-13C20 ethyl ester,OTC-13C20,OTA-13C20 ethyl ester

     Ochratoxin C-13C20 (OTC-13C20) is intended for use as an internal standard for the quantification of ochratoxin C by GC- or LC-MS.
  21. GC91777 NVS-STG2 NVS-STG2 is an agonist of stimulator of interferon genes (STING).
  22. GC91776 PD-1/PD-L1 Inhibitor N11

    PD-1/PD-L1 Interaction Inhibitor,Programmed Cell Death 1/Programmed Cell Death-Ligand 1 Inhibitor N11

     PD-1/PD-L1 inhibitor N11 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1; IC50 = 6.3 nM).
  23. GC91775 h-e5'NT Inhibitor 5C

    Human Ecto-5'-nucleotidase Inhibitor 5C

     h-e5'NT Inhibitor 5C is an inhibitor of ecto-5'-nucleotidase, also known as CD73 (IC50s = 0.37 and 1.66 µM for the human and rat enzymes, respectively).
  24. GC91773 18-hydroxy Oleoyl Leucine-d7 18-hydroxy Oleoyl leucine-d7 is intended for use as an internal standard for the quantification of 18-hydroxy oleoyl leucine by GC- or LC-MS.
  25. GC91768 GSK205 (hydrobromide) GSK205 is an inhibitor of transient receptor potential vanilloid 4 (TRPV4) and transient receptor potential ankyrin 1 (TRPA1; IC50s = 4.19 and 5.56 µM, respectively, for the rat channels).
  26. GC91767 ENPP3 Inhibitor 5J ENPP3 inhibitor 5J is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) and ENPP3 (IC50s = 0.59 and 0.62 µM, respectively, for the human enzymes).
  27. GC91764 Ochratoxin B-13C20

    OTB-13C20

     Ochratoxin B-13C20 (OTB-13C20) is intended for use as an internal standard for the quantification of ochratoxin B by GC- or LC-MS.
  28. GC91761 ABBV-CLS-484 (hydrochloride)

    Osunprotafib

     ABBV-CLS-484 is a dual inhibitor of protein tyrosine phosphatase 1N (PTP1N) and PTP2N (IC50s = 2.5 and 1.8 nM, respectively).
  29. GC91737 77PD-Q

    N,N'-bis(1,4-dimethylpentyl)-p-Phenylenediamine-quinone,N,N'-bis(1,4-dimethylpentyl)-para-Phenylenediamine-quinone

     77PD-Q is a p-phenylenediamine quinone (PPD-Q) and an oxidized derivative of the antiozonant 77PD.
  30. GC91705 Etomidate-d5

    (+)-Etomidate-d5,d-Etomidate-d5,(R)-Etomidate-d5

     Etomidate-d5 is intended for use as an internal standard for the quantification of etomidate by GC- or LC-MS.
  31. GC91703 AL 34662 (formate) AL 34662 is an agonist of the serotonin (5-HT) receptor subtype 5-HT2.
  32. GC91691 viFSP1

    Versatile Inhibitor of Ferroptosis Suppressor Protein 1,Versatile Inhibitor of FSP1

     viFSP1 is a species-independent inhibitor of ferroptosis suppressor protein 1 (FSP1; IC50s = 34 and 83 nM for the human and mouse enzymes, respectively).
  33. GC91690 TASP0277308 TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).
  34. GC91689 TG46 TG46 is an inhibitor of JAK2 (IC50 = 12.5 µM).
  35. GC91688 PDIC-NN PDIC-NN is an intermediate in the synthesis of PDIC-NS , an activator of stimulator of interferon genes (STING) with anticancer activity.
  36. GC91681 Loxoprofen-SRS Loxoprofen-SRS is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 0.5 and 0.39 for recombinant human COX-1 and COX-2, respectively) and an active metabolite of the prodrug loxoprofen .
  37. GC91680 4-Acetamido Antipyrine

    4-AAAP,NSC 331807

     4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .
  38. GC91675 Artepillin C

    3,5-Diprenyl-4-hydroxy Cinnamic Acid,3,5-Diprenyl-p-hydroxy Cinnamic Acid,3,5-Diprenyl-para-hydroxy Cinnamic Acid,3,5-Diprenyl-4-Coumaric Acid,3,5-Diprenyl-p-Coumaric Acid,3,5-Diprenyl-para-Coumaric Acid

     Artepillin C is a prenylated cinnamic acid that has been found in B. grisebachii and has diverse biological activities.
  39. GC91673 CPPD-Q

    CPPD-quinone

     CPPD-Q is a p-phenylenediamine quinone (PPD-Q) and an oxidized derivative of the antiozonant CPPD.
  40. GC91672 IPPD-Q

    N-Isopropyl-N'-phenyl-p-phenylenediamine-quinone

     IPPD-Q is a p-phenylenediamine quinone (PPD-Q) and an oxidized derivative of the antiozonant IPPD .
  41. GC91670 MRSA Antibiotic 1 MRSA antibiotic 1 is an antibiotic.
  42. GC91669 m-isobutyl Ibuprofen

    Ibuprofen Impurity A,meta-isobutyl Ibuprofen

     m-isobutyl Ibuprofen is a potential impurity in commercial preparations of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor ibuprofen.
  43. GC91667 NSC 44625

    Bendroflumethiazide Impurity A,2,4-Disulfamyl-5-trifluoromethylaniline

     NSC 44625 is an inhibitor of carbonic anhydrase II (CAII; Ki = 63 nM for the human enzyme).
  44. GC91660 Alborixin Alborixin is an ionophore originally isolated from S. albus that has diverse biological activities.
  45. GC91659 BDW-OH BDW-OH is an active metabolite of the STING agonist and prodrug BDW568 .
  46. GC91658 8(Z),11(Z),14(Z)-Heptadecatrienal

    17:3-al,all-cis-8,11,14-Heptadecatrienal

     8(Z),11(Z),14(Z)-Heptadecatrienal is a polyunsaturated fatty aldehyde.
  47. GC91655 N-Methylnuciferine (iodide) N-Methylnuciferine is an aporphine alkaloid that has been found in A. cherimola and has diverse biological activities.
  48. GC91650 2-(Morpholin-4-yl)ethane-1-sulfonamide

    4-Morpholineethanesulfonamide

     2-(Morpholin-4-yl)ethane-1-sulfonamide is a byproduct in the synthesis of diazo compounds.
  49. GC91648 Akt-I-1

    Akt-IN-1

     Akt-I-1 is an inhibitor of Akt1 (IC50 = 4.6 µM).
  50. GC91647 Perfluoropropanesulfonic Acid

    Heptafluoropropanesulfonic Acid,PFPrS

     Perfluoropropanesulfonic acid is a perfluoroalkyl substance (PFAS).
  51. GC91641 4-Hydroxy-1-(2-phenylethyl)piperidine 4-Hydroxy-1-(2-phenylethyl)piperidine is a building block that has been used in the synthesis of ligands of the muscarinic acetylcholine receptor (mAChR) or sigma non-opioid intracellular receptor 1 (σ1 receptor).

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