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Home >> Signaling Pathways >> Cancer Biology

Cancer Biology(癌症生物学)

Cat.No. 产品名称 Information
GC18254 DM1-SMe
N2'-去乙酰基-N2'-[3-(甲基二硫基)-1-氧代丙基]美登素
A mertansine analog
GC13315 ML-098
CID-7345532
A selective Rab7 activator
GC16765 ML-099
CID-888706
A pan activator of Ras-related GTPases
GC12876 ML-097
CID-2160985
A pan activator of Ras-related GTPases
GC12948 CID-1067700
2-[[(苯甲酰基氨基)硫代甲酰]氨基]-4,7-二氢-5,5-二甲基-5H-噻吩并[2,3-C]吡喃-3-羧酸,ML-282
A competitive GTPase inhibitor
GC13460 2-Hydroxyestradiol
雌甾-1,3,5(10)-三烯2,3,17-三醇,2-HE2,NSC 61711

A natural metabolite of estradiol
GC14778 tetramethyl Nordihydroguaiaretic Acid
EM-1421,M4N,Tetrameprocol,tetramethyl NDGA,TMNDGA
A tumor growth inhibitor
GC15555 Farnesyl Thiosalicylic Acid Amide
FTS Amide,Salirasib Amide
A potent Ras inhibitor with anti-cancer activity
GC17093 VLX600 An anticancer compound
GC16236 Fucoidan
岩藻多糖；褐藻糖胶
A sulfated polysaccharide with diverse biological activities
GC13840 Stachydrine (hydrochloride)
盐酸水苏碱
A pyrrolidine betaine with anticancer and cardioprotective effects
GC16331 Misonidazole
米索硝唑,NSC 261037,Ro 7-0582,SR 1354
A nitroimidazole that targets hypoxic cells
GC16722 CE3F4 An uncompetitive inhibitor of Epac1
GC11189 AI-10-49 AI-10-49 是一种蛋白质-蛋白质相互作用抑制剂，选择性结合 CBFβ-SMMHC 并破坏其与 RUNX1 的结合，FRET IC50 为 0.26 uM。
GC10906 RBC8 A Ral inhibitor
GC10612 BQU57 An inhibitor of RalA and RalB
GC14676 Pacritinib (SB1518)
帕克替尼
An equipotent inhibitor of FLT3 and JAK2
GC12604 Fumonisin B1
伏马菌素B1

A mycotoxin
GC15594 PX 12
2-(仲丁基二硫基)-1H-咪唑,IV-2
An irreversible inhibitor of thioredoxin-1
GP10020 Histone-H2A-(107-122)-Ac-OH
Ac-Gly-Val-Leu-Pro-Asn-Ile-Gln-Ala-Val-Leu-Leu-Pro-Lys-Lys-Thr-Glu-OH

Histone-H2A peptide
GP10005 Epidermal growth factor receptor (994-1002) acetyl/amide
Ac-Asp-Ser-Asn-Phe-Tyr-Arg-Ala-Leu-Met-amide

EGF-family receptor
GP10104 S6 Kinase Substrate Peptide 32
H2N-Lys-Glu-Ala-Lys-Glu-Lys-Arg-Gln-Glu-Gln-Ile-Ala-Lys-Arg-Arg-Arg-Leu-Ser-Ser-Leu-Arg-Ala-Ser-Thr-Ser-Lys-Ser-Gly-Gly-Ser-Gln-Lys-OH
Measures the activity of kinases that phosphorylate ribosomal protein S6.
GP10117 Endostatin (84-114)-NH2 (JKC367)
H2N-Pro-Gly-Ala-Arg-Ile-Phe-Ser-Phe-Asp-Gly-Lys-Asp-Val-Leu-Arg-His-Pro-Thr-Trp-Pro-Gln-Lys-Ser-Val-Trp-His-Gly-Ser-Asp-Pro-Asn-NH2
血管生成抑制剂
GP10098 Cdk2/Cyclin Inhibitory Peptide I
H2N-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Pro-Val-Lys-Arg-Arg-Leu-Phe-Gly-OH

Cell division protein kinase 2
GP10072 Pro-Adrenomedullin (153-185), human
H2N-Ser-Leu-Pro-Glu-Ala-Gly-Pro-Gly-Arg-Thr-Leu-Val-Ser-Ser-Lys-Pro-Gln-Ala-His-Gly-Ala-Pro-Ala-Pro-Pro-Ser-Gly-Ser-Ala-Pro-His-Phe-Leu-OH

Vasodilator
GP10142 ubiquitin specific protease 3 fragment
H2N-Ser-Thr-Thr-Ala-Ile-Cys-Ala-Thr-Gly-Leu-OH

Deubiquitinates uH2A/uH2B
GP10028 tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]
H2N-Tyr-Leu-His-Val-Glu-Pro-Glu-Lys-Glu-Val-OH

P53 binding protein fragment
GP10034 survivin (baculoviral IAP repeat-containing protein 5) (21-28)
H2N-Thr-Phe-Lys-Asn-Trp-Pro-Phe-Leu-OH

Cancer Biology Peptides
GP10145 signal transducer and activator of transcription 6 fragment
H2N-Ser-Tyr-Trp-Ser-Asp-Arg-Leu-Ile-Ile-OH

STAT6 transcription factor
GP10032 Rac GTPase fragment
H2N-Val-Phe-Asp-Glu-Ala-Ile-Arg-Ala-Val-OH

Fragment of small signaling G proteins
GP10002 prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]
H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH

Transcriptional repressor
GP10036 p53 tumor suppressor fragment
H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH

Regulates cell cycle
GP10140 MAP kinase fragment [Multiple species]
H2N-Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu-OH

Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu
GP10146 ferritin heavy chain fragment [Multiple species]
H2N-Tyr-Leu-Asn-Glu-Gln-Val-Lys-Ala-Ile-OH

Ferritin heavy chain fragment
GP10132 erbB-2
H2N-Lys-Ile-Phe-Gly-Ser-Leu-Ala-Phe-Leu-OH

Tyrosine kinase (TK) receptor
GP10141 Cytochrome P450 CYP1B1 (190-198) [Homo sapiens]
H2N-Phe-Leu-Asp-Pro-Arg-Pro-Leu-Thr-Val-OH

Sequence: H2N-FLDPRPLTV-OH
GP10007 Cytochrome c fragment (93-108)
H2N-Ala-Asn-Glu-Arg-Ala-Asp-Leu-Ile-Ala-Tyr-Leu-Lys-Gln-Ala-Thr-Lys-OH

Initiates apoptosis
GP10143 Cytochrome c - pigeon (88-104)
H2N-Lys-Ala-Glu-Arg-Ala-Asp-Leu-Ile-Ala-Tyr-Leu-Lys-Gln-Ala-Thr-Ala-Lys-OH
细胞色素 c - 鸽子 (88-104) (PCC 88-104) 对来自 B10 的鸽子细胞色素 c 引发的 T 细胞具有完全的刺激活性。
GP10017 [Ser25] Protein Kinase C (19-31)
H2N-Arg-Phe-Ala-Arg-Lys-Gly-Ser-Leu-Arg-Gln-Lys-Asn-Val-OH

PKC substrate
GP10109 Adrenorphin
H2N-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-amide

Adrenorphin 是一种阿片样物质八肽，作为 μ-阿片样物质受体的有效激动剂，Ki 为 12 nM。
GP10123 Fas C- Terminal Tripeptide
Ac-Ser-Leu-Val-OH

AC-SER-LEU-VAL-OH
GP10127 Cadherin Peptide, avian
H2N-Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-amide

Role in cell adhesion
GP10103 Laminin (925-933)
H2N-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-OH
层粘连蛋白（925-933）（CDPGYIGSR）是层粘连蛋白 B1 链上的序列。
GP10115 GTP-Binding Protein Fragment, G alpha
H2N-Cys-Gly-Ala-Gly-Glu-Ser-Gly-Lys-Ser-Thr-Ile-Val-Lys-Gln-Met-Lys-OH

Hydrolyzes GTP to GDP
GP10095 Epidermal Growth Factor Receptor Peptide (985-996)
H2N-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH

EGFR Peptide (985-996)
GP10114 Myelopeptide-2 (MP-2)
H2N-Leu-Val-Val-Tyr-Pro-Trp-OH

用于恢复人T淋巴细胞的肽
GP10113 Adrenomedullin (1-12), human
H2N-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-OH

An N-terminal fragment of adrenomedullin
GP10111 β-Pompilidotoxin
Arg-Ile-Lys-Ile-Gly-Leu-Phe-Asp-Gln-Leu-Ser-Arg-Leu

β-Pompilidotoxin (β-PMTX)，一种黄蜂毒液，可以减缓钠通道失活并增加细胞中的稳态钠电流。
GP10022 Dynamin inhibitory peptide
Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro

动力蛋白抑制肽竞争性地阻断动力蛋白与两性蛋白的结合，从而防止内吞作用。
GP10119 Gap 27
Ser-Arg-Pro-Thr-Glu-Lys-Thr-Ile-Phe-Ile-Ile

A connexin-mimetic peptide