Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC64508 γ-Aminobutyric acid-d6
4-氨基丁酸-2,2,3,3,4,4-D6,4-Aminobutyric acid-d6
γ-Aminobutyric acid-d6 (4-Aminobutyric acid-d6) 是 γ-Aminobutyric acid 的氘代物。γ-Aminobutyric acid (4-Aminobutyric acid) 是成年哺乳动物大脑中主要的抑制性神经递质，能够与离子移变 GABA 受体 (GABAA) 受体和促代谢受体 (GABAB) 受体结合发挥作用。
GC64495 Flurbiprofen axetil
氟比洛芬酯
Flurbiprofen Axetil is one of the commonly used nonsteroidal anti-inflammatory drugs (NSAIDs) that nonselectively inhibits cyclooxygenase.
GC64492 Galanthamine N-Oxide
加兰他明 N-氧化物
Galanthamine N-Oxide 是一种生物碱，分离于 Zephyranthes concolor 的球茎中。Galanthamine N-Oxide 抑制电鳗乙酰胆碱酯酶 (AChE)，EC50 为 26.2 μM。Galanthamine N-Oxide 是TcAChE，hAChE 和 hBChE 酶活性位点中底物调节的显著抑制剂。
GC64423 Repinotan hydrochloride
BAY x 3702
Repinotan hydrochloride (BAY x 3702) 是一种有效的、选择性的、可透过血脑屏障，并具有口服活性的 5-HT1A 受体激动剂，Ki 值为 0.19 nM (小牛海马)， 0.25 nM (大鼠和人类皮层) 和 0.59 nM (大鼠海马)。Repinotan hydrochloride 对其他相关受体的亲和力较弱。Repinotan hydrochloride 具有强效的神经保护作用。
GC64394 Flupyrimin Flupyrimin 是昆虫烟碱乙酰胆碱受体 (nAChR) 的拮抗剂。
GC64390 AChE-IN-3 AChE-IN-3 对 AChE 有中度抑制活性，对 NO 有较强抑制活性，其 EC50 为 0.57 μM。
GC52120 DMPE-MPEG(2000)
1,2-Dimyristoyl-rac-glycero-3-PE-methoxy-Polyethyleneglycol-2000, 1,2-DMPE-MPEG(2000)
A PEGylated form of DMPE
GC52106 5-hydroxy Isatin
5-羟基靛红
An inhibitor of MAO-A
GC52100 (Arg)9 (trifluoroacetate salt)
Nona-Arginine, Poly-Arginine-9, RRRRRRRRR
A cationic cell-penetrating peptide
GC52078 Galantamine (hydrobromide)
氢溴酸加兰他敏

An alkaloid with AChE inhibitory and nAChR potentiating activities
GC52077 CTP354 A deuterated derivative of L-838,417
GC52060 Trimipramine N-oxide
10,11-二氢-N,N,BETA-三甲基-5H-二苯并[B,F]氮杂卓-5-丙胺N-氧化物
An active metabolite of trimipramine
GC52050 Monoacetylcadaverine (hydrochloride) A metabolite of cadaverine
GC52049 Myricetin 3-galactoside
杨梅素 3-O-半乳糖苷
A flavonoid with diverse biological activities
GC52048 3-hydroxy-4-Methoxyphenethylamine (hydrochloride)
4-甲氧基多巴胺盐酸盐
A metabolite of dopamine
GC52047 Fustin
黄颜木素,(±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone
A flavanone with diverse biological activities
GC52033 S-Methyl-D-penicillamine A metabolite of D-penicillamine
GC52030 LSN2814617
LSN2814617消旋体
A positive allosteric modulator of mGluR5 receptors
GC52027 Isolariciresinol
异落叶松脂素,(+)-Cyclolariciresinol
A lignan with diverse biological activities
GC52024 Aripiprazole N-oxide
阿立哌唑-N1-氧化物
A metabolite of aripiprazole
GC52022 NT1-O14B An ionizable cationic lipidoid
GC52020 Lamotrigine-d3
拉莫三嗪-[D3]
An internal standard for the quantification of lamotrigine
GC52013 (±)-10-hydroxy-12(Z)-Octadecenoic Acid
10-hydroxy-cis-12-Octadecenoic Acid
An oxylipin and metabolite of linoleic acid
GC52007 N-hydroxylamine Dapsone
羟胺氨苯砜
An active metabolite of dapsone
GC52006 CB-096 An inhibitor of RAN translation
GC52005 Triazolomethylindole-3-acetic Acid
三唑甲基吲哚-3-乙酸
A metabolite of rizatriptan
GC52004 Amisulpride N-oxide
氨磺必利杂质11
A degradation product of amisulpride
GC19959 Methylprednisolone acetate
泼尼松龙EP杂质
A synthetic glucocorticoid and an ester form of methylprednisolone
GC19941 DL-Leucic Acid
GC49913 Davunetide (acetate)
AL-108, NAP, NAPVSIPQ
A neuroprotective ADNP-derived peptide
GC49909 Met-Enkephalinamide (trifluoroacetate salt)
Met5-Enkephalin amide, Methionine-Enkephalin amide, H-Tyr-Gly-Gly-Phe-Met-NH2, H-YGGFM-NH2
A peptide opioid receptor agonist
GC49905 Tianeptine-d6 (hydrochloride) An internal standard for the quantification of tianeptine
GC49904 rac-Eletriptan-d3 (hydrobromide) An internal standard for the quantification of eletriptan
GC49897 ELOVL1-22 An inhibitor of ELOVL1
GC49882 Hemokinin 1 (human) (trifluoroacetate salt)
HK-1, TGKASQFFGLM-NH2, Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2
A peptide agonist of NK₁ receptors
GC49881 Setmelanotide (trifluoroacetate salt)
BIM-22493, N-acetyl-RCAHFRWC-NH2, RM-493
A peptide agonist of MC4R
GC49880 Bradykinin (trifluoroacetate salt) An endogenous vasodilator
GC49875 (±)-N-desmethyl Venlafaxine (hydrochloride)
盐酸文拉法辛杂质D
A minor active metabolite of venlafaxine
GC49873 Protectin D1 methyl ester
Neuroprotectin D1 methyl ester, NPD1 methyl ester, PD1 methyl ester
An esterified form of protectin D1
GC49869 3-Methoxytyrosine
2-氨基-3-(4-羟基-3-甲氧基苯基)丙酸
An active metabolite of L-DOPA
GC49865 γ-D-Glutamylglycine (trifluoroacetate salt)
γ-DGG
An excitatory amino acid antagonist
GC49861 1-Carboxycyclohexaneacetic Acid
加巴喷丁杂质E
A potential impurity in commercial preparations of gabapentin
GC49858 Desipramine-d4 (hydrochloride)
盐酸去郁敏D4
An internal standard for the quantification of desipramine
GC49856 Choline-d9 (chloride)
氯化胆碱 d9 (氯化物)
An internal standard for the quantification of choline
GC49855 Harmalol (hydrochloride hydrate)
骆驼蓬酚盐酸盐(二水)
A β-carboline alkaloid and an active metabolite of harmaline
GC49851 Norquetiapine
11-(1-哌嗪基)二苯并[B,F][1,4]硫氮杂卓
An active metabolite of quetiapine
GC49845 Piribedil N-oxide
吡贝地尔氮氧化物
A metabolite of piribedil
GC49840 2-Methylbutyrylglycine
N-(2-甲基-1-氧代丁基)-甘氨酸
A metabolite of isoleucine
GC49838 α-Cortolone
Β-皮甾酮四醇
A metabolite of cortisol
GC49836 Benoxaprofen
氧苯恶唑丙酸,LRCL 3794
An NSAID