Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC43300 Combretastatin A1
康普瑞汀A-1
An inhibitor of microtubule assembly
GC43286 CMPD101 A GRK2 and GRK3 inhibitor
GC43265 Chromomycin A2
色霉素A2
An antibacterial and anticancer aureolic acid
GC43250 Cho-Arg (trifluoroacetate salt) A steroid-based cationic lipid
GC43239 Chk2 Inhibitor
SC-203885
A Chk2 inhibitor
GC43230 Ceramides (non-hydroxy) Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase.
GC43229 Ceramide Phosphoethanolamines (bovine) Ceramide phosphoethanolamine (CPE) is an analog of sphingomyelin that contains ethanolamine rather than choline as the head group.
GC43219 Cdk2 Inhibitor II
Cyclin-dependent kinase 2 Inhibitor II, SC-221409
Selective and potent inhibitor of Cdk2
GC43217 CDK/CRK Inhibitor
Cdk7 Inhibitor IV, Cyclin-dependent kinase 7 Inhibitor IV, Cyclin-dependent kinase/CDK-related kinase Inhibitor, RGB-286147
A CDK/CRK-specific kinase inhibitor
GC43206 CAY10732 CAY10732是一种检测一氧化碳的荧光探针。
GC43184 CAY10622 A ROCK1 and ROCK2 inhibitor
GC43154 CAY10443
(S)Indan1yl 3,4dichlorobenzylcarbamate
A cytochrome c-dependent inducer of apoptosis
GC43150 CAY10406 A trifluoromethyl analog of a selective caspase inhibitor
GC43146 Caspase-9 Inhibitor III (trifluoroacetate salt)
Ac-LEHD-CMK
A caspase-9 inhibitor
GC43144 Carfilzomib Impurity 13 (hydrochloride) A potential impurity found in commercial carfilzomib preparations
GC43139 Capsanthin
辣椒红
A carotenoid with diverse biological activities
GC43135 Cambendazol
坎苯达唑
An anthelmintic agent
GC42997 Butyrolactone I
丁酸内酯I,Olomoucin
A Cdk1 inhibitor
GC42969 bpV(phen) (potassium hydrate)
Bisperoxovanadium(phen), Potassium Bisperoxo(1,10phenanthroline) oxovanadate (V)
An inhibitor of phosphatases
GC42961 BODIPY 558/568 C12
Red C12

A fluorescent probe for lipid droplets
GC42960 BODIPY 505/515
4,4-二氟-1,3,5,7-四甲基-4-硼-3A,4A-二氮杂-S-茚烯

BODIPY 505/515是一种亲脂性荧光染料，发出的荧光被广泛用于标记脂质滴（激发/发射：505/515纳米）。
GC42959 BODIPY 493/503
4,4-二氟-1,3,5,7,8-五甲基-4-硼-3A,4A-二氮杂-S-茚烯,Pyrromethene 546; BDP 493/503 lipid stain

BODIPY 493/503是一种亲脂性荧光染料，发出明亮的绿色荧光，被广泛用于标记脂质滴（激发/发射：493/503纳米）。
GC42942 bis-ANS (potassium salt)
4,4'-二苯胺基-1,1'-联萘-5,5'-二磺酸二钾盐,4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid

一种高亲和力非共价外源荧光染料
GC42936 Biotin Tripeptide-1
生物素酰基甘氨酰组氨酰赖氨酸
An ECM peptide conjugated to biotin
GC42933 Binucleine 2 An inhibitor of Drosophila Aurora B kinase
GC42897 BAY 61-3606 (hydrochloride) A Syk inhibitor
GC42788 Aminopeptidase N Inhibitor Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM).
GC42747 Afuresertib (hydrochloride)
GSK2110183 hydrochloride
A pan-Akt inhibitor
GC42721 Ac-YVAD-CMK
Caspase-1 Inhibitor II
Ac-YVAD-CMK 是一种选择性不可逆的 caspase-1 抑制剂 (Ki=0.8nM)，可阻止促炎细胞因子 IL-1β 的激活。
GC42719 Ac-WEAD-pNA (trifluoroacetate salt)
Ac-Trp-Glu-Ala-Asp-pNA, Ac-Trp-Glu-Ala-Asp-p-nitroanilide, Caspase-1 and Caspase-4 Chromogenic Substrate
A colorimetric caspase-1 and caspase-4 substrate
GC42718 Ac-VEID-CHO (trifluoroacetate salt)
Ac-Val-Glu-Ile-Asp-CHO
A caspase-6 inhibitor
GC42716 Ac-VDVAD-pNA (trifluoroacetate salt)
Ac-Val-Asp-Val-Ala-Asp-pNA, Caspase-2 Chromogenic Substrate, acetyl-Val-Asp-Val-Ala-Asp-p-nitroanilide, acetyl-VDVAD-p-nitroanilide
A colorimetric caspase-2 substrate
GC42715 Ac-VDVAD-CHO (trifluoroacetate salt)
Ac-Val-Asp-Val-Ala-Asp-CHO
A caspase-2, caspase-3, and caspase-7 inhibitor
GC42709 Ac-LEVD-CHO (trifluoroacetate salt)
Ac-Leu-Glu-Val-Asp-CHO, Caspase-4 Inhibitor I
A caspase-4 inhibitor
GC42708 Ac-LEHD-AFC (trifluoroacetate salt)
N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase-9 substrate (Fluorogenic)
A caspase-4, -5, and -9 fluorogenic substrate
GC42706 Ac-IEPD-AMC (trifluoroacetate salt)
Acetyl-Ile-Glu-Pro-Asp-7-amino-4-Methylcoumarin, Ac-Ile-Glu-Pro-Asp-AMC
A fluorogenic substrate for granzyme B
GC42701 Acetyl Tetrapeptide-3
乙酰基四肽-3
A biomimetic peptide
GC42689 Ac-DNLD-AMC
Ac-Asp-Asn-Leu-Asp-MCA, N-Acetyl-Asp-Asn-Leu-Asp-7-amido-Methylcoumarin, Caspase-3 Substrate
A fluorogenic caspase-3 substrate
GC42688 Ac-DMQD-CHO (trifluoroacetate salt)
Ac-Asp-Met-Gln-Asp-CHO, Caspase-3 Inhibitor
An inhibitor of caspase-3
GC42687 Ac-DMQD-AMC (trifluoroacetate salt)
Ac-Asp-Met-Gln-Asp-AMC, Ac-Asp-Met-Gln-Asp-7-amino-4-methylcoumarin
A fluorogenic substrate for caspase-3
GC42684 Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt)
A sensitive substrate for proteinase 3
GC42683 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp A sensitive substrate for neutrophil elastase
GC42665 AAF-CMK (trifluoroacetate salt)
NAlaAlaPheCMK, Tripeptidyl Peptidase Inhibitor II
An inhibitor of TPPII
GC42616 7-oxo Staurosporine
BMY 41950, RK-1409
An antibiotic with diverse biological activities
GC42610 7-hydroxy Pestalotin
LL-P880β
A fungal metabolite
GC42586 6α-hydroxy Paclitaxel
6-羟基泰素
A metabolite of paclitaxel
GC42548 5-hydroxy Saxagliptin (hydrochloride) A major active metabolite of saxagliptin
GC42449 4-Methylumbelliferyl-α-L-Iduronide (free acid)
ALPHA-L-四羟基环氧戊酸-4-甲基伞形酯
A fluorogenic substrate for α-L-iduronidase
GC42239 3,6-diacetoxy Phthalonitrile
1,4-二乙酰基-2,3-二氰苯
A fluorescent pH probe
GC42161 2H-Cho-Arg (trifluoroacetate salt) A steroid-based cationic lipid