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Home >> Signaling Pathways >> Apoptosis >> Other Apoptosis

Other Apoptosis(其他细胞凋亡)

Cat.No. 产品名称 Information
GC14366 Thioguanine
6-硫鸟嘌呤,Thioguanine; 2-Amino-6-purinethiol
A thiopurine analog
GC15589 WHI-P154
2-溴-4-(6,7-二甲氧基喹唑啉-4-基氨基)苯酚
A JAK3 inhibitor
GC10035 TG101209
N-(1,1-二甲基乙基)-3-[[5-甲基-2-[[4-(4-甲基-1-哌嗪基)苯基]氨基]-4-嘧啶基]氨基]苯磺酰胺,TG-101209
An inhibitor of JAK2, FLT3, RET, and JAK3
GC13433 AZ 960
5-氟-2-[[(1S)-1-(4-氟苯基)乙基]氨基]-6-[(5-甲基-1H-吡唑-3-基)氨基]-3-吡啶腈,AZ-960,AZ960
A JAK2 inhibitor
GC17050 CYT387
莫洛替尼,Cyt-387,MOMELOTINIB,CYT 387,CYT 11387
A potent inhibitor of JAK1 and JAK2
GC15980 WP1066
(2E)-3-(6-溴-2-吡啶基)-2-氰基-N-[(1S)-1-苯基乙基]-2-丙烯酰胺

An inhibitor of STAT3
GC14324 TG101348 (SAR302503)
N-(1,1-二甲基乙基)-3-[[5-甲基-2-[[4-[2-(1-吡咯烷基)乙氧基]苯基]氨基]-4-嘧啶基]氨基]苯磺酰胺,Tg-101348,SAR-302503
A JAK2 inhibitor
GC17586 Tofacitinib (CP-690550) Citrate
枸橼酸托法替尼; Tasocitinib citrate; CP-690550 citrate
A pan-JAK inhibitor
GC15295 AUY922 (NVP-AUY922)
VER-52296, AUY-922, AUY 922, Luminespib
AUY922 (NVP-AUY922)是一种高效且选择性的 HSP90抑制剂，对 HSP90α和 HSP90β的 IC₅₀ 值分别为 13nM和 21nM。
GC11720 17-AAG (KOS953)
坦螺旋霉素; 17-AAG; NSC 330507; CP 127374
17-AAG（格尔德霉素）是一种天然的苯醌安沙霉素抗生素，是第一个确定的 Hsp90 抑制剂。
GC18008 PCI-34051
N-羟基-1-(4-甲氧基苄基)-1H-吲哚-6-甲酰胺,PCI34051, PCI 34051
A potent, selective HDAC8 inhibitor
GC13055 Mocetinostat (MGCD0103, MG0103)
N-(2-氨基苯基)-4-([[4-(吡啶-3-基)嘧啶-2-基]氨基]甲基)苯甲酰胺,MGCD-0103
An orally available HDAC inhibitor
GC14998 Rocilinostat (ACY-1215)
Ricolinostat
A selective inhibitor of HDAC6
GC12191 LY-411575
(AS)-N-[(1S)-2-[[(7S)-6,7-二氢-5-甲基-6-氧代-5H-二苯并[B,D]氮杂卓-7-基]氨基]-1-甲基-2-氧代乙基]-3,5-二氟-ALPHA-羟基苯乙酰胺
A γ-secretase inhibitor
GC14209 Apoptosis Activator 2
1-(3,4-二氯苄基)-1H-吲哚-2,3-二酮
An activator of caspases
GC10801 Disulfiram
双硫仑; Tetraethylthiuram disulfide; TETD
An irreversible inhibitor of aldehyde dehydrogenase
GC10510 LDN 57444
Ubiquitin C-terminal Hydrolase L1 Inhibitor, UCHL1 Inhibitor
An inhibitor of UCH-L1
GC13508 Trametinib (GSK1120212)
曲美替尼; GSK1120212; JTP-74057
Trametinib (GSK1120212, JTP-74057) 是第二代 MEK 激酶小分子抑制剂。
GC15568 Dasatinib (BMS-354825)
达沙替尼; BMS-354825
An inhibitor of Abl and Src
GC11931 BKM120
BKM-120,Buparlisib,BKM 120,NVP-BKM120,NVP-BKM-120
An inhibitor of class I PI3K isoforms
GC10397 PD0325901
N-[(2R)-2,3-二羟基丙氧基]-3,4-二氟-2-[(2-氟-4-碘苯)氨基]苯甲酰胺,PD0325901,PD-0325901,PD 0325901,PD325901,PD 325901,PD-325901
PD0325901是一种具口服活性、选择性和非ATP竞争性的丝裂原活化蛋白激酶激酶（MEK）抑制剂，IC₅₀值为0.33nM。
GC17369 Sorafenib
索拉非尼; Bay 43-9006
索拉非尼Sorafenib是Raf-1和B-Raf的多激酶抑制剂，IC50分别为6 nM和22 nM;Sorafenib对VEGFR-2 VEGFR-3 PDGFR-β Flt-3和c-KIT也有抑制作用，IC50值分别为90 nM、20 nM、57 nM、59 nM和68 nM;索拉非尼能诱导自噬细胞凋亡和激活铁死亡，并具有抗肿瘤活性。
GC10512 Y-27632 dihydrochloride
y-27632, Y27632, Y-27632 dihydrochloride, Y 27632
Y-27632 dihydrochloride 作为一种选择性 Rho 激酶抑制剂，是一种新型支气管扩张剂。
GC12942 DAPT (GSI-IX)
gamma-Secretase Inhibitor IX, DAPT, GSI-IX
DAPT (GSI-IX) 是一种具有口服活性的 γ-分泌酶抑制剂，对人原代神经元培养物中产生的总淀粉样蛋白-β (Aβ) 和 Aβ42 的 IC50 分别为 115 nM 和 200 nM。
GN10122 Linalool
芳樟醇
A monoterpene alcohol with diverse biological activities
GN10751 Dictamnine
白鲜碱; Dictamnine; Dectamine
An alkaloid with diverse biological activities
GN10506 Umbelliferone
7-羟基香豆素; 7-Hydroxycoumarin; Hydrangin; NSC 19790
A derivative and metabolite of coumarin with diverse biological activities
GN10456 L-Theanine
L-茶氨酸; L-Glutamic Acid γ-ethyl amide; Nγ-Ethyl-L-glutamine
A neuroprotective amino acid
GN10113 Cepharanthine
千金藤碱
A biscoclaurine alkaloid
GN10358 Berbamine hydrochloride
盐酸小檗胺
A bisbenzylisoquinoline alkaloid with diverse biological activities
GN10213 Sinomenine Hydrochloride
盐酸青藤碱; Cucoline hydrochloride
A natural anti-inflammatory alkaloid
GN10666 Isoalantolactone
异土木香内酯; (+)-Isoalantolactone; Isohelenin
A sesquiterpene lactone with diverse biological activities
GN10503 Piceatannol
白皮杉醇; Astringenin; trans-Piceatannol
Piceatannol(3,3 '，4,5 ' -反式三羟基二苯乙烯)是天然存在的白藜芦醇羟基化类似物。
GN10797 Tangeretin
桔皮素; Tangeritin; NSC53909; NSC618905
Tangeretin是一种从柑橘皮中提取的天然多甲氧基黄酮化合物，是Notch-1的抑制剂。
GN10269 Wedelolactone
蟛蜞菊内酯
A natural NF-κB inhibitor
GN10504 Echinocystic acid
刺囊酸
A triterpene with diverse biological activities
GN10318 Danshensu
丹参素
A salvianolic acid with diverse biological activities
GN10361 Pseudolaric Acid B
土荆皮乙酸
Compound from Chinese traditional medicine with reported antifungal, anticancer actions
GN10543 caudatin
告达亭苷元
A C-21 steroid with anticancer activity
GN10035 9-Methoxycamptothecin
10-甲氧基喜树碱
9-Methoxycamptothecin (MCPT) 分离自 Nothapodytes foetida，通过抑制拓扑异构酶具有抗肿瘤活性。 9-Methoxycamptothecin (MCPT) 在癌症中诱导强烈的 G2/M 期阻滞和细胞凋亡。
GN10507 Baohuoside I
宝藿苷 I; Icariin-II; Icariside-II
宝活苷 I 是一种从淫羊藿中分离出来的黄酮类化合物，可作为 CXCR4 抑制剂，下调 CXCR4 表达，诱导细胞凋亡并具有抗肿瘤活性。
GN10123 Columbianadin
二氢欧山芹醇当归酸酯
A coumarin with diverse biological activities
GN10005 Schisandrin C
五味子丙素; Schizandrin-C; Wuweizisu-C
A lignan with diverse biological activities
GN10484 Amentoflavone
穗花杉双黄酮; Didemethyl-ginkgetin
A biflavonoid with diverse biological activities
GN10733 Carnosic acid
鼠尾草酸
An antioxidant
GN10302 Hypericin
金丝桃素
An anthroquinone derivative
GN10103 Neferine
甲基莲心碱; (-)-Neferine
An alkaloid with diverse biological activities
GN10783 (R) Ginsenoside Rh2
20(R)-人参皂苷Rh2
A steroid glycoside with diverse biological activities
GN10802 Brazilin
巴西苏木素
A flavonoid with diverse bioactivites
GN10275 Protosappanin B
原苏木素B(原巴西苏木素),(-)-Protosappanin B
Protosappanin B 是一种从 Lignum Sappan 中提取的酚类化合物。抗癌活性。 Protosappanin B 在人膀胱癌细胞中诱导细胞凋亡并导致 G1 细胞周期停滞。