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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC49112 Sinapyl Alcohol

    芥子醇

     A monolignol with anti-inflammatory and antinociceptive activities
  3. GC49111 Carbamazepine 10,11-epoxide

    卡马西平10,11-环氧化物

     An active metabolite of carbamazepine
  4. GC49108 Racecadotril-d5

    消旋卡多曲杂质,Acetorphan-d5

     An internal standard for the quantification of racecadotril
  5. GC49102 Flavoxate-d5 An internal standard for the quantification of flavoxate
  6. GC49098 Olsalazine-13C6 An internal standard for the quantification of olsalazine
  7. GC49097 α-Conotoxin AuIB (trifluoroacetate salt)

    GCCSYPPCFATNPDC

     A conotoxin and an antagonist of α3β4 subunit-containing nAChRs
  8. GC49095 Olanzapine-related Compound B

    奥氮平相关物质B

     A potential impurity found in commercial preparations of olanzapine
  9. GC49094 CAY10781 An NRP-1/VEGF-A interaction inhibitor
  10. GC49093 Safflower Red

    红花黄色素

     A red pigment with diverse biological activities
  11. GC49090 Nilvadipine-d4

    (±)-Nilvadipine-d4

     An internal standard for the quantification of nilvadipine
  12. GC49088 1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE

    1-Octadecanoyl-2-Docosatetraenoyl-sn-glycero-3-Phosphatidylethanolamine, 1-Octadecanoyl-2-Docosatetraenoyl-sn-glycero-3-Phosphoethanolamine, 1-Octadecanoyl-2-Docosatetraenoyl-sn-glycero-3-PE, PE(18:0/22:4), 1-Stearoyl-2-Docosatraenoyl-sn-glycero-3-PE

     A phospholipid
  13. GC49080 CAY10786

    GPR52-IN-43

     A GPR52 antagonist
  14. GC49075 Loxapine-d8

    洛沙平D8

     An internal standard for the quantification of loxapine
  15. GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase
  16. GC49070 Alizapride-13C-d3 (hydrochloride) An internal standard for the quantification of alizapride
  17. GC49069 Biperiden-d5 An internal standard for the quantification of biperiden
  18. GC49063 Emedastine-13C-d3 (fumarate) An internal standard for the quantification of emedastine
  19. GC49059 CP94

    1,2-二乙基-3-羟基吡啶-4(1H)-酮

     An iron chelator
  20. GC49058 DTPA

    二乙烯三胺五醋酸,Diethylenetriaminepentaacetic acid; DTPA

     A cell-impermeable metal chelating agent
  21. GC49056 Dolasetron-d4

    MDL-73147-d4

     An internal standard for the quantification of dolasetron
  22. GC49055 Tebuconazole-d9

    戊唑醇 d9

     An internal standard for the quantification of tebuconazole
  23. GC49054 Oxaprozin-d5

    Oxaprozinum-d5; Wy21743-d5

     An internal standard for the quantification of oxaprozin
  24. GC49047 T-5342126 A TLR4 antagonist
  25. GC49036 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α

    15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α, 15-(6-nitroxyhexanoyl)-Bimatoprost, NCX 470

     A nitric oxide-donating derivative of 17-phenyl trinor prostaglandin F2α
  26. GC49034 1(R)-(Trifluoromethyl)oleyl alcohol An oleic acid analog
  27. GC49024 Palmitic Acid MaxSpec® Standard

    棕榈酸

     A long-chain saturated fatty acid
  28. GC49023 Palmitic Acid-d9 MaxSpec® Standard

    棕榈酸-13,13,14,14,15,15,16,16,16-D9

     A quantitative analytical standard guaranteed to meet MaxSpec identity, purity, stability, and concentration specifications
  29. GC49020 Levomefolate-13C-d3

    L-Methyl Folate-13C-d3, 6S-5-Methyltetrahydrofolate-13C-d3, 6S-5-MTHF-13C-d3

     An internal standard for the quantification of levomefolate
  30. GC49019 BAN ORL 24 (hydrochloride) A nociceptin receptor antagonist
  31. GC49017 8-hydroxy Amoxapine A metabolite of amoxapine
  32. GC49003 (E)-Ajoene

    NSC 614554

     A disulfide with diverse biological activities
  33. GC48999 rac-Aprepitant-d4 An internal standard for the quantification of aprepitant
  34. GC48981 Senktide (trifluoroacetate salt) A potent NK3 receptor agonist
  35. GC48970 MCOPPB (hydrochloride hydrate) An Analytical Reference Standard
  36. GC48969 Withanone

    NSC 179884

     A phytochemical with diverse biological activities
  37. GC62706 Contezolid

    MRX-I

     Contezolid (MRX-I) 是一种新型的恶唑烷酮，用于耐药革兰氏阳性菌引起的皮肤组织感染并发症 (cSSTI) 的抗生素。Contezolid (MRX-I) 可显著降低骨髓移植和单胺氧化酶抑制。
  38. GC62702 RAGE antagonist peptide TFA RAGE antagonist peptide TFA 是一种晚期糖基化终产物 (RAGE) 拮抗剂。RAGE antagonist peptide TFA 可阻断 RAGE 和几个重要配体 HMGB-1，S100P，S100A4 的结合。RAGE antagonist peptide TFA 具有抗肿瘤和抗炎活性。
  39. GC62462 LOX-IN-3

    (2Z)-3-氟-4-(8-喹啉磺酰基)-2-丁烯-1-胺

     LOX-IN-3 是一种具有口服活性的赖氨酰氧化酶 (lysyl oxidase (LOX)) 抑制剂，可用于纤维化，癌症和/或血管生成研究。
  40. GC62458 Rodatristat ethyl

    KAR5585

    Rodatristat ethyl (KAR5585) 是一种首创的,具有口服活性的 tryptophan hydroxylase 1 (TPH1) 抑制剂，具有体外纳摩尔浓度，可降低 5-hydroxytryptamine (5-HT) 的水平并显着降低肺动脉高压 (PAH)，
  41. GC62417 Alniditan dihydrochloride

    阿尼地坦,Alnitidan dihydrochloride

     Alniditan (Alnitidan) dihydrochloride 是一种有效的 5-HT1B 和 5-HT1D 受体激动剂，在 HEK 293 细胞中，对人 5-HT1B 和 人 5-HT1D 受体的 IC50 分别为 1.7 nM 和 1.3 nM。Alniditan dihydrochloride 具有预防偏头痛的作用。
  42. GC62267 Cimetidine sulfoxide

    西咪替丁亚砜; Cimetidine sulphoxide

     Cimetidine sulfoxide (Cimetidine sulphoxide) 是一种 Cimetidine 的亚砜代谢产物。Cimetidine 是一种组胺 H2 受体 (H2-receptor) 拮抗剂，可用于消化性溃疡和上消化道出血的研究。
  43. GC62257 TAT-Gap19 TFA TAT-Gap19 TFA 是一种 Cx 模拟肽，是一种特定的 connexin43 半通道 (Cx43 HC) 抑制剂。TAT-Gap19 TFA 不抑制相应的 Cx43 GJC。TAT-Gap19 TFA 可以透过血脑屏障，减轻小鼠的肝纤维化。
  44. GC62202 PXS-4728A

    BI-1467335

     PXS-4728A 是一种具有口服活性的选择性氨基脲敏感性胺氧化酶 (SSAO) 抑制剂。PXS-4728A 可改善小鼠的慢性阻塞性肺疾病。
  45. GC62199 Vazegepant hydrochloride

    Zavegepant hydrochloride; BHV-3500 hydrochloride

     Vazegepant (BHV-3500) hydrochloride 是一种高度亲和性 CGRP 受体拮抗剂 (hCGRP Ki=0.023 nM)。Vazegepant hydrochloride 是第一种用于偏头痛的鼻用 gepant。Vazegepant hydrochloride 可能有助于有效管理 COVID-19 相关肺部炎症。
  46. GC62146 XST-14 XST-14 是一种有效的，竞争性强且高度选择性的 ULK1 抑制剂，IC50 为 26.6 nM。XST-14 通过减少 ULK1 下游底物的磷酸化来诱导自噬抑制。XST-14 诱导肝细胞癌 (HCC) 细胞凋亡，并具有抗肿瘤作用。
  47. GC19831 SCD1 inhibitor-4 SCD1 inhibitor-4 是一种有效的、具有口服活性的硬脂酰辅酶A 去饱和酶-1 (SCD1) 抑制剂。
  48. GC19824 (±)-Pinocembrin

    松属素,(±)-5,7-Dihydroxyflavanone; NSC 43318

     A flavonoid with diverse biological activities
  49. GC19811 TAK-041

    NBI-1065846

     TAK-041 是一流的、有效的、选择性的小分子 G 蛋白偶联受体 139 (GPR139) 激动剂，EC50 为 22 nM，正在开发用于治疗与精神分裂症相关的认知障碍和阴性症状。
  50. GC19802 Octreotide acetate

    奥曲肽; SMS 201-995

     A somatostatin receptor agonist
  51. GC19799 Selegiline hydrochloride

    盐酸司来吉兰; Deprenyl hydrochloride; (-)-Selegiline hydrochloride; (-)-Deprenyl hydrochloride

     A selective inhibitor of MAO-B

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