Cell Cycle/Checkpoint(细胞周期/检查点)

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more

Products for Cell Cycle/Checkpoint

Cat.No. 产品名称 Information
GC49682 Dabigatran-d3
BIBR 953-d3; BIBR 953ZW-d3
An internal standard for the quantification of dabigatran
GC49674 Schizandrin
五味子醇甲; Schizandrin; Schizandrol; Schizandrol-A
A lignan with diverse biological activities
GC49605 H-Gly-Pro-Hyp-OH (acetate)
H-GP-Hyp-OH, Tripeptide-29
A peptide DPP-4 inhibitor
GC49547 L-Glutamic Acid γ-p-Nitroanilide (hydrate)
γ-Glu-pNA, Glutamate γ-(4-Nitroanilide), L-GPNA, E-pNA
A colorimetric substrate for γ-glutamyl transpeptidase
GC49532 S-(1,2-Dichlorovinyl)-Cysteine (hydrochloride)
S-(1,2-dichlorovinyl)-L-Cysteine, S-(trans-1,2-dichlorovinyl)-L-Cysteine, DCVC
A nephrotoxin and metabolite of trichloroethylene
GC49491 N′-Nitrosonornicotine-d4
氘代N-亚硝基降烟碱(NNN)
An internal standard for the quantification of N'-nitrosonornicotine
GC49482 (±)-Nornicotine-d4
氘代降烟碱
An internal standard for the quantification of (±)-nornicotine
GC49471 LAMP1 Monoclonal Antibody (Clone Ly1C6) For immunochemical analysis of LAMP1
GC49469 IPG-1 TMA
APG-1, Asante Potassium Green-1, ION Potassium Green-1
A cell-impermeable fluorescent potassium indicator
GC49468 IPG-1 AM
APG-1 AM, Asante Potassium Green–1 AM, ION Potassium Green–1 AM, IPG-1 Acetoxymethyl ester
A cell-permeable fluorescent potassium indicator
GC49466 IPG-2 TMA
APG-2, Asante Potassium Green–2, ION Potassium Green–2, IPG-2
A cell-impermeable fluorescent potassium indicator
GC49463 IPG-2 AM
APG-2 Acetoxymethyl ester, APG-2 AM, Asante Potassium Green-2 Acetoxymethyl ester, Asante Potassium Green-2 AM, ION Potassium Green-2 Acetoxymethyl ester, ION Potassium Green-2 AM, IPG-2 Acetoxymethyl ester
A cell-permeable fluorescent potassium indicator
GC49460 ING-2 AM
ANG-2 Acetoxymethyl ester, ANG-2 AM, Asante Natrium Green-2 Acetoxymethyl ester, Asante Natrium Green-2 AM, ING-2 Acetoxymethyl ester, ION Natrium Green-2 Acetoxymethyl ester, ION Natrium Green-2 AM
A cell-permeable fluorescent sodium indicator
GC19897 Albendazole Sulfone
阿苯达唑砜
An active metabolite of albendazole
GC63774 MMAF-d8 hydrochloride D8-MMAF hydrochloride是MMAF hydrochloride的氘代形式。
GC63740 PF-06380101-d8
Aur0101-d8; Auristatin-0101-d8
PF-06380101 D8 (Aur0101 D8) 是 PF-06380101 的氘代物。PF-06380101 是一种 Auristatin 微管抑制剂，是一种细胞毒性 Dolastatin 10 类似物。
GC63716 Sovesudil hydrochloride
PHP-201 hydrochloride; AMA0076 hydrochloride
Sovesudil (PHP-201) hydrochloride 是一种有效的、ATP 竞争性局部作用 Rho 激酶 (ROCK) 抑制剂，对 ROCK I 和 ROCK II 的 IC50 分别为 3.7和2.3 nM。Sovesudil hydrochloride 可降低眼压而不引起充血。
GC63663 Avanbulin
BAL27862
Avanbulin (BAL27862) 是一种有效的秋水仙碱位点结合的微管蛋白 (tubulin) 装配抑制剂。Avanbulin 在 37 °C 抑制微管蛋白组装 (IC50=1.4 μM)。Avanbulin 与微管蛋白结合的 Kd 值为 244 nM。Avanbulin 可用于癌症和细胞分裂的研究。
GC63596 Fmoc-MMAE Fmoc-MMAE 是保护基团共轭连接到 MMAE。Mc-MMAE 是有效的微管蛋白抑制剂，可用于偶联抗体。
GC63576 10074-A4 10074-A4 是一种 c-Myc 结合化合物，与 c-Myc370–409 结合，表现得像“蛋白质云”周围的“配体云”，具有与非结合配体截然不同的特征。具有抗癌作用
GC63461 MMAE-d8
Monomethyl auristatin E-d8; Deuterated labeled MMAE
MMAE-d8是一种氘化标记的一甲基澳瑞他汀E（MMAE），可用于MMAE的检测。
GC63351 Sovesudil
PHP-201; AMA0076
Sovesudil (PHP-201) 是一种有效的、ATP 竞争性局部作用 Rho激酶 (ROCK) 抑制剂，对 ROCK I 和 ROCK II 的 IC50 分别为 3.7 和 2.3 nM。Sovesudil 降低眼压而不引起充血。
GC63333 Cotosudil Cotosudil 是一种 ROCK 激酶抑制剂，可用于青光眼或高眼压症的研究。
GC49443 7α-hydroxy Cholesterol
胆甾-5-烯-3,7二醇
An oxysterol and bile acid precursor
GC63253 Verosudil
AR-12286
Verosudil (AR-12286) 是一种有效的 Rho 激酶 (ROCK) 抑制剂，对 ROCK1 和 ROCK2 的 Ki 分别为 2 和 2 nM。AR-12286 主要通过增加眼房水通过小梁网流出来降低眼压。
GC63211 Tau tracer 2
Pl-2620
Tau tracer 2 (Pl-2620) 是一种 Tau 示踪剂，用于 Tau 蛋白聚集体成像。Tau tracer 2 可用于诊断神经退行性疾病。
GC63165 RAD51-IN-1 RAD51-IN-1 是 B02 的衍生物，是 RAD51 的有效抑制剂。 RAD51-IN-1 可用于癌症研究。
GC62777 2-Methoxy-4-vinylphenol
4-乙烯基-2-甲氧基苯酚
2-Methoxy-4-vinylphenol (2M4VP) 是天然的发芽抑制剂，具有抗炎活性。
GC62728 (1E)-CFI-400437 dihydrochloride CFI-400437 is a potent and selective polo-like kinase 4 (PLK4) inhibitor.
GC19849 SGC3027 A prodrug form of SGC8158
GC49437 Gliotoxin-13C13
Aspergillin-13C13
An internal standard for the quantification of gliotoxin
GC49430 Wee1 Inhibitor An inhibitor of Wee1
GC49419 Aniline-d5
苯胺-2,3,4,5,6-d5
An internal standard for the quantification of aniline
GC49412 NSC 756093 An inhibitor of the GBP1-Pim-1 protein-protein interaction
GC49404 Paclitaxel C
紫杉醇C
A taxoid and an inhibitor of microtubule depolymerization
GC49394 N-Nitroso Fluoxetine
氟西汀杂质22
A derivative of fluoxetine
GC49393 all-trans-13,14-Dihydroretinol A metabolite of all-trans retinoic acid
GC49390 13C6-4-Nitroaniline
13C6-p-Nitroaniline
An internal standard for the quantification of 4-nitroaniline
GC49387 Berberine-d6 (chloride)
Natural Yellow 18-d6 chloride
An internal standard for the quantification of berberine
GC49362 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline
2-氨基-3,8-二甲基咪唑并喹喔啉
A food-derived carcinogen
GC49353 N-Nitroso Metoprolol A genotoxic derivative of metoprolol
GC49351 N-Nitroso Atenolol
NO-Atenolol
A genotoxic derivative of (±)-atenolol
GC49345 Coelenterazine hcp
腔肠素HCP
A synthetic bioluminescent luciferin
GC49344 Fisetin-d5 An internal standard for the quantification of fisetin
GC49334 Chroman 1 (hydrochloride hydrate)
(S)-Chroman 1
A ROCK2 inhibitor
GC49322 GGACK (hydrochloride)
Glu-Gly-Arg-Chloromethyl Ketone, Glu-Gly-Arg-CH2Cl
A uPA and factor Xa inhibitor
GC49305 H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)
H-RGDC-OH
An RGD-containing tetrapeptide
GC49293 Dichlorvos-d6
敌敌畏
An internal standard for the quantification of dichlorvos
GC49280 GSK579289A A Plk1 inhibitor
GC49244 4-oxo Isotretinoin
4-酮13-顺式维甲酸
An active metabolite of isotretinoin