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Home >> Signaling Pathways >> Apoptosis >> Other Apoptosis

Other Apoptosis(其他细胞凋亡)

  1. Cat.No. 产品名称 Information
  2. GC19037 ARS-853 An inhibitor of KRASG12C
  3. GC18404 Lometrexol

    洛美曲索,DDATHF

     A GART inhibitor
  4. GC18206 WT161 A potent inhibitor of HDAC6
  5. GC18173 TM5441 A PAI-1 inhibitor
  6. GC15168 Urolithin A

    尿石素A

    A metabolite of ellagic acid with diverse biological activities
  7. GC14791 F16 A potential antitumor agent
  8. GC10628 nor-NOHA (acetate)

    Nω-hydroxy-nor-Arginine

     nor-NOHA（醋酸盐）（α-氨基酸 N(omega) -Hydroxy-Nor-L-arginine）是一种有效且可逆的选择性精氨酸酶抑制剂，nor-NOHA（醋酸盐）的效力大约是 40 倍NOHA 抑制未受刺激的小鼠巨噬细胞催化 l-精氨酸水解为 l-鸟氨酸（nor-NOHA IC(50) 值 12 77777#177;5µM。
  9. GC11716 SIRT1/2 Inhibitor IV

    Cambinol,NSC 112546,SIRT1 Inhibitor II,SIRT2 Inhibitor VI

     Cell-permeable inhibitor of SIRT1 and SIRT2
  10. GC11217 CUR 61414

    G-856

     A potent inhibitor of hedgehog-induced activity
  11. GC14411 Apoptozole

    Apoptosis Activator VII

     An inhibitor of Hsp70
  12. GC17119 8-Prenylnaringenin

    8-异戊烯基柚皮素

     A phytoestrogen
  13. GC11988 15-acetoxy Scirpenol

    15-乙酰蛇形菌素

     A trichothecene mycotoxin
  14. GC10661 Destruxin B

    黑僵菌素 B

     An insecticidal mycotoxin
  15. GC15225 COTI-2 An activator of mutant forms of p53
  16. GC11989 Nortriptyline (hydrochloride)

    盐酸去甲替林; Desmethylamitriptyline hydrochloride; Desitriptilina hydrochloride

     A tricyclic antidepressant
  17. GC17649 Mebendazole

    甲苯咪唑

     A broad-spectrum anthelmintic that inhibits microtubules
  18. GC16409 Oligomycin B

    寡霉素 B

     A nonselective inhibitor of the mitochondrial F1FO ATP synthase
  19. GC15880 Penicillic Acid

    青霉酸,NSC 402844

     A mycotoxin that inhibits quorum sensing
  20. GC16350 Actinonin

    放线酰胺素,(-)-Actinonin,Ro 06-1467

     An aminopeptidase inhibitor
  21. GC16823 Enniatin Complex

    恩镰孢菌素复合物

     A complex mixture of ionophores
  22. GC10601 Ubiquitin Isopeptidase Inhibitor I

    NSC 144303

     An activator of caspases
  23. GC17287 Iberin

    3-甲基亚磺酰丙基异硫氰酸酯,NSC 321801

    A natural isothiocyanate
  24. GC12124 Selonsertib (GS-4997)

    GS-4997

     An ASK1 inhibitor
  25. GC17023 HLCL-61 A PRMT5 inhibitor
  26. GC13630 MK-4101

    5-(3,3-二氟环丁基)-3-[4-[4-甲基-5-[2-(三氟甲基)苯基]-4H-1,2,4-三唑-3-基]双环[2.2.2]辛烷-1-基]-1,2,4-恶二唑

     A Smoothened receptor antagonist
  27. GC16151 NSC348884

    N1,N1,N2,N2-四[(6-甲基-1H-苯并咪唑-2-基)甲基]-1,2-乙二胺

     A nucleophosmin inhibitor
  28. GC15282 LOXO-101 (Larotrectinib) sulfate

    (3S)-N-[5-[(2R)-2-(2,5-二氟苯基)-1-吡咯烷基]吡唑并[1,5-A]嘧啶-3-基]-3-羟基-1-吡咯烷甲酰胺硫酸盐,LOXO-101 sulfate; ARRY-470 sulfate

     A pan-Trk inhibitor
  29. GC15142 PD-1/PD-L1 inhibitor 1 (BMS-1)

    BMS-1

     PD-1/PD-L1 inhibitor 1 是一种 PD-1/PD-L1 相互作用抑制剂，IC50 值介于 6 和 100 nM . PD-1/PD-L1 调节细胞信号通路和表观遗传修饰，从而抑制 T 细胞和 B 细胞的增殖和效应子功能。
  30. GC13648 CC-223

    CC-223; ATG-008

     A potent, selective inhibitor of mTOR
  31. GC16039 LJH685

    2,6-二氟-4-[4-[4-(4-甲基-1-哌嗪基)苯基]-3-吡啶基]苯酚

     An inhibitor of RSKs
  32. GC11837 MI-136 A menin-MLL inhibitor
  33. GC12962 Isatin

    靛红,Indoline-2,3-dione

     Isatin (Indoline-2,3-dione) 是一种有效的单胺氧化酶 (MAO) 抑制剂，IC50 为 3 μM。
  34. GC16517 Eugenol

    丁香酚

     丁香酚是一种存在于丁香中的精油，具有抗菌、驱虫和抗氧化活性。
  35. GC10855 Etretinate

    依曲替酯; Ro 10-9359

     A second-generation retinoid
  36. GC11935 Escin

    七叶皂苷

     七叶皂苷是一种从七叶树 (Aesculus hippocastanum) 种子中分离出来的三萜皂苷的天然化合物，可用作血管保护性抗炎、抗水肿和抗伤害剂。
  37. GC14503 IC261

    SU5607

     A reversible inhibitor of CK1
  38. GC17603 PS-1145

    IKK Inhibitor X

     An IKKβ inhibitor
  39. GC14929 Monastrol

    (±)-Monastrol

     Reversible inhibitor of the motor protein Eg5
  40. GC10265 Manumycin A

    手霉素A

     A farnesyltransferase inhibitor with antitumor activity
  41. GC17555 NVP-TNKS656

    TNKS656

     A TNKS2 inhibitor
  42. GC14815 GMX1778 (CHS828)

    N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍,GMX1778

     A pyridyl cyanoguanidine anti-tumor agent
  43. GC12003 VR23 A proteasome inhibitor
  44. GC16214 DEL-22379

    N-[2,3-二氢-3-[(5-甲氧基-1H-吲哚-3-基)亚甲基]-2-氧代-1H-吲哚-5-基]-1-哌啶丙酰胺

     An inhibitor of ERK dimerization
  45. GC16762 PD-1/PD-L1 inhibitor 2

    PD1-PDL1抑制剂2,BMS202

     A PD-1/PD-L1 interaction inhibitor
  46. GC15399 Dp44mT

    2-(二-2-吡啶基亚甲基)-N,N-二甲基肼基硫代甲酰胺

     An iron chelator with antiproliferative effects
  47. GC17425 Sodium Tauroursodeoxycholate (TUDC)

    牛磺熊去氧胆酸钠; Tauroursodeoxycholic acid sodium; TUDCA sodium; UR 906 sodium

     Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium 是一种内质网 (ER) 应激抑制剂。 Tauroursodeoxycholate 显着降低凋亡分子的表达，例如 caspase-3 和 caspase-12。 Tauroursodeoxycholate 也抑制 ERK。
  48. GC17828 BI-847325 A selective dual MEK/Aurora kinase inhibitor
  49. GC14488 NPS-1034

    2-(4-氟苯基)-N-[3-氟-4-[(3-苯基-1H-吡咯并[2,3-B]吡啶-4-基)氧基]苯基]-2,3-二氢-1,5-二甲基-3-氧代-1H-吡唑-4-甲酰胺

     A dual MET/AXL inhibitor
  50. GC16875 FLLL32

    (2E,2'E)-1,1'-环己基亚基二[3-(3,4-二甲氧基苯基)-2-丙烯-1-酮]

     An inhibitor of JAK2/STAT3 signaling
  51. GC15161 Calcium D-Panthotenate

    泛酸钙; Calcium pantothenate; Calcium D-pantothenate; Vitamin B5 calcium salt

     D-泛酸钙（维生素B5钙盐）是一种维生素，可以降低苹果汁中棒曲霉素的含量。

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