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Home >> Signaling Pathways >> Cell Cycle/Checkpoint >> Microtubule/Tubulin

Microtubule/Tubulin(微管/微管蛋白)

Microtubule is the cylindrical and filamentous structure that required for cell shape, migration, cilia and flagella mobility etc. Tubulin is the major component of microtubules.

Products for  Microtubule/Tubulin

  1. Cat.No. 产品名称 Information
  2. GC11905 Cevipabulin

    5-氯-6-[2,6-二氟-4-[3-(甲基氨基)丙氧基]苯基]-N-((1S)-2,2,2-三氟-1-甲基乙基)-[1,2,4]三唑并[1,5-A]嘧啶-7-胺,TTI-237

     An activator of microtubule polymerization
  3. GC16827 ELR510444 An inhibitor of tubulin polymerization
  4. GC17559 TAI-1 TAI-1 是一种口服活性抗癌剂，是一种高效的一流 Hec1 抑制剂，在 K562 细胞中的 GI50 为 13.48 nM。
  5. GC15285 MPC 6827 hydrochloride

    N-(4-甲氧基苯基)-N,2-二甲基-4-喹唑啉胺盐酸盐,MPC-6827 hydrochloride

     An inhibitor of tubulin polymerization with anticancer activity
  6. GC10334 INH6

    N-[4-(2,4,6-三甲基苯基)-2-噻唑基]苯甲酰胺

     A Hec1/Nek2 inhibitor
  7. GC17631 Combretastatin A4

    康普瑞汀; CRC 87-09

     A potent inhibitor of tubulin polymerization
  8. GC16727 Flutax 1 荧光紫杉醇衍生物；微管染色
  9. GC13484 Griseofulvin

    灰黄霉素

     A fungal metabolite with antifungal and anticancer activities
  10. GC14354 Eribulin

    艾日布林; B1939; E7389; ER-086526

     Eribulin (E7389) 是一种微管靶向剂，用于研究转移性乳腺癌。艾日布林通过结合微管蛋白和微管来抑制癌细胞的增殖。
  11. GC12483 Eribulin mesylate

    甲磺酸艾日布林; B1939 mesylate; E7389 mesylate; ER-086526 mesylate

     Eribulin mesylate (E7389 mesylate) 是一种微管靶向剂，用于研究转移性乳腺癌。甲磺酸艾日布林通过结合微管蛋白和微管来抑制癌细胞的增殖。
  12. GC13210 Flubendazole

    氟苯咪唑

     An anthelmintic
  13. GC13815 Vinflunine Tartrate

    长春氟宁酒石酸盐

    Etanercept is an inhibitor of the inflammatory factor TNF-α and is mainly used for the clinical treatment of rheumatoid arthritis .
  14. GC10537 Triclabendazole

    三氯苯达唑; CGA89317

     A benzimidazole anthelmintic
  15. GC11383 CYT997 (Lexibulin)

    CYT-997

     An inhibitor of microtubule polymerization
  16. GC12308 Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium

    CA 4DP; CA 4P; Combretastatin A4 disodium phosphate

     A potent inhibitor of tubulin polymerization
  17. GC16273 Dolastatin 10

    DLS 10; NSC 376128

     Dolastatin 10 (DLS 10) 是一种有效的抗有丝分裂肽，可抑制微管蛋白聚合。
  18. GC11765 Cabazitaxel

    卡巴他赛,XRP6258; RPR-116258A; taxoid XRP6258

     A semisynthetic taxane
  19. GC10235 Plinabulin (NPI-2358)

    普那布林; NPI-2358

     A tubulin depolymerizing agent
  20. GC14288 KX2-391

    5-[4-[2-(4-吗啉基)乙氧基]苯基]-N-(苯基甲基)-2-吡啶乙酰胺,KX2-391; KX-01

     A Src kinase inhibitor
  21. GC10034 MMAF

    一甲基澳瑞他汀F,Monomethylauristatin F

     An auristatin with anticancer activity
  22. GC11252 CW069 An inhibitor of KIFC/HSET
  23. GC15894 CK-636

    CK-0944636

     An inhibitor of Arp2/3 complex action
  24. GC14075 Nocodazole

    诺考达唑

     Nocodazole是一种抗有丝分裂药物，是一种快速可逆的微管聚合抑制剂，在无细胞试验中抑制Abl，Abl（E255K）和Abl（T315I），IC50值分别为0.21μM，0.53μM和0.64μM。
  25. GC11202 Epothilone A

    埃博霉素A,Epo A

     An antimicrotubule agent
  26. GC17240 Epothilone B (EPO906, Patupilone)

    埃博霉素B; EPO 906; Patupilone

     Microtubule stabilizing agent
  27. GC15875 ABT-751 (E7010)

    N-[2-[(4-羟基苯基)氨基]-3-吡啶基]-4-甲氧基苯磺酰胺,E7010

     An inhibitor of microtubule polymerization
  28. GC11511 Vincristine sulfate

    硫酸长春新碱; Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate

    An antimitotic inhibitor of tubulin polymerization
  29. GC14806 Vinorelbine ditartrate

    酒石酸长春瑞滨; KW-2307; Nor-5'-anhydrovinblastine ditartrate

     An inhibitor of microtubule polymerization
  30. GC12286 Vinblastine sulfate

    硫酸长春碱; Vincaleukoblastine sulfate salt

     An inhibitor of microtubule assembly
  31. GC10521 Podophyllotoxin

    鬼臼毒素; Podophyllotoxin

     A lignan with diverse biological activities
  32. GC17276 Monomethyl auristatin E

    一甲基澳瑞他汀E,Vedotin; MMAE

     Monomethyl Auristatin E (MMAE)，作为海兔毒素 10 的合成衍生物，海兔毒素 10 是一种线性五肽，最初是从海兔 Dolabella auriculari 的提取物中分离出来的。
  33. GC15798 MMAD

    单甲基澳瑞他汀D,Demethyldolastatin 10;Monomethylauristatin D;Monomethyl Dolastatin 10

     MMAD 是一种有效的微管蛋白抑制剂，是抗体药物偶联物 (ADC) 中的一种毒素有效载荷。
  34. GC10222 KX2-391 dihydrochloride

    5-[4-[2-(4-吗啉基)乙氧基]苯基]-N-(苯基甲基)-2-吡啶乙酰胺盐酸盐,KX2-391 2HCl; KX2-391

     A Src kinase inhibitor
  35. GC16869 Ixabepilone

    伊沙匹隆; BMS-247550; Aza-epothilone B

     A broad-spectrum anticancer agent
  36. GC17440 Epothilone D

    埃博霉素; KOS 862

     A microtubule-stabilizing agent
  37. GC12550 Docetaxel Trihydrate

    三水多烯紫杉醇,Taxotere Trihydrate

     Docetaxel Trihydrate (RP-56976 Trihydrate) 是一种抗肿瘤剂，可抑制微管解聚，IC50 值为 0.2 μM。 Docetaxel Trihydrate 是紫杉醇的半合成类似物，可减弱 bcl-2 和 bcl-xL 基因表达的影响。 Docetaxel Trihydrate 在 G2/M 停止细胞周期并导致细胞凋亡。
  38. GC12384 D-64131

    D 64131;D64131

     An inhibitor of tubulin polymerization
  39. GC13261 Colchicine

    秋水仙碱

     Colchicine（秋水仙碱）是一种可口服的生物碱，通过抑制β-微管蛋白聚合成微管来破坏细胞骨架功能，Colchicine抑制微管的IC50为3 nM。
  40. GC11947 Ansamitocin P-3

    安丝菌素P 3; Antibiotic C 15003P3; Maytansinol isobutyrate

     A microtubule depolymerizing agent
  41. GC17271 4'-Demethylepipodophyllotoxin

    4'-去甲基表鬼臼毒素; 4'-O-demethylepipodophyllotoxin; 4'-DMEP

     An inhibitor of tubulin polymerization
  42. GC12954 10-DAB (10-Deacetylbaccatin)

    10-脱乙酰巴卡丁 III

     An inhibitor of microtubule assembly
  43. GC16684 Docetaxel

    多西他赛; RP-56976

     Docetaxel是紫杉烷类抗有丝分裂化疗药物,IC50为0.2 µM。
  44. GC12511 Paclitaxel (Taxol)

    紫杉醇

     紫杉醇是从短叶红豆杉的树皮和针叶中提取出来的三环二萜化合物。
  45. GC15084 2-Methoxyestradiol (2-MeOE2)

    二甲氧基雌二醇; 2-ME2; NSC-659853

     2-Methoxyestradiol (2-MeOE2/2-Me)是一种HIF-1α抑制剂。
  46. GN10426 Deacetyltaxol

    10-去乙酰紫杉醇; 10-Deacetylpaclitaxel

     An anticancer taxane
  47. GN10780 Cephalomannine

    三尖杉宁碱

     A taxane diterpenoid
  48. GN10625 7-Epitaxol

    7-表紫杉醇; 7-epi-Paclitaxel

     An active metabolite of paclitaxel
  49. GN10299 Vinorelbine

    长春瑞宾

     An inhibitor of microtubule polymerization

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