5-HT Receptor(5-羟色胺受体)
5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.
Products for 5-HT Receptor
- Cat.No. 产品名称 Information
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GC30206
Roluperidone (CYR-101)
CYR-101; MIN-101; MT-210
A dual antagonist of 5-HT2A and σ2 receptors -
GC30198
Dolasetron Mesylate hydrate
甲磺酸多拉司琼,MDL-73147EF hydrate
A 5-HT3 receptor antagonist -
GC19389
YL0919
YL0919
YL0919 (YL0919) 是一种具有双重活性的口服抗抑郁药,作为高度选择性的 5-HT 摄取阻滞剂和有效的 5-HT1Areceptor 激动剂 (Ki=0.19 nM)。 - GC19354 TG6-10-1 A potent EP2 receptor antagonist
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GC19294
Piboserod
哌波色罗,SB-207266
A selective, potent 5-HT4 receptor antagonist - GC19176 GSK163090 GSK163090 是一种有效的、选择性的和具有口服活性的 5-HT1A/1B/1D 受体拮抗剂,pKi 值分别为 9.4/8.5/9.7。
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GC18244
Eltoprazine (hydrochloride)
1-(2,3-二氢苯并[B][1,4]二氧杂芑-5-基)哌嗪,DU 28853 hydrochloride
A partial agonist of 5-HT1A, 5-HT1B, and 5-HT2B receptors -
GC14343
3,4-dihydro Naratriptan
N-甲基-3-(1,2,3,6-四氢-1-甲基-4-吡啶)-1H-吲哚-5-乙烷磺酰胺,Naratriptan Impurity B
An impurity in the preparation of naratriptan -
GC17488
Trimipramine (maleate)
三甲丙咪嗪马来酸盐
A tricyclic antidepressant -
GC11556
AL 34662
AL 34497
A potent 5-HT2 receptor agonist -
GC14000
6-fluoro-DL-Tryptophan
6-氟-DL-色氨酸,DL-6-Fluorotryptophan,NSC 9364
A serotonin synthesis inhibitor -
GC14940
5-Methoxytryptamine
5-甲氧基色胺
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GC10670
RS 127445 HCl
RS-127445; MT 500; RS127445
5-HT2B receptor antagonist,high affinity -
GC11989
Nortriptyline (hydrochloride)
盐酸去甲替林; Desmethylamitriptyline hydrochloride; Desitriptilina hydrochloride
A tricyclic antidepressant -
GC12885
Imipramine (hydrochloride)
盐酸丙咪嗪
A tricyclic antidepressant -
GC11100
Flibanserin
氟立班丝氨; BIMT-17; BIMT-17BS
A 5-HT1A receptor agonist and 5-HT2A receptor antagonist -
GC12293
Perphenazine
奋乃静
A typical antipsychotic -
GC10743
Cyclobenzaprine HCl
盐酸环苯扎林; MK130 hydrochloride
An Analytical Reference Material -
GC16634
Sumatriptan
舒马曲坦,GR 43175 free base
An agonist of 5-HT1B and 5-HT1D receptors -
GC11844
Pimavanserin
匹莫范色林; ACP-103
A 5-HT2A inverse agonist -
GC14743
WY 45233 succinate
去甲文拉法辛(O-去甲文拉法辛)琥珀酸,O-Desmethylvenlafaxine succinate; Wy-45233 succinate
serotonin and noradrenalin reuptake inhibitor - GC16251 NAD 299 hydrochloride 选择性、高亲和力的 5-HT1A 受体拮抗剂
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GC14392
SB 242084
6-氯-2,3-二氢-5-甲基-N-[6-[(2-甲基-3-吡啶基)氧]-3-吡啶基]-1H-吲哚-1-酰胺盐酸盐
Specific antagonist of 5-HT2C -
GC11384
BTS 54-505 hydrochloride
1-[1-(4-氯苯基)环丁基]-3-甲基丁胺盐酸盐
Potent SNRI,sibutramine metabolite -
GC11176
2-Methyl-5-hydroxytryptamine hydrochloride
2-Methyl-5-hydroxytryptamine hydrochloride; 2-Methylserotonin hydrochloride; 2-Me-HT hydrochloride
2-Methyl-5-hydroxytryptamine hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) 是一种有效的选择性 5-HT3 受体激动剂。 -
GC17826
Tegaserod maleate
马来酸替加色罗; SDZ-HTF-919; HTF-919
A potent 5-HT4 agonist - GC15367 EMDT oxalate EMDT 草酸盐是一种选择性 5-HT6 激动剂,具有抗抑郁作用。
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GC10051
MDL 100907
MDL100907; M 100907
Selective antagonist of the serotonin receptor 5-HT2A - GC15660 SB 399885 hydrochloride A 5-HT6 receptor antagonist
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GC16324
Nefazodone hydrochloride
萘法唑酮盐酸盐,BMY-13754; MJ-13754-1
A serotonin, norepinephrine, and dopamine reuptake inhibitor -
GC13109
Fananserin
法南色林,RP 62203
Fananserin (RP 62203) 是一种口服有效的选择性 5-hydroxytryptamine2 (5-HT2) 受体拮抗剂,对大鼠 5-HT2A 受体的 Ki 值为 0.37 nM。 -
GC11495
Lofepramine
洛非帕明,Lopramine
A tricyclic antidepressant -
GC14583
R 59-022
DKGI-I; Diacylglycerol kinase inhibitor I
A DGK inhibitor -
GC16735
(±)-McN 5652
5-HT uptake inhibitor
-
GC18102
Paroxetine maleate
马来酸帕罗西汀
5-HT uptake inhibitor -
GC17525
AS 19
A 5-HT7 receptor agonist
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GC13883
Ritanserin
利坦丝林,R 55667
A potent 5-HT2A receptor antagonist -
GC13133
Ipsapirone
依普西隆,TVX Q 7821 free base
A partial agonist of serotonin 5-HT1A receptors - GC18013 S 14506 hydrochloride A 5-HT1A receptor agonist
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GC10630
Zimelidine dihydrochloride
齐美利定二盐酸盐
5-HT re-uptake inhibitor
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GC14093
Indatraline hydrochloride
茚达曲林盐酸盐; Lu 19-005
Indatraline hydrochloride (Lu 19-005) 是一种非选择性单胺转运蛋白抑制剂,可阻断神经递质(多巴胺、血清素和去甲肾上腺素)的再摄取,其功效与可卡因相似。 -
GC14035
Citalopram hydrobromide
氢溴酸西酞普兰; (±)-Citalopram hydrobromide; Lu 10-171
A selective serotonin reuptake inhibitor - GC11624 GR 113808 A 5-HT4 antagonist
- GC14805 (S)-WAY 100135 dihydrochloride A 5-HT1A receptor antagonist
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GC13438
SB 224289 hydrochloride
SB-224289A
A 5-HT1B receptor inverse agonist - GC17333 (R)-(+)-8-Hydroxy-DPAT hydrobromide 5-HT1A serotonin receptor agonist
- GC12632 Cyanopindolol hemifumarate 5-HT1A/1B antagonist and β-adrenoceptor antagonist
- GC11984 Isamoltane hemifumarate Isamoltane hemifumarate 是 5-HT1B 受体的选择性拮抗剂,抑制 [125I]ICYP 与大鼠脑膜中 5-HT1B 识别位点的结合,IC50 为 39 nM。
- GC14891 MM 77 dihydrochloride MM 77 dihydrochloride 是一种有效的 5-HT1A 受体的突触后拮抗剂。
- GC17477 5-Nonyloxytryptamine oxalate A potent 5-HT1Dβ receptor agonist