Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC40482 Curvulin
2-乙酰基-3,5-二羟基苯乙酸乙酯
An inhibitor of microtubule assembly
GC40476 Allethrin
丙烯菊酯
A pyrethroid insecticide
GC40448 12(S)-HETE
12(S)-Hydroxyeicosatetraenoic Acid
The predominant lipoxygenase product of mammalian platelets
GC40296 D-erythro-MAPP
D-e-MAPP
An inhibitor of alkaline ceramidase
GC40265 Pheleuin A pyrazinone
GC34692 NU6140 A Cdk2 inhibitor
GC40256 p-APMSF (hydrochloride)
(4-脒苯基)甲磺酰氟盐酸盐
An irreversible inhibitor of serine proteases
GC40202 7α-hydroxy Cholesterol-d7
7ALPHA-羟基胆固醇-25,26,26,26-27,27,27-D7,7α-hydroxycholesterol-d7
An internal standard for the quantification of 7α-hydroxy cholesterol
GC40164 Ac-IETD-CHO (trifluoroacetate salt)
Caspase-8 Inhibitor
A caspase-8 inhibitor
GC40162 Ac-VEID-pNA (trifluoroacetate salt)
Ac-Val-Glu-Ile-Asp-pNA, Ac-Val-Glu-Ile-Asp-p-nitroanilide, Caspase-6 Chromogenic Substrate
A colorimetric caspase-6 substrate
GC40155 Biotin-DEVD-CHO (trifluoroacetate salt)
Biotin-Asp-Glu-Val-Asp-CHO
A biotinylated caspase-3 and -7 inhibitor
GC40154 Ac-ESMD-CHO (trifluoroacetate salt)
Ac-Glu-Ser-Met-Asp-CHO
An inhibitor of caspase-3 maturation
GC40153 Z-YVAD-AFC (trifluoroacetate salt)
Z-Tyr-Val-Ala-Asp-AFC, Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin, Z-YVAD-7-amino-4-trifluoromethylcoumarin
A fluorogenic substrate for caspase-1
GC40152 Ac-IEPD-pNA (trifluoroacetate salt)
Ac-Ile-Glu-Pro-Asp-p-nitroanilide, Caspase-8 Chromogenic Substrate, Granzyme B Substrate VIII
A colorimetric granzyme B and caspase-8 substrate
GC40151 Z-VAD-AMC (acetate)
Z-Val-Ala-Asp-AMC, Z-Val-Ala-Asp-7-amino-4-methylcoumarin
A caspase-1 fluorogenic substrate
GC40150 Z-VEID-AFC (trifluoroacetate salt)
Z-Val-Glu-Ile-Asp-AFC, Z-Val-Glu-Ile-Asp-7-amino-4-trifluormethylcoumarin
A fluorogenic substrate for caspase-6
GC40149 Boc-AEVD-CHO (trifluoroacetate salt)
Boc-Ala-Glu-Val-Asp-CHO
An inhibitor of caspase-8
GC40145 (S)-Laudanosine
(+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045
The (S) enantiomer of laudanosine
GC40125 Z-VA-DL-D(OMe)-FMK (trifluoroacetate salt)
Caspase-1 Inhibitor V, Z-VAD-FMK, Z-VAD(OMe)-FMK, Z-Val-Ala-DL-Asp(OMe)-Fluoromethyl Ketone
A pan-caspase inhibitor
GC40124 Ac-WEAD-AMC (trifluoroacetate salt)
Ac-Trp-Glu-Ala-Asp-AMC
A caspase-1 and caspase-4 fluorogenic substrate
GC40123 Ac-AAVALLPAVLLALLAP-VAD-CHO (trifluoroacetate salt)
Caspase Inhibitor II, Ac-AAVALLPAVLLALLAP-VAD-aldehyde, Ac-AAVALLPAVLLALLAPVAD-CHO
A non-selective caspase inhibitor
GC40122 Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt)
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO, Ac-AAVALLPAVLLALLAP-DEVD-aldehyde, Ac-AAVALLPAVLLALLAPDEVD-CHO, Caspase-3 Inhibitor I, DEVD-CHO-CPP 32
A caspase-3 inhibitor
GC40121 (Z-DEVD)2-Rh 110 (trifluoroacetate salt)
(Z-Asp-Glu-Val-Asp)2-Rhodamine 110
A fluorogenic substrate for caspase-3
GC40120 Mca-LEVDGW-K(Dnp)-NH2 (trifluoroacetate salt)
Mca-Leu-Glu-Val-Asp-Gly-Trp-Lys(Dnp)-NH2
A fluorogenic substrate for caspase-4
GC40119 Z-YVADLD-FMK (trifluoroacetate salt)
Z-Tyr-Val-Ala-Asp-Leu-Asp-FMK
A peptide
GC40118 Ac-AAVALLPAVLLALLAP-IETD-CHO (trifluoroacetate salt)
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO, Caspase-8 Inhibitor I
An inhibitor of caspase-8 and granzyme B
GC40094 all-trans Retinoic Acid-d5
atRA-d5, RA-d5, Vitamin A Acid-d5
An internal standard for the quantification of all-trans retinoic acid
GC40085 Pazopanib-d6
培唑帕尼-d6,GW786034-d6
An internal standard for the quantification of pazopanib
GC40060 Blasticidin A
灰瘟素A,(+)-Blasticidin A
A bacterial metabolite
GC40048 MPS1/TTK Inhibitor An inhibitor of Mps1/TTK
GC40044 Zymostenol
Δ8-Cholesterol
A precursor of cholesterol
GC40036 MHAPC-Chol A cationic cholesterol
GC40021 LysoFP-NO2 A turn-on fluorescent probe for carbon monoxide
GC40016 Ganglioside GM2 Mixture (sodium salt)
单唾液酸神经节苷脂GM2; GM2; Monosialoganglioside GM2
A mixture of ganglioside G_M2
GC40009 Bostrycin
Rhodosporin
An anthraquinone with diverse biological activities
GC34374 BAY-1895344 hydrochloride An ATR inhibitor
GC34303 Taltobulin hydrochloride (HTI-286 hydrochloride) An inhibitor of microtubule polymerization
GC34300 AR-13324 analog mesylate AR-13324类似物甲磺酸盐是AR-13324的类似物。
GC34297 PF-2771 PF-2771是一种选择性的着丝粒蛋白E(CENP-E)抑制剂，IC50值为16.1nM，具有抗肿瘤活性。
GC34159 Ilorasertib (ABT-348)
ABT-348
A multi-kinase inhibitor
GC34135 Taltobulin trifluoroacetate (HTI-286 trifluoroacetate)
HTI-286 trifluoroacetate; SPA-110 trifluoroacetate
An inhibitor of microtubule polymerization
GC34109 Tirbanibulin Mesylate (KX2-391 (Mesylate))
KX2-391 Mesylate; KX01 Mesylate
A Src kinase inhibitor
GC34102 BNC105 An inhibitor of tubulin polymerization
GC34094 Mycro 3 Mycro 3 is a potent and selective inhibitor of c-Myc in whole cell assays. Mycro 3 also shows weak inhibitory activity against AP-1.
GC34073 Empesertib (BAY 1161909)
BAY 1161909
Empesertib (BAY1161909, Mps1-IN-5), a derivative of triazolopyridine, is an orally bioavailable, selective inhibitor of the serine/threonine monopolar spindle 1 (Mps1) kinase with IC50 of <1 nM. Empesertib has potential antineoplastic activity.
GC34068 McMMAF (Maleimidocaproyl monomethylauristatin F)
Maleimidocaproyl monomethylauristatin F
McMMAF (Maleimidocaproyl monomethylauristatin F) 是一种保护基团缀合的 MMAF。 MMAF 是一种有效的微管蛋白聚合抑制剂。
GC34022 Ombrabulin hydrochloride (AVE8062)
AVE8062 hydrochloride; AC7700 hydrochloride
A tubulin polymerization inhibitor and tumor vascular disrupting agent
GC33901 Pentanoic acid Pentanoicacid是一种短链脂肪酸，是细菌代谢产物，与过敏性皮肤病有关系。Pentanoicacid能够激活ROCK信号通路。
GC33421 PAK-IN-1 A group 2 PAK inhibitor
GC33420 BAY-1895344
BAY 1895344
An ATR inhibitor