Search Site
  • 0
    My Cart

    Click Here to Find How Many Items You Have Added:)

qq在线咨询
Home >> Signaling Pathways

Signaling Pathways(信号通路)

  1. Cat.No. 产品名称 Information
  2. GC25630 Methyl 3-aminopyrazine-2-carboxylate Methyl 3-aminopyrazine-2-carboxylate is used in chemical synthesis.
  3. GC25627 Menotropin

    Human Menopausal Gonadotrophin

     Menotropin (Human Menopausal Gonadotrophin) is a hormonally active medication for the treatment of fertility disturbances, which are extracted from the urine of postmenopausal women.
  4. GC25626 MELK-8a Dihydrochloride MELK-8a Dihydrochloride is a novel inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 of 2 nM.
  5. GC25624 MEISi-2 Dihydrochloride MEISi-2 Dihydrochloride is a potent MEIS inhibitor (MEISi) that significantly inhibits MEIS-luciferase reporters in vitro.The solubility of this product is not good, please choose carefully for cell experiments!
  6. GC25622 MCC-7840

    Emlenoflast

     MCC7840 (Emlenoflast), a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM.
  7. GC25618 Maropitant citrate Maropitant citrate is a novel neurokinin type-1 (NK1) receptor antagonist with anti-inflammatory and analgesic properties
  8. GC25605 Magnesium lactate trihydrate Magnesium lactate, the magnesium salt of lactic acid, is a mineral supplement that is added to some food and beverages as an acidity regulator.
  9. GC25603 M2912

    MSC2504877

     M2912 (MSC2504877) is a very potent TNKS1/TNKS2 inhibitor (IC50=0.6 nM for TNKS1) with exquisite selectivity over other PARP family enzymes and favorable compound properties. This inhibitor potently modulates the Wnt/β-catenin pathway by elevating the levels of axin2 (EC50=17 nM) and tankyrase in DLD1 cells in a dose-dependent manner resulting in reduced cellular Wnt reporter activity.
  10. GC25594 LY3405105 LY3405105 is an orally active CDK7 inhibitor with an IC50 of 92.8 nM. LY3405105 shows potential antineoplastic activity.
  11. GC25593 LY3143921 hydrate LY3143921 hydrate is an orally administered ATP-competitive CDC7 inhibitor.
  12. GC25583 Lobelin sulphate

    Lobeline sulfate, Bantron

     Lobelin sulphate (Lobeline sulfate, Bantron) is an alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. It has a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation.
  13. GC25581 LM11A-31 LM11A-31 is a small molecule p75NTR Ligand that reverses cholinergic neurite dystrophy in alzheimer's diseasemousemodels with mid- to late-stage disease progression
  14. GC25580 LLY-284 LLY-284 is the diastereomer of LLY-283, which is a potent and selective SAM-competitive chemical probe for PRMT5. LLY-284 is much less active than LLY-283 and can be used as a negative control for LLY-283.
  15. GC25579 LL-37(human) LL-37, human is a 37-residue, amphipathic, cathelicidin-derived peptide, which exhibits a broad spectrum of antimicrobial activity.
  16. GC25571 Levocetirizine

    LCZ, (R)-Cetirizine

     Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.
  17. GC25569 Lerisetron

    F 0930, F 0930RS

     Lerisetron (F 0930, F 0930RS) is a 5-HT3 receptor antagonist with IC50 of 0.81μM.
  18. GC25566 L-DAB HBR

    L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide

     L-DAB HBR (L-Dab Hydrobromide, L-2,4-Diaminobutyric acid hydrobromide) is an inhibitor of GABA (Gamma-aminobutyric acid) transaminase with IC50 of >500 μM
  19. GC25563 Lasmiditan succinate

    COL-144, LY573144

     Lasmiditan succinate (COL-144, LY573144) is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (Ki=2.21 nM) without vasoconstrictor activity.
  20. GC25560 Larazotide

    AT-1001

     Larazotide(AT-1001) is an antagonist of Zonulin, which appears safe and well-tolerated and may offer potential benefit as an adjuvant to immune-targeted therapies.
  21. GC25559 Lapatinib (GW-572016) Ditosylate

    GW-572016

     Lapatinib (GW-572016) Ditosylate is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM in cell-free assays, respectively.
  22. GC25558 Lanthanum(III) chloride heptahydrate Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels.
  23. GC25553 L(+)-Monosodium glutamate monohydrate

    MSG monohydrate, L-Glutamic acid monosodium salt monohydrate, Monosodium L-glutamate monohydrate, Monosodium L-glutamate monohydrate

     L(+)-Monosodium glutamate monohydrate (MSG monohydrate, L-Glutamic acid monosodium salt monohydrate, Monosodium L-glutamate monohydrate, Monosodium L-glutamate monohydrate) is a widespread nutritional additive and flavoring agent
  24. GC25552 KT-531 KT-531 (KT531) is a potent, selective HDAC6 inhibitor with IC50 of 8.5 nM, displays 39-fold selectivity over other HDAC isoforms.
  25. GC25536 JHU395 JHU395 is a novel orally bioavailable GA (glutamine antagonists) prodrug designed to circulate inert in plasma, but permeate and release active GA within target tissues. JHU395 delivers active GA to malignant peripheral nerve sheath tumor (MPNST), and significantly inhibits tumor growth without observed toxicity.
  26. GC25531 Isonipecotic acid

    4-Piperidinecarboxylic acid, 4-Carboxypiperidine, Hexahydroisonicotinic acid

     Isonipecotic acid (4-Piperidinecarboxylic acid, 4-Carboxypiperidine, Hexahydroisonicotinic acid) is a heterocyclic compound that mainly acts as a GABAA receptor partial agonist.
  27. GC25521 IMM-H007 IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK). IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signaling. IMM-H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1) degradation and facilitates its cell-surface localization in macrophages, thereby promotes cholesterol efflux.
  28. GC25499 HG106 HG106, a potent SLC7A11 inhibitor, leads to enhanced ROS generation, ER stress, and ultimately growth arrest specifically in KRAS-mutant lung adenocarcinoma (LUAD).
  29. GC25484 Guanabenz

    GBZ, GA, Wytensin, Wy-8678,BR-750

     Guanabenz (GBZ, GA, Wytensin, Wy-8678,BR-750) is an orally active central alpha 2-adrenoceptor (α2 adrenergic receptor) agonist with antihypertensive action.
  30. GC25483 GSK3368715 (EPZ019997) 3HCl GSK3368715 is a potent inhibitor of type I protein arginine methyltransferases (PRMT) that inhibits PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM.
  31. GC25482 GSK269962A HCl

    GSK269962B, GSK269962, GSK 269962

     GSK269962A HCl (GSK269962B, GSK269962) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
  32. GC25481 GSK-1520489A

    EX-A5430

     GSK-1520489A(EX-A5430) is an active Protein Kinase, Membrane Associated Tyrosine/Threonine 1 (PKMYT1) inhibitor.
  33. GC25461 GJ103 GJ-103 is an active analog of GJ072 which is a read-through compound (RTC). Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations.
  34. GC25450 GATA4-NKX2-5-IN-1

    3i-1000

    GATA4-NKX2-5-IN-1 (3i-1000) is a small-molecule compound inhibiting GATA4 and NKX2-5 transcriptional synergy with IC50 of 3 uM
  35. GC25434 Frovatriptan Succinate

    SB 209509 Succinate,VML 251 Succinate

     Frovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
  36. GC25429 Fosfomycin calcium

    phosphomycin calcium, phosphonomycin calcium

     Fosfomycin (phosphomycin, phosphonomycin) is bactericidal and inhibits bacterial cell wall biogenesis by inactivating the enzyme UDP-N-acetylglucosamine-3-enolpyruvyltransferase, also known as MurA. It enters the bacterial cell through the glycerophosphate transporter.
  37. GC25428 Foscenvivint (ICG-001) Foscenvivint (ICG-001) antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to CREB-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300. ICG-001 induces apoptosis.
  38. GC25425 Fluoroquinolonic Acid

    Ciprofloxacin Impurity A, Q-Acid

     Fluoroquinolonic Acid (Ciprofloxacin Impurity A, Q-Acid) is an antibiotic and antimicrobial agent.
  39. GC25424 Flugestone 17-acetate

    Flurogestone acetate

     Flugestone 17-acetate (Flurogestone acetate) is a corticosteroid hormone.
  40. GC25420 Fipexide hydrochloride Fipexide (hydrochloride) is a psychoactive drug of the piperazine class.
  41. GC25412 Fenoterol

    Phenoterol

     Fenoterol (Phenoterol) is a β2 adrenoreceptor agonist with bronchodilator activity.
  42. GC25411 Fasnall Fasnall, a thiophenopyrimidine, is a selective fatty acid synthase (FASN) inhibitor that shows potent anti-tumor activity.
  43. GC25410 Fasiglifam (TAK-875) Fasiglifam (TAK-875) is a selective GPR40 agonist with EC50 of 14 nM in human GPR40 expressing CHO cell line, 400-fold more potent than oleic acid.
  44. GC25405 Evodine Evodine, a natural product extracted from Evodiae fructus (EF), is a biomarker for quality assessment of EF in the Chinese Pharmacopoeia. Evodine is a potent P-gp inhibitor.
  45. GC25401 Euquinine Euquinine is generally used as a febrifuge, antimalarial, and tonic.
  46. GC25389 Ethyl potassium malonate

    Potassium 3-ethoxy-3-oxopropanoate, Malonic Acid Monoethyl Ester Potassium Salt

     Ethyl potassium malonate (Potassium 3-ethoxy-3-oxopropanoate) is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.
  47. GC25388 Ethyl chrysanthemumate

    Chrysanthemic acid ethyl ester

     Ethyl chrysanthemate (Chrysanthemic acid ethyl ester) is an allelochemical compound used as an attractant.
  48. GC25387 Ethyl (triphenylphosphoranylidene) acetate

    (Carbethoxymethylene)triphenylphosphorane, Triphenylcarbethoxymethylenephosphorane, Ethyl 2-(triphenylphosphoranylidene)acetate

     Ethyl (triphenylphosphoranylidene) acetate (Triphenylcarbethoxymethylenephosphorane, (Carbethoxymethylene)triphenylphosphorane) may act as an inhibitor of cholinesterase that inhibits AChE and BChE.
  49. GC25386 Ethacrynate Sodium

    ethacrynic acid sodium

     Ethacrynate Sodium (ethacrynic acid sodium) is the sodium salt form of ethacrynic acid, which inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules.
  50. GC25385 Esmolol Esmolol is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic or membrane stabilising activity at therapeutic dosages.
  51. GC25374 Elubiol

    dichlorophenyl imidazoldioxolan

     Elubiol (dichlorophenyl imidazoldioxolan) is used as a cosmetic ingredient for the conditioning of oily skin, effective in oil control.

Items 3651 to 3700 of 10000 total

per page
  2. 72
  3. 73
  4. 74
  5. 75
  6. 76

Set Descending Direction