DNA Damage/DNA Repair(DNA损伤/DNA修复)
- MTH1(4)
- PARP(106)
- ATM/ATR(28)
- DNA Alkylating(22)
- DNA Ligases(3)
- DNA Methyltransferase(29)
- DNA-PK(28)
- HDAC(151)
- Nucleoside Antimetabolite/Analogue(145)
- Telomerase(13)
- Topoisomerase(142)
- tankyrase(5)
- Antifolate(32)
- CDK(235)
- Checkpoint Kinase (Chk)(28)
- CRISPR/Cas9(9)
- Deubiquitinase(64)
- DNA Alkylator/Crosslinker(71)
- DNA/RNA Synthesis(441)
- Eukaryotic Initiation Factor (eIF)(22)
- IRE1(22)
- LIM Kinase (LIMK)(11)
- TOPK(6)
- Casein Kinase(42)
- DNA Intercalating Agents(8)
- DNA/RNA Oxidative Damage(13)
- Cat.No. 产品名称 Information
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GC18404
Lometrexol
洛美曲索,DDATHF
A GART inhibitor
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GC18402
GSK3117391
An HDAC inhibitor
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GC18396
PD 407824
An inhibitor of Chk1 and WEE1
-
GC18354
Bisindolylmaleimide X (hydrochloride)
BIM-X hydrochloride; Ro31-8425 hydrochloride
A PKC inhibitor
-
GC18303
MKC-3946
An inhibitor of IRE1α
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GC18206
WT161
A potent inhibitor of HDAC6
-
GC18186
L67
DNA Ligase Inhibitor
A DNA ligase inhibitor
-
GC18172
E7449
E7449; 2X-121
An inhibitor of PARP1, PARP2, and TNKS1/2
-
GC18160
USP7/USP47 inhibitor
4-氰基-5-[(3,5-二氯-4-吡啶基)硫基]-N-[4-(甲基磺酰基)苯基]-2-噻吩甲酰胺
A dual inhibitor of USP7 and USP47
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GC11302
Hinokitiol
桧木醇; β-Thujaplicin
A tropolone with diverse biological activities
-
GC15168
Urolithin A
尿石素A
A metabolite of ellagic acid with diverse biological activities
-
GC15294
DPQ
DMEM低糖
An inhibitor of poly(ADP-ribose) polymerases
-
GC12367
CM-272
An inhibitor of G9a, GLP, and DNA methyltransferases
-
GC12266
Didox
3,4-二羟基苯甲羟肟酸,NSC-324360
Antioxidant and ribonucleotide reductase inhibitor
-
GC11903
9-amino Camptothecin
9-氨基喜树碱; 9-amino-20(S)-camptothecin
A DNA topoisomerase I inhibitor
-
GC11949
MI-192
A selective HDAC2/3 Inhibitor
-
GC10779
Alternariol
交链孢酚
A mycotoxin
-
GC12638
UK 1
2'-(2-羟基苯基)-[2,4'-联苯并恶唑]-4-羧酸甲酯
A cytotoxic Streptomyces metabolite
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GC14335
SCR7 pyrazine
SCR7 吡嗪
SCR7 pyrazine 是一种 DNA 连接酶 IV 抑制剂，以连接酶 IV 依赖性方式阻断非同源末端连接 (NHEJ)。 SCR7 吡嗪也是一种 CRISPR/Cas9 增强剂，可提高 Cas9 介导的同源定向修复 (HDR) 的效率。 SCR7 pyrazine 可诱导细胞凋亡并具有抗癌活性。
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GC16949
Guanine
鸟嘌呤
A purine base
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GC14331
Folinic acid
亚叶酸; leucovorin
亚叶酸 (Leucovorin) 是一种生物叶酸，通常与甲氨蝶呤 (MTX) 一起作为救援剂给药，以降低 MTX 诱导的毒性。
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GC12634
Deoxyguanosine 5-triphosphate
2'-脱氧鸟苷-5'-三磷酸三钠盐,dGTP trisodium salt; 2'-Deoxyguanosine-5'-triphosphate trisodium salt
A nucleoside triphosphate
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GC15841
Alsterpaullone
阿特波龙,9-Nitropaullone,NSC 705701
A dual CDK and GSK3 inhibitor
-
GC13399
Trimidox
VF 233
A ribonucleotide reductase inhibitor
-
GC14016
Sulforaphane
萝卜硫素
萝卜硫素 (SFN) 称为 [1-isothiocyanato-4-(methylsulfinyl)butane]。
-
GC18100
Illudin S
隐陡头菌素S
A DNA alkylating agent
-
GC13510
3-AP
[(3-氨基吡啶-2-基)亚甲基氨基]硫脲,3-Aminopyridine-2-Carboxyaldehyde Thiosemicarbazone,NSC 663249,Triapine?
A ribonucleotide reductase inhibitor
-
GC10834
Isoxanthopterin
異黃喋呤,NSC 118090,NSC 614991
An intermediate in the pteridine pathway
-
GC14058
CBHA
Histone Deacetylase Inhibitor II,m-Carboxycinnamic Acid bis-Hydroxamide
Inhibitor of histone deacetylases
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GC15043
Trioxsalen
三甲沙林; Trisoralen; Trioxysalen; TMP
A UV-activated DNA crosslinking probe
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GC15612
Luotonin A
A cytotoxic alkaloid
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GC11761
4-amino-1,8-Naphthalimide
4-氨基-1,8-萘二胺,4-Aminonaphthalimide,4-ANI
A PARP inhibitor
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GC12334
HNHA
N-羟基-7-(2-萘硫基)-庚酰胺,Histone Deacetylase Inhibitor VI
HDAC inhibitor
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GC15336
Luotonin F
A plant alkaloid with anticancer activity
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GC13925
Nullscript
A negative control for scriptaid
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GC15815
Thymidine
胸苷; DThyd; NSC 21548
A pyrimidine nucleoside
-
GC16265
RS-1
4-溴-N-(4-溴苯基)-3-[[(苯基甲基)氨基]磺酰基]苯甲酰胺
A RAD51 activator
-
GC13978
JW 74
An inhibitor of TNKS1/2
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GC11022
SB 218078
A potent Chk1 inhibitor
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GC10867
(+)-Aphidicolin
阿非迪霉素
阿非迪霉素是真核DNA复制的可逆抑制剂，可阻断前S期的细胞周期。
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GC11593
AZD0156
An ATM kinase inhibitor
-
GC14808
Saccharin 1-methylimidazole (SMI)
糖精1-甲基咪唑
A chemical activator of DNA and RNA synthesis
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GC14597
ITSA-1 (ITSA1)
ITSA-1 是一种组蛋白去乙酰化酶（HDAC）激活剂，能够抑制HDAC抑制剂TSA对HDAC的抑制，但不抑制其他HDAC抑制剂。
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GC15607
ON123300
8-环戊基-7,8-二氢-2-[[4-(4-甲基-1-哌嗪基)苯基]氨基]-7-氧代-吡啶并[2,3-D]嘧啶-6-甲腈,ON123300
A multi-kinase inhibitor
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GC16485
RHPS4
A telomerase inhibitor
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GC16879
Tubercidin
结核菌素; 7-Deazaadenosine
Tubercidin 是一种吡咯并嘧啶核苷类似物，对血吸虫感染具有显着活性。
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GC16725
AZ6102
REL-2-[4-[6-[(3R,5S)-3,5-二甲基-1-哌嗪基]-4-甲基-3-吡啶基]苯基]-3,7-二氢-7-甲基-4H-吡咯并[2,3-D]嘧啶-4-酮
A TNKS1/2 inhibitor
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GC12844
Benzamide
苯甲酰胺; Benzenecarboxamide; Phenylamide
Benzamide (Benzenecarboxamide) 是一种有效的聚 (ADP-核糖) 聚合酶 (PARP) 抑制剂。
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GC14251
Picolinamide
2-吡啶甲酰胺,2-Picolinamide
poly (ADP-ribose) synthetase inhibitor
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GC14107
Oxolinic acid
恶喹酸
An inhibitor of bacterial DNA gyrase