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Home >> Signaling Pathways >> Neuroscience >> Dopamine Receptor

Dopamine Receptor(多巴胺受体)

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products for  Dopamine Receptor

  1. Cat.No. 产品名称 Information
  2. GC16229 Azaperone

    阿扎哌隆,R-1929

     An Analytical Reference Standard
  3. GC17593 Lurasidone HCl

    盐酸鲁拉西酮; SM-13496 Hydrochloride

     An atypical antipsychotic
  4. GC16891 Quetiapine Fumarate

    富马酸喹硫平

     An antagonist of diverse neurological receptors
  5. GC11182 LY404039

    (1R,4S,5S,6S)-4-氨基-2-硫杂双环[3.1.0]己烷-4,6-二甲酸2,2-二氧化物

     An agonist of mGluR2 and mGluR3
  6. GC10799 Iloperidone hydrochloride

    盐酸伊潘立酮; HP 873 hydrochloride

     An atypical antipsychotic
  7. GC11186 Brexpiprazole

    依匹哌唑; OPC-34712

     A serotonin and dopamine receptor modulator
  8. GC10117 Aripiprazole

    阿立哌唑; OPC-14597

     An atypical antipsychotic
  9. GC12610 Amisulpride

    氨磺必利; DAN 2163

     A dopamine D2 and D3 and 5-HT2B, 5-HT7, and 5-HT7A receptor antagonist
  10. GC12495 Olanzapine

    奥氮平; LY170053

     An atypical antipsychotic
  11. GC17760 Clozapine

    氯氮平; HF 1854

     An atypical antipsychotic
  12. GC11506 Haloperidol hydrochloride

    氟哌啶醇盐酸盐

     A typical antipsychotic and dopamine D2-like receptor antagonist
  13. GC17599 Haloperidol

    氟哌啶醇

     Haloperidol是一种典型的抗精神病药和多巴胺D2样受体拮抗剂，也是离子通道抑制剂，可抑制多种离子通道，如G蛋白激活的内向整流钾通道、钙激活钾通道、HERG和HEAG钾通道以及L、N和P型钙通道。
  14. GC17184 Ambrisentan

    安倍生坦; BSF 208075; LU 208075

     An ETA receptor antagonist
  15. GC17769 Sitaxentan sodium

    西他生坦钠,IPI 1040 sodium; TBC11251 sodium

     A potent ETA receptor antagonist
  16. GC14714 Bupropion hydrochloride

    盐酸氨非他酮; Amfebutamone hydrochloride

     An Analytical Reference Material
  17. GC13322 Vanoxerine

    GBR 12909; I893

     Vanoxerine (GBR-12909) 是一种竞争性、强效和高度选择性的多巴胺再摄取抑制剂 (Ki=1 nM)。
  18. GC17741 Vanoxerine dihydrochloride

    伐诺司林二盐酸盐,GBR-12909 dihydrochloride; I893 dihydrochloride

     An inhibitor of dopamine uptake
  19. GC15312 Chlorprothixene

    氯普噻吨

     A dopamine D2 receptor antagonist
  20. GC14160 Blonanserin

    布南色林; AD-5423

     A dopamine and serotonin receptor antagonist
  21. GC11977 Thioridazine HCl

    盐酸硫利达嗪；盐酸硫代利哒；甲硫达嗪盐酸盐；甲硫哒嗪盐酸盐

     A typical antipsychotic
  22. GC12986 Risperidone

    利培酮; R 64 766

     An atypical antipsychotic
  23. GC10112 Paliperidone

    9-羟基利培酮; 9-Hydroxyrisperidone

     An atypical antipsychotic
  24. GC15095 Levodopa

    左旋多巴; Levodopa; 3,4-Dihydroxyphenylalanine

     A dopamine precursor
  25. GC15463 Iloperidone

    伊潘立酮; HP 873

     An atypical antipsychotic
  26. GC11521 Ziprasidone HCl

    盐酸齐拉西酮; CP-88059 hydrochloride

     An atypical antipsychotic
  27. GC13627 Ziprasidone hydrochloride monohydrate

    盐酸齐拉西酮水合物; CP 88059 hydrochloride monohydrate

     An atypical antipsychotic
  28. GC11020 Ziprasidone

    齐拉西酮; CP-88059

     齐拉西酮 (CP-88059) 是一种口服活性抗精神病药，是一种 5-HT 和多巴胺受体拮抗剂的组合。
  29. GC16270 WAY-100635 maleate salt

    WAY 100635 maleate salt; WAY100635 maleate salt

     A serotonin 5-HT1A antagonist
  30. GC10108 WAY-100635

    WAY 100635; WAY100635

     A serotonin 5-HT1A antagonist
  31. GC16017 Rotigotine hydrochloride

    罗替戈汀盐酸盐; N-0923 Hydrochloride

     A non-selective dopamine receptor agonist
  32. GC10614 Rotigotine

    罗替戈汀; N-0437; N-0923

     A non-selective dopamine receptor agonist
  33. GC14167 Quetiapine

    喹硫平; ICI204636

     Quetiapine是一种5-HT受体激动剂，对人类5-HT1A受体的 pEC50为4.77。Quetiapine是一种多巴胺受体拮抗剂，对人类D2受体的pIC50为6.33。Quetiapine是一种非典型抗精神病药，用于治疗精神分裂症、躁郁症和重度抑郁症。
  34. GC13625 Pramipexole dihydrochloride

    盐酸普拉克索

     A dopamine D2S, D2L, D3, and D4 receptor agonist
  35. GC11097 MPTP hydrochloride

    1-甲基-4-苯基-1,2,3,6-四氢吡啶盐酸盐,MPTP

     MPTP（1-甲基-4-苯基-1,2,3,6-四氢吡啶）是一种神经毒性物质，它是MPP+的前体，对多巴胺能神经元有毒，并导致帕金森病。
  36. GC16249 Metoclopramide

    胃复安

     Metoclopramide（胃复安）是一种有效的5-HT3和多巴胺D2受体拮抗剂，IC50 值分别为308nM和483nM。
  37. GC14252 (–)-Stepholidine

    左旋千金藤啶碱,Stepholidine;(-)-Stepholidine;L-SPD

     A dopamine receptor antagonist and 5-HT1A partial agonist
  38. GC10822 Clozapine N-oxide (CNO)

    氯氮平N-氧化物

     Clozapine N-oxide（CNO）是一种强效的多巴胺拮抗剂，也是一种选择性肌动蛋白M4受体（EC50=11 nM）激动剂。
  39. GC15985 Cariprazine

    卡利拉嗪; RGH-188

     An atypical antipsychotic
  40. GC14491 B-HT 920

    盐酸他利克索,Domin; Talipexole dihydrochloride

     A potent agonist of D2 receptors
  41. GC14518 Asenapine hydrochloride

    阿塞那平盐酸盐

     Asenapine hydrochloride 是一种抗精神病药，是一种 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) 和多巴胺 (D2, D3, D4) 受体拮抗剂，Ki 值为 0.03-4.0 nM，作用 5- HT 和多巴胺受体分别为 1.3、0.42、1.1 nM。
  42. GN10513 Tetrahydroberberine,THB

    四氢小檗碱; Canadine

     An isoquinoline alkaloid with diverse biological activities
  43. GN10607 Nuciferine

    荷叶碱

     An alkaloid with diverse biological activities
  44. GN10740 Tetrahydropalmatine

    延胡索乙素; DL-Tetrahydropalmatine

     四氢巴马汀具有镇痛作用。

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