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Home >> Signaling Pathways >> Apoptosis >> Other Apoptosis

Other Apoptosis(其他细胞凋亡)

  1. Cat.No. 产品名称 Information
  2. GC16145 NVP-BGT226

    NVP-BGT226 maleate

     A dual PI3K and mTOR inhibitor
  3. GC14075 Nocodazole

    诺考达唑

     Nocodazole是一种抗有丝分裂药物，是一种快速可逆的微管聚合抑制剂，在无细胞试验中抑制Abl，Abl（E255K）和Abl（T315I），IC50值分别为0.21μM，0.53μM和0.64μM。
  4. GC16976 Mitotane (Lsodren)

    米托坦; 2,4′-DDD; o,p'-DDD

     An inhibitor of steroidogenesis
  5. GC11762 Meloxicam (Mobic)

    美洛昔康

     A selective COX-2 inhibitor
  6. GC17057 Lithocholic Acid

    石胆酸; 3α-Hydroxy-5β-cholanic acid

     A toxic secondary bile acid
  7. GC10474 Laquinimod (ABR-215062)

    拉喹莫德; ABR-215062

     An immunomodulator
  8. GC17866 INCB28060

    卡马替尼; INC280; INCB28060

     An inhibitor of HGFR (c-Met)
  9. GC16880 Flurbiprofen

    氟比洛芬; dl-Flurbiprofen

     A non-selective COX inhibitor
  10. GC13029 AZD2014

    3-[2,4-双((3S)-3-甲基吗啉-4-基)吡啶并[5,6-E]嘧啶-7-基]-N-甲基苯甲酰胺,AZD 2014; AZD-2014

     A potent dual mTORC1/2 inhibitor
  11. GC15055 AZ 628

    AZ-628; AZ628

     A Raf kinase inhibitor
  12. GC11786 Acetylcysteine

    乙酰半胱氨酸; N-Acetylcysteine; N-Acetyl-L-cysteine; NAC

     乙酰半胱氨酸是半胱氨酸的 N-乙酰基衍生物。
  13. GC15281 K-252c

    孢菌素甙元,Staurosporinone

     A cell-permeable PKC inhibitor
  14. GC14256 Tivantinib (ARQ 197)

    (3R,4R)-3-(5,6-二氢-4H-吡咯并[3,2,1-IJ]喹啉-1-基)-4-(1H-吲哚-3-基)吡咯烷-2,5-二酮,ARQ-197;ARQ197

     An inhibitor of c-Met
  15. GC10970 WP1130

    WP 1130; WP-1130

     A deubiquitinase inhibitor
  16. GC10225 Dacomitinib (PF299804, PF299)

    达克替尼; PF-00299804; PF-299804

     A pan-ErbB receptor tyrosine kinase inhibitor
  17. GC15904 PP242

    PP242; PP-242

     Potent inhibitor of mTOR kinase in both mTORC1 and mTORC2
  18. GC15134 Fludarabine Phosphate (Fludara)

    磷酸氟达拉滨; NSC 118218 phosphate

     A prodrug form of fludarabine and 2-fluoro-ara-ATP
  19. GC12573 Temsirolimus

    西罗莫司脂化物,Torisel;CCI-779;CCI 779;CCI779

     A specific inhibitor of mTOR activity
  20. GC15818 RAF265

    CHIR-265;RAF 265;RAF-265;CHIR265

     A B-Raf and VEGFR2 inhibitor
  21. GC15680 Perifosine

    哌立福新; KRX-0401; NSC 639966; D21266

    Perifosine 是 Akt 的抑制剂 。
  22. GC10647 FR 180204

    ERK Inhibitor II

     A potent, cell-permeable inhibitor of ERK1/2
  23. GC17785 Macitentan

    马西替坦; ACT-064992

     A dual ETA/ETB receptor antagonist
  24. GC10944 Butein

    紫铆因; 2’,3,4,4’-tetrahydroxy Chalcone

     A plant polyphenol
  25. GC16991 PQ 401 An inhibitor of IGF-1R
  26. GC10069 NSC 23766 trihydrochloride Inhibitor of Rac1
  27. GC17886 Stattic

    STAT3 Inhibitor V

     Stattic是第一个非肽类小分子STAT3抑制剂，能有效抑制STAT3的激活和核转位。
  28. GC11015 PD168393 An irreversible EGFR kinase inhibitor
  29. GC10467 Irbesartan

    厄贝沙坦; SR-47436; BMS-186295

    An AT1 receptor antagonist
  30. GC12094 PHT-427

    4-十二烷基-N-1,3,4-噻二唑-2-基苯磺酰胺

     An inhibitor of Akt and PDPK1
  31. GC15658 R406(free base) A potent and selective Syk inhibitor
  32. GC16380 AZD8055

    CCG-168

     AZD8055是一种新型的ATP竞争性mTOR抑制剂，IC50 为0.8 nmol/L，Ki为1.3 nmol/L。
  33. GC15870 AT7519

    4-[(2,6-二氯苄基)氨基]-N-4-哌啶1H-吡唑-3-羧胺,AT7519M

     A Cdk inhibitor
  34. GC16835 LY2228820

    5-[2-(叔丁基)-4-(4-氟苯基)-1H-咪唑-5-基]-3-(2,2-二甲基丙基)-3H-咪唑并[4,5-B]吡啶-2-胺甲磺酸盐,LY2228820 dimesylate

     A potent inhibitor of p38α MAP kinase
  35. GC15047 PHA-793887

    3-甲基-N-[1,4,5,6-四氢-6,6-二甲基-5-[(1-甲基-4-哌啶基)甲酰基]吡咯并[3,4-C]吡唑-3-基]丁酰胺

     A CDK inhibitor
  36. GC11892 AEE788 (NVP-AEE788)

    6-[4-[(4-乙基-1-哌嗪)甲基]苯基]-N-[(1R)-1-苯基乙基]-7H-吡咯并[2,3-D]嘧啶-4-胺,NVP-AEE 788

     An inhibitor of EGFR and VEGFR tyrosine kinases
  37. GC13394 Ispinesib (SB-715992)

    伊斯平斯; SB-715992

     An Eg5 inhibitor
  38. GC14144 Fludarabine

    氟达拉滨; F-ara-A; NSC 118218

     Fludarabine是一种抑制DNA合成的嘌呤类似物。
  39. GC16868 Sulfasalazine

    柳氮磺吡啶; NSC 667219

     A prodrug form of 5-aminosalicylic acid
  40. GC16732 TSU-68 (SU6668,Orantinib)

    SU6668; TSU-68

     An inhibitor of select receptor tyrosine kinases
  41. GC15166 Perindopril Erbumine

    培哚普利叔丁胺; Perindopril tert-butylamine salt; S-9490 erbumine

     An orally active ACE inhibitor
  42. GC17955 Vatalanib (PTK787) 2HCl

    瓦他拉尼,PTK787 dihydrochloride; CGP-797870 dihydrochloride; ZK-222584 dihydrochloride

     A potent and selective VEGF receptor inhibitor
  43. GC11202 Epothilone A

    埃博霉素A,Epo A

     An antimicrotubule agent
  44. GC17094 Acitretin

    阿维A; Ro 10-1670

     A retinoid
  45. GC13598 MGCD-265

    N-(3-氟-4-(2-(1-甲基-1H-咪唑-4-基)噻吩并[3,2-B]吡啶-7-氧基)苯基氨基硫代甲酰基)-2-苯乙酰胺

     A c-Met and VEGFR2 inhibitor
  46. GC16818 BX-912 A potent inhibitor of PDK1
  47. GC14957 OSI-930

    噻尔非尼

     A dual inhibitor of Kit and VEGFR2
  48. GC17240 Epothilone B (EPO906, Patupilone)

    埃博霉素B; EPO 906; Patupilone

     Microtubule stabilizing agent
  49. GC10662 WYE-354

    4-[6-[4-[(甲氧羰基)氨基]苯基]-4-(4-吗啉基)-1H-吡唑并[3,4-D]嘧啶-1-基]-1-哌啶羧酸甲酯

     Potent inhibitor of mTOR in both mTORC1 and mTORC2
  50. GC13091 CP-724714

    2-甲氧基-N-[(2E)-3-[4-[[3-甲基-4-[(6-甲基-3-吡啶基)氧基]苯基]氨基]-6-喹唑啉基]-2-丙烯-1-基]乙酰胺

     A selective HER2/ErbB2 tyrosine kinase inhibitor
  51. GC15779 Cabozantinib (XL184, BMS-907351)

    卡博替尼; XL184; BMS-907351

     Cabozantinib (XL184,BMS-907351) 是一种新型 MET 和 VEGFR2 抑制剂，可同时抑制转移、血管生成和肿瘤生长。

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