DNA Damage/DNA Repair(DNA损伤/DNA修复)

Cat.No. 产品名称 Information

GC45057 TIQ-A A PARP1 inhibitor

GC45009 Temafloxacin

替马沙星,TMFX; TA-167 free acid; A-62254 free acid

A DNA topoisomerase inhibitor

GC44984 TAF 10 Peptide

TAF10 RNA Polymerase II, TATA Box Binding Protein (TBP)Associated Factor, TBPAssociated Factor 10, TAFII30

A peptide associated with RNA polymerase II activity

GC44983 T2AA (hydrochloride)

T2-amino Alcohol

An inhibitor of PCNA

GC44981 T-2 Toxin

T-2毒素(镰刀菌属),T-2 Mycotoxin

A trichothecene mycotoxin

GC44953 Sterigmatocystin

甾体半胱氨酸

甾体半胱氨酸是由曲霉属真菌产生的一种霉菌毒素。

GC44897 SL 01

N-苯氧基碳-L-苯丙氨酰甲基氯酮,SL-01

An inhibitor of SARS-CoV M^pro

GC44809 Rebeccamycin

蝴蝶霉素

A DNA topoisomerase I inhibitor

GC44685 Procaine (hydrochloride)

Novocaine

Procaine (hydrochloride) is an analytical reference standard categorized as a local anesthetic that is used as an adulterant.

GC44681 preQ1 (hydrochloride)

Pre-Queuosine 1

A precursor of queuosine

GC44651 Pixantrone (maleate)

马来酸匹衫琼; BBR 2778

A DNA topoisomerase II inhibitor

GC44612 PF-4800567 A selective CK1ε inhibitor

GC44591 Pemetrexed (sodium salt hydrate)

培美曲赛二钠七水合物,LY231514 disodium heptahydrate

An antifolate with anticancer activity

GC44438 Nogalamycin

诺拉霉素

An anthracycline with anticancer activity

GC44408 Nitrosobenzene

亚硝基苯

A spin trap

GC44348 N-desmethyl Bendamustine

盐酸苯达莫司汀乙酯水解杂质

An active metabolite of bendamustine

GC44251 MTIC

替莫唑胺代谢物- MTIC

A DNA alkylating agent

GC44243 Monohydroxy Melphalan (hydrochloride)

Hydroxymelphalan

A DNA alkylating agent

GC44200 Mitomycin A

丝裂霉素A

A bacterial metabolite

GC44094 LX7101 (hydrochloride) A LIMK and ROCK inhibitor

GC43798 Guanylyl Imidodiphosphate (lithium salt)

Gpp(NH)p lithium

Guanylyl Imidodiphosphate (lithium salt)是一种稳定的GTP类似物，是腺苷酸环化酶的有效激活剂。

GC43796 Guanosine 5′-triphosphate (sodium salt hydrate)

鸟苷-5'-三磷酸二钠盐三水合物

An energy substrate for protein synthesis and gluconeogenesis

GC43726 Gallotannin

单宁酸

单宁酸（Gallotannin；Tannic acid）是一种天然多酚化合物，已在各种植物中发现，具有抗氧化、抗炎、抗血管生成、抗病毒和抗肿瘤等生物活性。Gallotannin抑制DNA聚合酶α、β和κ的活性，IC₅₀值分别为13、130和30nM。

GC43618 Epiblastin A An inhibitor of CK1α, CK1δ, and CK1ε

GC43565 Doxorubicinol (hydrochloride)

13-Dihydroadriamycin hydrochloride

A doxorubicin metabolite

GC43351 Cylindrospermopsin

柱孢藻毒素

A cyanotoxin

GC43209 CB-1954

5-(1-氮杂环丙基)-2,4-二硝基苯甲酰胺,CB 1954

An antitumor prodrug

GC43175 CAY10574 A Cdk2-cyclin E and Cdk9 inhibitor

GC43111 C8 L-threo Ceramide (d18:1/8:0)

L-threo Cer(d18:1/8:0), L-threo Ceramide (d18:1/8:0), N-octanoyl-L-threo-Sphingosine

A bioactive sphingolipid

GC43109 C8 D-threo Ceramide (d18:1/8:0)

D-threo Cer(d18:1/8:0), D-threo Ceramide (d18:1/8:0), N-octanoyl-D-threo-Sphingosine

A bioactive sphingolipid

GC42978 Bromamphenicol A dibrominated derivative of chloramphenicol

GC42912 Becatecarin

NSC 655649; BMS 181176; BMY 27557

A water-soluble antineoplastic antibiotic

GC42789 Aminopterin

氨基蝶呤; 4-Aminofolic acid; APGA

A synthetic folic acid derivative

GC42783 Ametantrone

阿美蒽醌,NSC 196473; NSC 290813

An inhibitor of topoisomerase II

GC42765 Aldehyde Reactive Probe (trifluoroacetate salt)

ARP, O(Biotinylcarbazoylmethyl) Hydroxylamine

A biotinylated probe for detecting AP sites in damaged DNA

GC42734 Adenosine 5'-phosphosulfate (sodium salt) An ATP sulfurylase and APS Kinase inhibitor

GC42733 Adenosine 5'-monophosphate (sodium salt hydrate)

AMP钠盐

A central cellular nucleotide

GC42732 Adenosine 3',5'-diphosphate (sodium salt)

腺苷3`,5`-二磷酸钠盐

An adenine nucleotide containing two phosphate groups

GC42627 8-Hydroxyguanine (hydrochloride)

依达比星杂质2

Product of oxidative damage to DNA or RNA

GC42562 5-Methyl-2'-deoxycytidine

5-甲基-2'-脱氧胞苷,5-Methyldeoxycytidine

A pyrimidine nucleoside

GC42545 5-Fluorouracil-13C,15N2

5-FU-13C,15N2

An internal standard for the quantification of 5-fluorouracil

GC42474 4-Thiouridine

4-硫代尿苷

4-Thiouridine 4-硫脲(4sU)是核糖核苷类似物，可用于RNA分析和(m)RNA标记。

GC42464 4-oxo-2-Nonenal

4-ONE

A lipid peroxidation product

GC42401 4-hydroperoxy Cyclophosphamide

培磷酰胺,4-OOH-CY

4-hydroperoxy Cyclophosphamide（4-羟基过氧化环磷酰胺），环磷酰胺的活性代谢产物，能够交联DNA并独立于caspase受体激活诱导T细胞凋亡，通过产生活性氧（ROS）激活线粒体死亡途径。

GC42197 2-Thiouridine

2-硫代尿苷

A modified nucleobase

GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

dGMP

A natural precursor of dGTP

GC42080 2'2'-cGAMP (sodium salt)

Adenosine-Guanosine 2’,2’-cyclic monophosphate, cGAMP(2’-5’), 2’,2’-Cyclic GMP-AMP

A synthetic dinucleotide

GC42061 2',3'-Dideoxyadenosine 5'-triphosphate

2',3'-Dideoxyadenosine 5'-triphosphate

2',3'-Dideoxyadenosine 5'-triphosphate (2',3'-Dideoxyadenosine 5'-triphosphate), an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase.

GC41859 1,5,7-Triazabicyclo[4.4.0]dec-5-ene

157-三叠氮双环(4.4.0)癸-5-烯

A bicyclic guanidine catalyst

GC41716 (R)-CR8

(2R)-2-[[9-异丙基-6-[[[4-(2-吡啶基)苯基]甲基]氨基]-9H-嘌呤-2-基]氨基]-1-丁醇,CR8, (R)-Isomer

An inhibitor of cyclin-dependent kinases