DNA Damage/DNA Repair(DNA损伤/DNA修复)
- MTH1(4)
- PARP(106)
- ATM/ATR(28)
- DNA Alkylating(22)
- DNA Ligases(3)
- DNA Methyltransferase(29)
- DNA-PK(28)
- HDAC(151)
- Nucleoside Antimetabolite/Analogue(145)
- Telomerase(13)
- Topoisomerase(142)
- tankyrase(5)
- Antifolate(32)
- CDK(235)
- Checkpoint Kinase (Chk)(28)
- CRISPR/Cas9(9)
- Deubiquitinase(64)
- DNA Alkylator/Crosslinker(71)
- DNA/RNA Synthesis(441)
- Eukaryotic Initiation Factor (eIF)(22)
- IRE1(22)
- LIM Kinase (LIMK)(11)
- TOPK(6)
- Casein Kinase(42)
- DNA Intercalating Agents(8)
- DNA/RNA Oxidative Damage(13)
- Cat.No. 产品名称 Information
- GC48664 Enoxacin-d8 (hydrochloride) An internal standard for the quantification of enoxacin
-
GC48662
5'-Thymidylic Acid (sodium salt)
胸苷酸二钠
A deoxyribonucleotide -
GC48635
(-)-Cryptopleurine
(R)-Cryptopleurine, NSC 19912
An alkaloid with diverse biological activities -
GC48533
Vanoxonin
Antibiotic MG 245CF2A
A bacterial metabolite -
GC48457
3-keto Fusidic Acid
3-酮基夫西地酸(欧洲药典标准品)
An active metabolite of fusidic acid - GC48445 Hygromycin B (hydrate) An aminoglycoside antibiotic
-
GC48440
2'-Deoxycytidine-5'-triphosphate (sodium salt)
2'-脱氧胞苷-5'-三磷酸三钠盐,dCTP trisodium salt; 2′-Deoxycytidine-5′-triphosphate trisodium salt
A nucleoside triphosphate -
GC48388
Heliquinomycin
NSC 702208, Rubymycin
A bacterial metabolite with diverse biological activities -
GC48372
Erythromycin 2'-Propionate
红霉素丙酸酯
An antibiotic - GC48365 Bottromycin A2 An antibiotic
- GC50719 FMF-04-159-R Potent inhibitor of CDK16 and CDK14 (IC50 values are 6 and 140 nM, respectively in kinase activity assay; IC50 = 563 nM for CDK14 in BRET assay)
- GC50656 BAY 707 BAY 707 是一种底物竞争性、高效和选择性的 MTH1(NUDT1) 抑制剂,IC50 为 2.3 nM。 BAY 707 与其他 MTH1 化合物相比具有良好的药代动力学 (PK) 特征,并且在小鼠中具有良好的耐受性,但明显缺乏体外或体内抗癌功效。
-
GC19566
N-Nitrosodiethylamine (950mg/mL)
N-亚硝基二乙胺 ;N-二乙基亚硝胺
N-Nitrosodiethylamine (Diethylnitrosamine) 是一种有效的肝癌致癌二烷基亚硝胺。 N-亚硝基二乙胺主要存在于烟草烟雾、水、切达奶酪、腌制食品、油炸食品和许多酒精饮料中。 N-亚硝基二乙胺负责与 DNA 修复/复制相关的核酶的变化。 N-亚硝基二乙胺在所有动物物种中导致各种肿瘤。主要靶器官为鼻腔、气管、肺、食道和肝脏。
- GC48190 TP-4748 A heterocyclic building block
-
GC48165
Thiocoraline
PM 93135
A depsipeptide and DNA bis-intercalator with antibacterial and anticancer activities -
GC48141
Temozolomide-d3
替莫唑胺 d3
An internal standard for the quantification of temozolomide -
GC48120
T-2 Toxin-13C24
Fusariotoxin T-2-13C24, Insariotoxin-13C24, Mycotoxin T-2-13C24
A neuropeptide with diverse biological activities -
GC48118
Sunitinib-d10
舒尼替尼-D10,SU 11248-d10
An internal standard for the quantification of sunitinib - GC47933 Pemetrexed-13C5 (sodium salt hydrate) A neuropeptide with diverse biological activities
- GC47817 Olaparib-d4 A neuropeptide with diverse biological activities
-
GC47693
m-Methoxybenzamide
3-甲氧基苯甲酰胺,3-MBA
A PARP inhibitor -
GC47552
Leflunomide-d4
来氟米特 d4
An internal standard for the quantification of leflunomide - GC47521 K22 An antiviral agent
-
GC47276
D-threo-PPMP (hydrochloride)
D-threo-1-phenyl-2-Palmitoylamino-3-morpholino-1-propanol
A GlyCer synthetase inhibitor -
GC47167
Dacarbazine-d6
达卡巴嗪-D6,Imidazole Carboxamide-d6
An internal standard for the quantification of dacarbazine -
GC47162
Cytidine 5'-triphosphate (sodium salt hydrate)
胞嘧啶核苷5`-三磷酸二钠盐水合物
A pyrimidine nucleoside triphosphate -
GC47148
Cyclophosphamide-d4
环磷酰胺 d4
An internal standard for the quantification of cyclophosphamide - GC47098 CL2-SN-38 (dichloroacetic acid salt) An antibody-drug conjugate containing SN-38
-
GC47078
Chlorambucil-d8
CB-1348-d8; WR-139013-d8
苯丁酸氮芥 (CB-1348-d8) 是氘标记的苯丁酸氮芥。苯丁酸氮芥 (CB-1348) 是一种具有口服活性的抗肿瘤剂,是一种属于氮芥类的双功能烷化剂。苯丁酸氮芥可用于淋巴细胞白血病、卵巢癌和乳腺癌以及霍奇金病的研究。 - GC47059 CAY10760 An inhibitor of the RAD51-BRCA2 interaction
- GC47056 CAY10753 A TNKS2 inhibitor
- GC47055 CAY10749 A dual inhibitor of PARP and PI3K
-
GC46962
Busulfan-d8
白消安 d8
An internal standard for the quantification of busulfan -
GC46914
Bendamustine-d4 (hydrochloride)
盐酸苯达莫司汀 d4 (盐酸盐)
A neuropeptide with diverse biological activities - GC46900 AZ9482 A PARP inhibitor
-
GC46895
Aurintricarboxylic Acid (ammonium salt)
铝试剂
A protein synthesis inhibitor with diverse biological activities - GC46880 ARN24139 A topoisomerase II poison
-
GC46814
Aflatoxin M1-13C17
AFM1-13C17
A neuropeptide with diverse biological activities -
GC46810
Aflatoxin B1-13C17
黄曲霉毒素B1-(全碳-13)
An internal standard for the quantification of aflatoxin B1 -
GC46806
Adenosine 5'-diphosphate (potassium salt hydrate)
5'-ADP, ADP
A neuropeptide with diverse biological activities -
GC46744
8-Bromoadenosine 5′-triphosphate (sodium salt hydrate)
8-bromo ATP
A neuropeptide with diverse biological activities -
GC46733
7,12-Dimethylbenz[a]anthracene
9,10-二甲基-1,2-苯并蒽;DMBA
7,12-Dimethylbenz[a]anthracene是一种免疫抑制剂,也是一种强效的器官特异性致癌物。 -
GC46713
5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)
Phosphoribosyl Pyrophosphate, P-rib-PP, PRPP
An intermediate in several biochemical pathways -
GC46681
5-Bromouridine
5-溴尿苷
A brominated uridine analog -
GC46607
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
4-甲基亚硝胺基-1-3-吡啶基-1-丁酮(NNK),NNK
A tobacco-specific nitrosamine carcinogen - GC46540 2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate) A purine nucleotide
-
GC46524
2,6-Dichloropurine-9-β-D-riboside
2,6-二氯嘌呤核苷
A building block -
GC46519
2',3'-O-Isopropylideneguanosine
2',3'-O-异丙亚基鸟苷
A building block -
GC46508
2',2'-Difluoro-2'-deoxyuridine
2'-脱氧-2',2'-二氟尿嘧啶核苷
An active metabolite of gemcitabine -
GC46474
18-Deoxyherboxidiene
RQN-18690A
A bacterial metabolite with antiangiogenic activity