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Home >> Signaling Pathways >> Neuroscience >> Dopamine Receptor

Dopamine Receptor(多巴胺受体)

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products for  Dopamine Receptor

  1. Cat.No. 产品名称 Information
  2. GC16686 U 99194 maleate D3 antagonist
  3. GC15792 CY 208-243

    (-)-(6AR,12BR)-4,6,6A,7,8,12Β-六氢-7-甲基吲哚[4,3-A]菲啶

     CY 208-243 是一种选择性多巴胺 D1 受体激动剂，具有抗帕金森病活性。
  4. GC16903 GR 103691 A dopamine D3 receptor antagonist
  5. GC17634 PD 168077 maleate A dopamine D4 receptor agonist
  6. GC17877 (-)-Quinpirole hydrochloride

    (-)-LY 171555

     (-)-Quinpirole hydrochloride ((-)-LY 171555) 是一种多巴胺 D2/D3 受体的高亲和力激动剂。
  7. GC11602 Piribedil dihydrochloride

    盐酸吡贝地尔；盐酸双哌嘧啶；盐酸泰舒达

     A dopamine receptor agonist
  8. GC15619 L-741,626 A dopamine D2 receptor antagonist
  9. GC10892 SCH 23390 hydrochloride

    R-(+)-SCH-23390 hydrochloride

     SCH 23390 hydrochloride 是一种高效的选择性多巴胺 D1 样受体拮抗剂，对 D1 和 D5 多巴胺受体亚型的 K(i) 分别为 0.2 和 0.3 nM。
  10. GC15606 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride dopamine uptake and transport inhibitor
  11. GC12641 3-CPMT dopamine uptake inhibitor
  12. GC14822 Remoxipride hydrochloride

    瑞莫必利盐酸盐

     An atypical antipsychotic
  13. GC12870 (+)-UH 232 maleate

    顺-(+)-5-甲氧基-1-甲基-2-(二正丙基氨基)萘满马来酸

     D2 antagonist
  14. GC14311 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride dopamine release inhibitor
  15. GC16916 7-Hydroxy-PIPAT maleate D3 receptor agonist
  16. GC16574 7-Hydroxy-DPAT hydrobromide A dopamine D3 receptor agonist
  17. GC11945 BTCP maleate dopamine reuptake inhibitor
  18. GC15856 3'-Fluorobenzylspiperone maleate

    ligand for the D2 receptor
  19. GC13156 (+)-AJ 76 hydrochloride Dopamine receptor antagonist
  20. GC16049 AMI-193

    螺哌丙苯,AMI-193

     AMI-193 (AMI-193) 是一种有效的、选择性的 5-HT2 和多巴胺 D2 受体拮抗剂，Kis 分别为 2 nM 和 3 nM。
  21. GC12456 GBR 12783 dihydrochloride GBR 12783 dihydrochloride 是一种特异性、有效和选择性的多巴胺摄取抑制剂，抑制大鼠和小鼠纹状体突触体对 [3H] 多巴胺的摄取，IC50 分别为 1.8 nM 和 1.2 nM。
  22. GC12179 GBR 13069 dihydrochloride dopamine uptake inhibitor
  23. GC14865 RuBi-Dopa dopamine receptor activator
  24. GC15326 Flupenthixol dihydrochloride

    盐酸氟哌噻吨,Flupenthixol dihydrochloride

     Flupentixol 是一种具有口服活性的 D1/D2 多巴胺受体拮抗剂和新型 PI3K 抑制剂（PI3Kα；IC50=127 nM）。
  25. GC17075 NPEC-caged-dopamine Dopamine receptor agonist
  26. GC16267 6-Hydroxydopamine hydrobromide

    6-羟基多巴胺氢溴酸盐; 6-Hydroxydopamine hydrobromide; 6-OHDA hydrobromide

     6-Hydroxydopamine hydrobromide (6-OHDA) 是儿茶酚胺、多巴胺和去甲肾上腺素的结构类似物，对儿茶酚胺能神经元发挥毒性作用。
  27. GC13573 Nomifensine

    诺米芬辛; (±)-Nomifensin

     An inhibitor of norepinephrine and dopamine reuptake
  28. GC17890 LE 300 A dopamine D1-like and 5-HT2A receptor antagonist
  29. GC17192 Quinelorane hydrochloride

    LY163502

     Quinelorane hydrochloride (LY163502) 是一种有效的多巴胺 D3/D2 受体激动剂。
  30. GC14048 SKF 38393 hydrobromide

    (±)-SKF-38393 hydrobromide

     A partial agonist of dopamine D1-like receptors
  31. GC10349 (RS)-(±)-Sulpiride

    舒必利

     An atypical antipsychotic
  32. GC13931 Bromocriptine mesylate

    甲磺酸溴隐亭; CB-154

     A dopamine receptor agonist
  33. GC13853 GBR 12935 dihydrochloride An inhibitor of dopamine uptake
  34. GC14657 Rotundine

    罗通定; (-)-Tetrahydropalmatine; L-Tetrahydropalmatine

     An antinociceptive alkaloid
  35. GC10441 Cabergoline

    卡麦角林; FCE-21336

     A potent and selective dopamine D2 receptor agonist
  36. GC11028 Dopamine HCl

    盐酸多巴胺,ASL279

     An endogenous catecholamine
  37. GC10144 Domperidone

    多潘立酮; R33812

     A dopamine D2 receptor antagonist
  38. GC15107 Clomipramine HCl

    盐酸氯米帕明; Chlorimipramine hydrochloride; G-34586 hydrochloride; NSC-169865 hydrochloride

     A tricyclic antidepressant
  39. GC14216 Chlorpromazine HCl

    盐酸氯丙嗪

     Chlorpromazine HCl是一种口服有效的、可透过血脑屏障的吩噻嗪类抗精神病药，能够有效抑制D2多巴胺受体和5-HT2A，具有很强的镇静作用。
  40. GC15546 Alizapride HCl

    盐酸阿立必利

     A dopamine D2 receptor antagonist
  41. GC14759 Fenoldopam

    非诺多泮; SKF 82526

     An agonist of dopamine D1A and D1B receptors
  42. GC15470 Levosulpiride

    左舒必利; RV-12309; S-(-)-Sulpiride

     左舒必利 (RV-12309) 是舒必利的 (S)-对映异构体，是一种 D2 受体拮抗剂，是苯甲酰胺类的非典型抗精神病药物。
  43. GC16783 Pramipexole 2HCl Monohydrate

    普拉克索盐酸盐水合物

     Pramipexole 2HCl Monohydrate 是一种选择性和血脑屏障 (BBB) 渗透性多巴胺 D2 型受体激动剂，对 D2 型受体、D2、D3 和 D4 受体的 Kis 分别为 2.2 nM、3.9 nM、0.5 nM 和 1.3 nM .
  44. GC11960 Pramipexole

    普拉克索

     Pramipexole 是一种选择性和血脑屏障 (BBB) 渗透性多巴胺 D2 型受体激动剂，对 D2 型受体、D2、D3 和 D4 受体的 Kis 分别为 2.2 nM、3.9 nM、0.5 nM 和 1.3 nM。
  45. GC10105 Amantadine HCl

    盐酸金刚烷胺; 1-Adamantanamine hydrochloride; 1-Adamantylamine hydrochloride; 1-Aminoadamantane hydrochloride

     An NMDA receptor antagonist and antiviral agent
  46. GC15754 WAY-100635 Maleate A serotonin 5-HT1A antagonist
  47. GC13031 Trifluoperazine 2HCl

    盐酸三氟拉嗪；甲哌氟丙嗪；三氟吡拉嗪

     An anti-adrenergic and anti-dopaminergic agent
  48. GC11462 Ropinirole HCl

    盐酸罗匹尼罗; SKF 101468 hydrochloride

     A dopamine D2 receptor agonist
  49. GC16615 Pergolide mesylate

    甲磺酸培高利特; Pergolide methanesulfonate; LY127809

     A dopamine D1 and D2 receptor agonist
  50. GC17600 PD128907 HCl A potent D3 receptor agonist
  51. GC10808 Droperidol

    氟哌啶; Dehydrobenzperidol

     A dopamine D2 and D4 receptor antagonist

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