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Home >> Signaling Pathways >> Cardiovascular

Cardiovascular(心血管)

Cardiovascular

The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment. read more

Products for  Cardiovascular

  1. Cat.No. 产品名称 Information
  2. GC49683 N-desethyl-N-methyl Vardenafil

    N-去乙基-N-甲基伐地那非

     A potential impurity found in commercial preparations of vardenafil
  3. GC49682 Dabigatran-d3

    BIBR 953-d3; BIBR 953ZW-d3

     An internal standard for the quantification of dabigatran
  4. GC49679 Sauvagine (trifluoroacetate salt) A neuropeptide hormone
  5. GC49677 Olmesartan-d6

    奥美沙坦 d6

     An internal standard for the quantification of olmesartan
  6. GC49671 2,3-Oxidosqualene

    2,3环氧角鲨烯

     An intermediate in the biosynthesis of sterols
  7. GC49653 Ramipril Diketopiperazine

    雷米普利二酮哌嗪

     A potential impurity found in commercial preparations of ramipril
  8. GC49638 Ambrisentan-d3

    安倍生坦-D3氘代

     An internal standard for the quantification of ambrisentan
  9. GC49634 Isoflupredone

    异氟泼尼松

     A glucocorticoid and mineralocorticoid receptor agonist
  10. GC49629 6β-hydroxy Prednisolone

    泼尼松龙杂质D

     A metabolite of prednisolone
  11. GC49614 Acenocoumarol-d4

    (±)-Acenocoumarin-d4, (±)-Nicoumalone-d4

     Acenocoumarol-d4 是氘标记的 Acenocoumarol。
  12. GC49576 Abnormal Cannabidiol-d3

    Abn-CBD-d3, o-CBD, ortho-Cannabidiol

     Internal standard for the quantification of abnormal cannabidiol
  13. GC49564 Carazolol-d7

    咔唑-D7,(±)-Carazolol-d7; DL-Carazolol-d7; Suacron-d7

     An internal standard for the quantification of carazolol
  14. GC49556 Cl-Necrostatin-1

    7-Cl-Nec-1, 7-Cl-Necrostatin-1, Nec-1f

     A RIPK1 inhibitor
  15. GC49543 Hepcidin-25 (trifluoroacetate salt)

    H-DTHFPICIFCCGCCHRSKCGMCCKT-OH

     A peptide hormone
  16. GC49518 Fluindione

    氟茚二酮

     A vitamin K antagonist
  17. GC49511 Nicorandil N-oxide

    尼可地尔氮氧化物

     A metabolite of nicorandil
  18. GC49509 Glycyl-L-Glutamine (hydrate)

    甘氨酰-L-谷氨酰胺

     A dipeptide fragment of β-endorphin
  19. GC49500 Stobadine

    2,8-二甲基-2,3,4,4A,5,9B-六氢-1H-吡啶并[4,3-B]吲哚二盐酸盐

     A pyridoindole antioxidant
  20. GC49497 Dopamine-d4 (hydrochloride)

    盐酸多巴胺D4,ASL279-d4

     An internal standard for the quantification of dopamine
  21. GC49496 Homocitrulline-d3

    ε-Carbamyllysine-d3, L-ε-Amino-Carbamoyl-Lysine-d3

     An internal standard for the quantification of homocitrulline
  22. GC49493 IRL 1620 (trifluoroacetate salt)

    PMZ-1620, SPI 1620, Suc-Glu9, Ala11,15-ET-1(8-21)

     A peptide ETB receptor agonist
  23. GC49486 Meglutol-d3

    氘代3-羟基-3-甲基(D3)

     An internal standard for the quantification of meglutol
  24. GC49484 [D-Trp8]-γ-MSH (trifluoroacetate salt) An MC3R agonist
  25. GC49467 β-Aescin

    beta-七叶素

     A triterpenoid saponin with diverse biological activities
  26. GC49459 Desmopressin (trifluoroacetate salt)

    Adiuretin, DDAVP

     A vasopressin receptor agonist
  27. GC63781 (R)-BAY-899 (R)-BAY-899 是 BAY-899 的 R 型异构体。BAY-899 是一种口服有效和选择性的促黄体生成激素受体 (LH-R) 拮抗剂，对 hLH (人 LH) 和 rLH (大鼠 LH) 的 IC50 分别为 185 nM 和 46 nM。
  28. GC63768 Oxythiamine diphosphate ammonium Oxythiamin diphosphate ammonium 是一种有效的转酮酶 (TK) 抑制剂。
  29. GC63748 SPOP-IN-6b dihydrochloride SPOP-IN-6b dihydrochloride 是一种有效的斑型 POZ 蛋白 (SPOP) 抑制剂，IC50 为 3.58 μM。
  30. GC63712 XL388-C2-amide-PEG9-NH2 hydrochloride XL388-C2-amide-PEG9-NH2 hydrochloride 是一种可用于合成 C26 连接的雷帕霉素类似物的中间体。
  31. GC63698 Leucomalachite green-d5

    隐色孔雀石绿-D5

     Leucomalachite green-d5 是 Leucomalachite green 的氘代物。Leucomalachite green 是一种三苯甲烷燃料，可用于检测血液。Leucomalachite green 是孔雀石绿的主要代谢物，是一种潜在的致癌物、致畸物和诱变剂。
  32. GC63697 BSc3094 BSc3094 是一种 Tau aggregation 抑制剂。BSc3094 可用于阿尔茨海默病 (AD) 的研究。
  33. GC63685 (6R,7S)-Cefminox sodium heptahydrate

    头孢米诺钠

     (6R,7S)-Cefminox sodium heptahydrate 是 Cefminox sodium heptahydrate 的异构体。Cefminox sodium heptahydrate 是一种 β-内酰胺头孢菌素抗生素，具有广谱抗菌活性。
  34. GC63677 VPC-80051 racemate VPC-80051 is an potent inhibitor of hnRNP A1 splicing activity that targets hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line.
  35. GC63673 ABT-384 ABT-384 是一种强效选择性的 11-β-羟基类固醇脱氢酶1型 (11β-HSD1) 抑制剂。ABT-384 对啮齿类、猴和人 11β-HSD1 具有很高的亲和力，Ki 值在 0.1-2.7 nM。ABT-384 阻断活性皮质醇的再生。ABT-384 可用于阿尔兹海默症的研究。
  36. GC63665 Benzylacyclouridine

    BAU; 5-Benzylacyclouridine

     Benzylacyclouridine (BAU) 是一种有效且特异性的尿苷磷酸化酶抑制剂，尿苷磷酸化酶是尿苷分解代谢中的第一种酶。Benzylacyclouridine 可以调节 5-氟尿嘧啶 (5-FU) 及其衍生物的细胞毒副作用。
  37. GC63657 N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide

    Calcium ionophore II

     A calcium ionophore
  38. GC63638 Acetone-d6

    氘代丙酮

     Acetone-d6 是 Acetone 的氘代物，可用作核磁共振波谱 (NMR) 的溶剂。
  39. GC63637 Esfenvalerate

    S-氰戊菊酯

     Esfenvalerate 是拟除虫菊酯杀虫剂 fenvalerate 的四个异构体之一。
  40. GC63633 N7-Methyl-guanosine-5’-triphosphate-5’-adenosine

    N7-甲基鸟苷-5'-三磷酸-5'-腺苷,m7GpppA

     N7-Methyl-guanosine-5’-triphosphate-5’-adenosine (m7GpppA) 是一种二核苷酸帽类似物，可用于体外 RNA 转录。
  41. GC63629 cis-2-Butene-1,4-diol

    顺式-1,2-二羟甲基乙烯

     cis-2-Butene-1,4-diol 是一种用于合成抗病毒药物 oxetanocin A 的化合物。cis-2-Butene-1,4-diol 是研究异构化与氢化和氢解反应的探针。
  42. GC63626 ZINC05007751 ZINC05007751 is a potent NIMA-related kinase NEK6 inhibitor with an IC50 of 3.4 μM, shows antiproliferative activity against a panel of human cancer cell lines and displays a synergistic effect with Cisplatin and Paclitaxel in a BRCA2 mutated ovarian cancer cell line. DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.
  43. GC63625 N-Palmitoyl-L-glutamine N-Palmitoyl-L-glutamine 是一种谷氨酰胺衍生物。
  44. GC63618 Antrafenine

    安曲非宁; Stakane

     Antrafenine (Stakane) 是一种非麻醉性缓解疼痛试剂，在药理学和毒理学研究中表现出长时间的作用和良好的耐受性。
  45. GC63614 Trichloroacetonitrile

    三氯乙腈

     Trichloroacetonitrile 是饮用水中氯与背景有机物反应产生的一系列污染物之一。Trichloroacetonitrile 是芳基硼酸异丙醇羟基化为酚类化合物的有效活化剂。
  46. GC63600 Piperonyl alcohol

    胡椒醇

     Piperonyl alcohol 是一种苯并二恶英衍生物。它具有生物相容性，可作为引发剂用于化学合成。
  47. GC63589 NSC668394 NSC668394 是一种有效的 ezrin (Thr567) 磷酸化抑制剂，Kd 值为 12.59 μM。NSC668394 主要通过与 ezrin 结合来抑制 PKCΙ 导致的 ezrin T567 磷酸化。NSC668394 可用于预防肿瘤转移。
  48. GC63588 Palmitoyl glutamic acid

    棕榈酰谷氨酸,N-Palmitoyl-L-glutamic acid

     Palmitoyl glutamic acid (N-Palmitoyl-L-glutamic acid) 是一种酰基氨基酸，具有神经保护作用。Palmitoyl glutamic acid 用作化妆品原料。
  49. GC63587 Dichlormid

    二氯丙烯胺；烯丙酰草胺

     Dichlormid 是除草剂安全剂。Dichlormid 上调 ZmGST27 和 ZmMRP1 的表达并增加 ZmGT1。
  50. GC63586 FR054 FR054 is a novel inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3 with a remarkable anti-breast cancer effect.
  51. GC63573 Cannabigerol monomethyl ether

    O-methyl Cannabigerol, Cannabigerol monomethyl ether

     An Analytical Reference Standard

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