Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC41110 16-epi Latrunculin B
16拉春库林B
An actin depolymerizing macrolide
GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone
2,3-二甲氧基-5-甲基-1,4-苯醌,CoQ0
An intermediate in the synthesis of ubiquinones that has anticancer activity
GC40901 Isogarcinol
Cambogin
A natural benzophenone that has immunosuppressant actions
GC40890 CAY10701 CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively).
GC40844 9-(2,2-Dicyanovinyl)julolidine
9-(2,2-二氰乙烯基)久洛啶,9-(2,2-Dicyanovinyl)julolidine
A fluorogenic dye
GC40802 (±)12(13)-DiHOME
Isoleukotoxin diol
A diol form of (±)12,13-EpOME
GC40795 CAY10503 A proapoptotic, antiproliferative compound
GC40793 L-erythro Sphinganine (d18:0)
L-苏式-二氢鞘胺醇
A bioactive sphingolipid
GC40758 Gly-Phe-β-naphthylamide
(S)-2-(2-氨基乙酰氨基)-N-(萘-2-基)-3-苯基丙酰胺
A cathepsin C substrate
GC40709 C2 L-threo Ceramide (d18:1/2:0)
L-threo Cer(d18:1/2:0), L-threo Ceramide (d18:1/2:0), N-acetyl-L-threo-Sphingosine
A bioactive sphingolipid
GC40708 C2 L-erythro Ceramide (d18:1/2:0)
L-erythro Cer(d18:1/2:0), L-erythro Ceramide (d18:1/2:0), N-acetyl-L-erythro-Sphingosine
A bioactive sphingolipid
GC40702 α-D-Galactopyranosylphenyl isothiocyanate
Α-D-吡喃半乳糖基苯基异硫氰酸酯
Used in neoglycoprotein preparation
GC40675 2-deoxy-Artemisinin
脱氧青蒿素
An inactive metabolite of artemisinin
GC40667 Aurora Kinase Inhibitor II
4-(4-Benzamidoanilino)-6,7-dimethoxyquinazoline
Blocks Aurora A kinase activity
GC40664 Colcemid
秋水仙碱,Demecolcine
Colcemid是一种细胞骨架抑制剂，可以在哺乳动物细胞或卵母细胞中诱导G2/M期的有丝分裂停滞或囊泡破裂（GVBD）期的减数分裂停滞。
GC40663 Corynecin V
棒状杆菌素V
A chloramphenicol-like bacterial metabolite
GC40624 MMP-3 Inhibitor VIII
Matrix Metalloproteinase-3 Inhibitor VIII, Stromelysin-1 Inhibitor VIII
A selective inhibitor of MMP-3
GC40622 Penicillide
Vermixocin A
A fungal metabolite with diverse biological activities
GC40618 3',4',7-Trihydroxyisoflavone
3',4',7-三羟基异黄酮
A natural isoflavone
GC40556 Ac-LETD-AFC
NAcetylLeuGluThrAsp7amino4Trifluoromethylcoumarin, Caspase8 Substrate (Fluorogenic)
A caspase-8 fluorogenic substrate
GC40482 Curvulin
2-乙酰基-3,5-二羟基苯乙酸乙酯
An inhibitor of microtubule assembly
GC40476 Allethrin
丙烯菊酯
A pyrethroid insecticide
GC40448 12(S)-HETE
12(S)-Hydroxyeicosatetraenoic Acid
The predominant lipoxygenase product of mammalian platelets
GC40296 D-erythro-MAPP
D-e-MAPP
An inhibitor of alkaline ceramidase
GC40265 Pheleuin A pyrazinone
GC34692 NU6140 A Cdk2 inhibitor
GC40256 p-APMSF (hydrochloride)
(4-脒苯基)甲磺酰氟盐酸盐
An irreversible inhibitor of serine proteases
GC40202 7α-hydroxy Cholesterol-d7
7ALPHA-羟基胆固醇-25,26,26,26-27,27,27-D7,7α-hydroxycholesterol-d7
An internal standard for the quantification of 7α-hydroxy cholesterol
GC40164 Ac-IETD-CHO (trifluoroacetate salt)
Caspase-8 Inhibitor
A caspase-8 inhibitor
GC40162 Ac-VEID-pNA (trifluoroacetate salt)
Ac-Val-Glu-Ile-Asp-pNA, Ac-Val-Glu-Ile-Asp-p-nitroanilide, Caspase-6 Chromogenic Substrate
A colorimetric caspase-6 substrate
GC40155 Biotin-DEVD-CHO (trifluoroacetate salt)
Biotin-Asp-Glu-Val-Asp-CHO
A biotinylated caspase-3 and -7 inhibitor
GC40154 Ac-ESMD-CHO (trifluoroacetate salt)
Ac-Glu-Ser-Met-Asp-CHO
An inhibitor of caspase-3 maturation
GC40153 Z-YVAD-AFC (trifluoroacetate salt)
Z-Tyr-Val-Ala-Asp-AFC, Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin, Z-YVAD-7-amino-4-trifluoromethylcoumarin
A fluorogenic substrate for caspase-1
GC40152 Ac-IEPD-pNA (trifluoroacetate salt)
Ac-Ile-Glu-Pro-Asp-p-nitroanilide, Caspase-8 Chromogenic Substrate, Granzyme B Substrate VIII
A colorimetric granzyme B and caspase-8 substrate
GC40151 Z-VAD-AMC (acetate)
Z-Val-Ala-Asp-AMC, Z-Val-Ala-Asp-7-amino-4-methylcoumarin
A caspase-1 fluorogenic substrate
GC40150 Z-VEID-AFC (trifluoroacetate salt)
Z-Val-Glu-Ile-Asp-AFC, Z-Val-Glu-Ile-Asp-7-amino-4-trifluormethylcoumarin
A fluorogenic substrate for caspase-6
GC40149 Boc-AEVD-CHO (trifluoroacetate salt)
Boc-Ala-Glu-Val-Asp-CHO
An inhibitor of caspase-8
GC40145 (S)-Laudanosine
(+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045
The (S) enantiomer of laudanosine
GC40125 Z-VA-DL-D(OMe)-FMK (trifluoroacetate salt)
Caspase-1 Inhibitor V, Z-VAD-FMK, Z-VAD(OMe)-FMK, Z-Val-Ala-DL-Asp(OMe)-Fluoromethyl Ketone
A pan-caspase inhibitor
GC40124 Ac-WEAD-AMC (trifluoroacetate salt)
Ac-Trp-Glu-Ala-Asp-AMC
A caspase-1 and caspase-4 fluorogenic substrate
GC40123 Ac-AAVALLPAVLLALLAP-VAD-CHO (trifluoroacetate salt)
Caspase Inhibitor II, Ac-AAVALLPAVLLALLAP-VAD-aldehyde, Ac-AAVALLPAVLLALLAPVAD-CHO
A non-selective caspase inhibitor
GC40122 Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt)
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO, Ac-AAVALLPAVLLALLAP-DEVD-aldehyde, Ac-AAVALLPAVLLALLAPDEVD-CHO, Caspase-3 Inhibitor I, DEVD-CHO-CPP 32
A caspase-3 inhibitor
GC40121 (Z-DEVD)2-Rh 110 (trifluoroacetate salt)
(Z-Asp-Glu-Val-Asp)2-Rhodamine 110
A fluorogenic substrate for caspase-3
GC40120 Mca-LEVDGW-K(Dnp)-NH2 (trifluoroacetate salt)
Mca-Leu-Glu-Val-Asp-Gly-Trp-Lys(Dnp)-NH2
A fluorogenic substrate for caspase-4
GC40119 Z-YVADLD-FMK (trifluoroacetate salt)
Z-Tyr-Val-Ala-Asp-Leu-Asp-FMK
A peptide
GC40118 Ac-AAVALLPAVLLALLAP-IETD-CHO (trifluoroacetate salt)
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO, Caspase-8 Inhibitor I
An inhibitor of caspase-8 and granzyme B
GC40094 all-trans Retinoic Acid-d5
atRA-d5, RA-d5, Vitamin A Acid-d5
An internal standard for the quantification of all-trans retinoic acid
GC40085 Pazopanib-d6
培唑帕尼-d6,GW786034-d6
An internal standard for the quantification of pazopanib
GC40060 Blasticidin A
灰瘟素A,(+)-Blasticidin A
A bacterial metabolite
GC40048 MPS1/TTK Inhibitor An inhibitor of Mps1/TTK