5-HT Receptor(5-羟色胺受体)

5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.

Products for 5-HT Receptor

Cat.No. 产品名称 Information
GC13990 Setiptiline
司普替林; Org-8282
Setiptiline (Org-8282) 是一种血清素受体拮抗剂。
GC11517 SEA0400
2-[4-[(2,5-二氟苯基)甲氧基]苯氧基]-5-乙氧基苯胺,SEA 0400;SEA-0400
A selective inhibitor of the Na⁺/Ca²⁺ exchanger
GC11729 RS 127445
2-氨基-4-(4-氟萘-1-基)-6-异丙基嘧啶,RS-127445; MT 500; RS127445
A 5-HT_2B receptor antagonist
GC16017 Rotigotine hydrochloride
罗替戈汀盐酸盐; N-0923 Hydrochloride
A non-selective dopamine receptor agonist
GC10614 Rotigotine
罗替戈汀; N-0437; N-0923
A non-selective dopamine receptor agonist
GC14167 Quetiapine
喹硫平; ICI204636
Quetiapine是一种5-HT受体激动剂，对人类5-HT1A受体的 pEC₅₀为4.77。Quetiapine是一种多巴胺受体拮抗剂，对人类D2受体的pIC₅₀为6.33。Quetiapine是一种非典型抗精神病药，用于治疗精神分裂症、躁郁症和重度抑郁症。
GC17039 LY 344864
LY344864;LY-344864
A 5-HT_1F receptor antagonist
GC11962 Lu AE58054 Hydrochloride
N-[2-(6-氟-1H-吲哚-3-基)乙基]-3-(2,2,3,3-四氟丙氧基)苄基胺单盐酸盐,Lu AE 58054 Hydrochloride
A 5-HT₆ receptor antagonist
GC12398 Granisetron
格拉司琼; BRL 43694
Granisetron (BRL 43694) 是一种血清素 5-HT3 受体拮抗剂，用作止吐剂，用于治疗化疗后的恶心和呕吐。
GC12782 CP-809101 hydrochloride
2-[(3-氯苯基)甲氧基]-6-(1-哌嗪基)吡嗪盐酸盐,CP809101 hydrochloride;CP 809101 hydrochloride
A potent 5-HT_2C receptor agonist
GC17183 CP-809101
6'-(3-氯苄基氧基)-3,4,5,6-四氢-2H-[1,2']联吡嗪,CP809101;CP 809101
A potent 5-HT_2C receptor agonist
GC10822 Clozapine N-oxide (CNO)
氯氮平N-氧化物
Clozapine N-oxide（CNO）是一种强效的多巴胺拮抗剂，也是一种选择性肌动蛋白M4受体（EC50=11 nM）激动剂。
GC15985 Cariprazine
卡利拉嗪; RGH-188
An atypical antipsychotic
GC12541 Bilobalide
白果内酯; (-)-Bilobalide
A neuroprotective natural product
GC14491 B-HT 920
盐酸他利克索,Domin; Talipexole dihydrochloride
A potent agonist of D₂ receptors
GC14518 Asenapine hydrochloride
阿塞那平盐酸盐
Asenapine hydrochloride 是一种抗精神病药，是一种 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) 和多巴胺 (D2, D3, D4) 受体拮抗剂，Ki 值为 0.03-4.0 nM，作用 5- HT 和多巴胺受体分别为 1.3、0.42、1.1 nM。
GC11166 Alosetron Hydrochloride
盐酸阿洛司琼,GR 68755C;GR 68755;GR 68755X;Lotronex;GR-68755;GR68755
A 5-HT₃ receptor antagonist
GC13654 Alosetron
阿洛司琼; GR 68755; GR 68755X
A 5-HT₃ receptor antagonist
GN10074 Xanthotoxol
花椒毒醇,8-Hydroxypsoralen
A coumarin with diverse biological activities
GN10186 Isocorynoxeine
异去氢钩藤碱; 7-Isocorynoxeine
An alkaloid with diverse biological activities
GN10607 Nuciferine
荷叶碱
An alkaloid with diverse biological activities
GN10680 Puerarin
葛根素
A natural isoflavonoid