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Home >> Signaling Pathways >> Neuroscience >> COX

COX(环氧合酶)

COX (cyclooxygenase) is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane.

Products for  COX

  1. Cat.No. 产品名称 Information
  2. GC32841 Catechin ((+)-Catechin)

    儿茶素; (+)-Catechin; Cianidanol; Catechuic acid

     (+)-Catechin (Cianidanol, Catechinic acid, Catechuic acid) is an antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
  3. GC32640 Pamicogrel (KBT3022)

    帕米格雷; KBT3022

     A COX inhibitor and an antiplatelet agent
  4. GC32030 COX2-IN-1 COX2-IN-1是选择性的，诱导型的COX2抑制剂，IC50值为0.24μM。COX2-IN-1是具有抗炎和止痛活性的抗炎物。
  5. GC32026 Naproxen etemesil (LT-NS 001)

    (S)-2-(甲磺酰)乙基2-(6-甲氧基萘-2-基)丙酯,LT-NS 001; MX 1094

     Naproxen etemesil (LT-NS 001) 是一种亲脂性、非酸性、无活性的萘普生前药，一旦被吸收就会水解成具有药理活性的萘普生。
  6. GC31985 SC58451 SC58451是一个强效的，有选择性的COX-2抑制剂。
  7. GC31967 COX/5-LO-IN-1

    Atreleuton analog

     COX/5-LO-IN-1是cylooxygenase和5-lipoxygenase的抑制剂，用于炎症性和过敏性疾病的研究。
  8. GC31965 Timegadine (SR1368)

    替美加定; SR1368

     Timegadine (SR1368) 是一种新型抗炎剂，被发现是一种有效的、竞争性的环加氧酶 (COX) 和脂加氧酶抑制剂，IC50 范围为 5 nM（洗涤过的兔血小板）至 20 μM（大鼠脑） ) 用于 COX 和 100 μ；M 用于马血小板匀浆的胞质溶胶部分和洗涤过的兔血小板中的脂加氧酶。
  9. GC31962 COX-2-IN-1

    COX-2-IN-1是一个强效的COX-2抑制剂，其IC50值为3.9μM。
  10. GC31960 SC57666

    SC57666是选择性的COX2抑制剂，IC50值为26nM。
  11. GC31956 Tilmacoxib (JTE522)

    替马考昔; JTE522; JTP19605; RWJ57504

     Tilmacoxib (JTE522) (JTE522) 是一种高度选择性、时间依赖性和不可逆的人 COX-2 抑制剂，在酶试验中 IC50 为 85 nM。
  12. GC31943 Methyl Salicylate (Wintergreen oil)

    水杨酸甲酯,Wintergreen oil

     Methyl salicylate (Betula oil, Gaultheria oil, Methyl 2-hydroxybenzoate, Natural wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. It is an agonist for TRPA1 and TRPV1.
  13. GC31835 S-2474 S-2474是COX-2和5-lipoxygenase的抑制剂，在人完整的细胞中，对COX-2和COX-1的IC50值分别为11nM和27μM，为一种非甾体抗炎药。
  14. GC31826 Thioflosulide (L-745337)

    L-745337

     Thioflosulide (L-745337) (L-745337) 是一种选择性 cyclooxygenase-2 (COX2) 抑制剂，IC50 为 2.3 nM，具有抗炎活性。
  15. GC31818 Flosulide (ZK 38997)

    氟舒胺,ZK 38997; CGP 28238

     Flosulide (ZK 38997) 是一种有效的选择性 COX-2 抑制剂，用于治疗炎症性疾病。
  16. GC31813 RWJ 63556 RWJ63556是一种可口服的COX-2selective/5-lipoxygenase抑制剂，具有抗炎活性。
  17. GC31749 Columbin

    古伦宾

     A diterpenoid furanolactone with diverse biological activities
  18. GC31737 Metamizole sodium hydrate

    安乃近水合物

     Metamizole (Dipyrone) sodium hydrate is a potent inhitior of cyclooxygenase (COX) with strong analgesic as well as antipyretic and spasmolytic properties.
  19. GC31707 Chebulagic acid

    诃子鞣酸

     A polyphenol with diverse biological activities
  20. GC31706 Ginsenoside Rg5

    人参皂甙 Rg5

     A ginsenoside with diverse biological activities
  21. GC31693 Adelmidrol

    阿地米屈

     Adelmidrol is an analogue of palmitoylethanolamide (PEA) with anti-inflammatory activities.
  22. GC31440 Syringaldehyde

    丁香醛

     A polyphenol with diverse biological activities
  23. GC30610 LY 178002

    LY178002是一种有效的5-lipoxygenase，phospholipaseA2抑制剂，对5-lipoxygenase的IC50值为0.6μM，能够抑制人多形核白细胞产生LTB4，同时可相对较弱地抑制cyclooxygenase的活性。
  24. GC30027 S-(+)-Marmesin ((+)-Marmesin)

    异紫花前胡内酯,(+)-Marmesin; (S)-Marmesin

     A coumarin with anticancer activity
  25. GC19353 TFAP

    N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide

     A selective COX-1 inhibitor
  26. GC18427 CAY10452

    塞来昔布杂质3

     A non-apoptotic, selective COX-2 inhibitor
  27. GC18369 Cimicoxib

    UR-8880

     A selective inhibitor of COX-2
  28. GC17306 N-tert-butyl-α-Phenylnitrone

    N-叔丁基-α-苯基硝酮

     A spin trap
  29. GC14820 (S)-Naproxen

    萘普生; (S)-Naproxen

     An NSAID and COX inhibitor
  30. GC10335 Valeroyl Salicylate

    戊酰基水杨酸,2-Valeryloxybenzoic Acid

     A selective, irreversible inhibitor of COX-1
  31. GC16153 6-methoxy Naphthalene Acetic Acid

    6-甲基萘乙酸,6-MNA

     A non-selective COX inhibitor
  32. GC14777 Indomethacin N-octyl amide Indomethacin with enhanced selectivity for COX-2
  33. GC14999 O-Acetyl Salicylhydroxamic Acid

    AcSHA,O-ASHA

     An irreversible, non-selective inhibitor of COX-1 and COX-2
  34. GC13132 FR122047 (hydrate) selective inhibitor of COX-1
  35. GC10611 N-(4-acetamidophenyl)-Indomethacin amide

    N-4AIA

     Potent and selective reversible inhibitor of COX-2
  36. GC15959 N-(3-pyridyl)-Indomethacin amide

    N-3PyIA

     Potent and selective reversible inhibitor of COX-2
  37. GC17980 N-(2-phenylethyl)-Indomethacin amide

    N-2PIA

     A selective, reversible inhibitor of COX-2
  38. GC12229 Eicosatetraynoic Acid

    花生四烯酸,ETYA

     A nonspecific inhibitor of cyclooxygenases and lipoxygenases
  39. GC18022 (S)-Flurbiprofen

    (S)-氟比洛芬,Esflurbiprofen

     The COX-active enantiomer of flurbiprofen
  40. GC14847 Psoralidin

    补骨脂定

     A furanocoumarin with anti-cancer activity
  41. GC15372 N-(3-hydroxyphenyl)-Arachidonoyl amide

    3-HPAA

     An irreversible COX-2 inhibitor
  42. GC16440 N-acetyl-2-carboxy Benzenesulfonamide A COX-1/COX-2 inhibitor
  43. GC18010 Ibufenac

    4-异丁基苯乙酸; Dytransin

     A non-selective COX inhibitor
  44. GC15338 8,11,14-Eicosatriynoic Acid

    8,11,14-ETI

     A cyclooxygenase and lipoxygenase inhibitor
  45. GC13402 Tryptanthrin

    色胺酮,NSC 349447

     An alkaloid with diverse actions
  46. GC12719 Indomethacin heptyl ester A potent, non-selective COX-2 inhibitor
  47. GC16428 Tolmetin (sodium salt hydrate)

    痛灭定

     A non-selective NSAID
  48. GC11203 ZLJ-6 Dual inhibitor of cyclooxygenase/5-lipoxygenase
  49. GC14302 9,12-Octadecadiynoic Acid

    Ro 3-1314

     An inhibitor of both COX and lipoxygenase
  50. GC13042 Inotilone

    (2E)-2-[(3,4-二羟基苯基)亚甲基]-5-甲基-3(2H)-呋喃酮

     A COX-2 inhibitor
  51. GC14013 Losartan Carboxaldehyde

    氯沙坦甲醛,DuP-167|EXP3179

     A losartan metabolite with anti-inflammatory actions

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