Cardiovascular(心血管)

Cardiovascular

The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment. read more

Products for Cardiovascular

Cat.No. 产品名称 Information
GC63409 SG3199-Val-Ala-PAB SG3199-Val-Ala-PAB 是 Tesirine 合成的中间体。Tesirine 是一种用于抗体偶联药物 (ADC) 的药物-linker 连接物，能用于多种癌症的研究。
GC63401 BPH-652 BPH-652 是 CrtM 的抑制剂，Ki 值为 1.5 nM，IC50 值为100-300 nM (S. aureus 色素形成)。
GC63368 Patisiran sodium Patisiran sodium 是一种双链小干扰 RNA，靶向 Transthyretin (TTR) 信使 RNA 内的序列。Patisiran sodium 特异性抑制突变体和野生型 TTR 的肝脏合成。Patisiran sodium 可用于研究遗传性 TTR 淀粉样蛋白症的研究。
GC63361 CR-1-30-B CR-1-30-B 是 CR-1-31-B 的一种非活性对映体。作为对照，CR-1-30-B 对 eIF4A 不起作用，并且对 MUC1-C 翻译的诱导没有明显影响。
GC63347 Peptide 78 Peptide 78，一种趋化细胞因子，由 78 个氨基酸组成，是 IL-8 或 C-X-C 趋化因子超基因家族的蛋白成员。Peptide 78 诱导中性粒细胞 (PMN) 在类风湿性关节炎 (RA) 关节方面发挥重要作用。
GC63344 PFM39 PFM39 是一种 Mirin 类似物，是一种有效的选择性 MRE11 核酸外切酶抑制剂。PFM39 阻断 dsDNA 磷酸骨架的旋转，但不抑制 TmMre11 或人类 MRE11/MRN 核酸内切酶活性。
GC63339 OSBPL7-IN-1 OSBPL7-IN-1 是一种具有口服活性的氧甾醇结合蛋白样 7 (OSBPL7) 抑制剂。OSBPL7-IN-1 促进质膜上 ABCA1 的增加而不影响 mRNA 表达。
GC63324 Rimsulfuron
砜嘧磺隆,DPX-E9636
Rimsulfuron (DPX-E9636) 是一种磺酰脲类除草剂，在玉米出苗后用于控制禾草和一些阔叶杂草。
GC63323 Pirepemat
IRL752
Pirepemat (IRL752) 是一种儿茶酚胺和认知促进剂。 Pireemat (IRL752) 可用于帕金森病的研究。
GC63301 AWL-II-38.3 AWL-II-38.3 is a potent Ephrin type-A receptor 3 (EphA3) kinase inhibitor.
GC63298 Ganoderic acid N
灵芝酸 N
A triterpene with ACE inhibitory activity
GC49443 7α-hydroxy Cholesterol
胆甾-5-烯-3,7二醇
An oxysterol and bile acid precursor
GC49436 L-3-n-Butylphthalide
(–)-3-Butylphthalide, levo-3-n-Butylphthalide, (S)-(–)-3-Butylphthalide, L-NBP
A phthalide with antiplatelet and neuroprotective activities
GC49433 Capsiate
辣椒素酯
A capsaicin analog with diverse biological activities
GC49428 O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine A major metabolite of amlodipine
GC49424 Pyridostigmine-d3 (bromide)
溴化吡啶斯的明 d3 (溴盐)
An internal standard for the quantification of pyridostigmine
GC49421 Atorvastatin lactone-d5 An internal standard for the quantification of atorvastatin lactone
GC49416 Gap 27 (trifluoroacetate salt)
43Gap27, SRPTEKTIFII
A connexin-mimetic peptide
GC49414 p-Cresol Glucuronide
4-Cresol Glucuronide, p-Tolyl-β-D-glucuronide
A metabolite of p-cresol
GC49413 Rizatriptan N-oxide
利扎曲普坦N氧化物
A potential impurity found in commercial preparations of rizatriptan
GC49410 CVT-2738
N-(2,6-二甲基苯基)-1-哌嗪乙酰胺
An active metabolite of ranolazine
GC49409 Desmethyl Ranolazine
雷诺嗪杂质
A metabolite of ranolazine
GC49408 Ramipril Diketopiperazine Acid
雷米普利杂质K
A potential impurity found in commercial preparations of ramipril
GC49406 ACT-373898 A metabolite of macitentan
GC49403 Benzarone
苯扎隆,Fragivix
An active metabolite of benzbromarone
GC49399 N-Desbutyl Dronedarone (hydrochloride)
N-[2-丁基-3-[4-[3-(丁基氨基)丙氧基]苯甲酰基]-5-苯并呋喃基]甲磺酰胺盐酸盐,SR35021 hydrochloride
An active metabolite of dronedarone
GC49389 Tritylolmesartan Medoxomil
三苯甲基奥美沙坦酯
An intermediate in the synthesis of olmesartan medoxomil
GC49387 Berberine-d6 (chloride)
Natural Yellow 18-d6 chloride
An internal standard for the quantification of berberine
GC49386 Tepoxalin
替泊沙林
A dual inhibitor of COX and 5-LO
GC49377 L-Glutamine-d5
L-谷氨酰胺-2,3,3,4,4-D5,L-Glutamic acid 5-amide-d5
An internal standard for the quantification of L-glutamine
GC49376 DL-Aspartic Acid-d3
DL-天门冬氨酸 d3
An internal standard for the quantification of aspartic acid
GC49374 L-Arginine-d7 (hydrochloride)
L-精氨酸D7盐酸盐,(S)-(+)-Arginine-d7 hydrochloride
An internal standard for the quantification of L-arginine
GC49358 Sildenafil Chlorosulfonyl
3-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑O-(4-3-D)-嘧啶-5
An intermediate in the synthesis of sildenafil
GC49349 O-Desethyl Sildenafil
西地那非杂质C
A metabolite of sildenafil
GC49346 1-(3-Chlorophenyl)biguanide (hydrochloride)
m-Chlorophenylbiguanide hydrochloride, meta-Chlorophenylbiguanide, m-CPBG, meta-CPBG
A 5-HT₃ receptor agonist
GC49343 Isoproterenol-d7 (hydrochloride)
Isoprenaline-d7
An internal standard for the quantification of isoproterenol
GC49341 Spermidine-d6 An internal standard for the quantification of spermidine
GC49340 Pitavastatin lactone-d4 An internal standard for the quantification of pitavastatin lactone
GC49338 Deltorphin II (trifluoroacetate salt)
DADELT II, D-Ala2Deltorphin II, D-Ala2, Glu4Deltorphin II, Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2
A peptide agonist of δ₂-opioid receptors
GC49333 SH-42 An inhibitor of DHCR24
GC49328 UDP-α-D-Galactose (sodium salt)
UDP-Α-D半乳糖二钠盐
A nucleotide sugar
GC49325 Dihydroxyacetone Phosphate (magnesium salt hydrate)
DHAP, Glycerone Phosphate
甘油脂前体
GC49314 Arecaidine propargyl ester (hydrobromide)
1,2,5,6-四氢-1-甲基-3-吡啶羧酸2-丙炔-1-基酯氢溴酸盐
A muscarinic M₂ agonist
GC49305 H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)
H-RGDC-OH
An RGD-containing tetrapeptide
GC49303 Ganoderic Acid DM
灵芝酸 DM
A triterpenoid with diverse biological activities
GC49301 Nesiritide (acetate) A natriuretic peptide
GC49291 rac-N-desmethyl Ivabradine-d6 (hydrochloride) An internal standard for the quantification of N-desmethyl ivabradine
GC49266 Compstatin (trifluoroacetate salt)
ICVVQDWGHHRCT
A peptide inhibitor of complement activation
GC49264 Neuromedin U-23 (rat) (trifluoroacetate salt)
NMU-23
肽 NMUR 激动剂
GC49262 Alytesin (trifluoroacetate salt) A neuropeptide with diverse biological activities