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Home >> Signaling Pathways >> DNA Damage/DNA Repair

DNA Damage/DNA Repair(DNA损伤/DNA修复)

Cat.No. 产品名称 Information
GC19342 SW044248 A DNA topoisomerase I inhibitor
GC19337 SR-4370 An HDAC3 inhibitor
GC19336 SR-3029 An inhibitor of CK1δ and CK1ε
GC19328 SF2523 A dual inhibitor of PI3K and BRD4
GC19326 Senexin B
4-[[2-[6-[(4-甲基-1-哌嗪基)羰基]-2-萘基]乙基]氨基]-6-喹唑啉甲腈
An inhibitor of Cdk8 and Cdk19
GC19319 Sapacitabine
N-[1-[(2R,3S,4S,5R)-3-氰基-4-羟基-5-(羟甲基)氧杂环戊-2-基]-2-氧代嘧啶-4-基]十六酰胺,CS682; CYC682
Sapacitabine 是一种可口服的核苷类似物前药，在结构上与阿糖胞苷相关。
GC19309 RG7800
RO6885247
RG7800 是一种 SMN2 拼接修饰剂。
GC19267 NU2058
O6-(Cyclohexylmethyl)guanine
An inhibitor of Cdk1 and Cdk2
GC19264 NMS-P118
2-[1-(4,4-二氟环己基)-4-哌啶基]-6-氟-2,3-二氢-3-氧代-1H-异吲哚-4-甲酰胺
A potent and selective PARP1 inhibitor
GC19263 NKP-1339
IT-139; KP-1339
A ruthenium complex with anticancer activity
GC19238 Madrasin
DDD00107587
A cell-permeant inhibitor of pre-mRNA splicing
GC19233 LY3177833 An inhibitor of Cdc7 kinase
GC19227 LTURM34 An inhibitor of DNA-PK
GC19219 LDC4297 A CDK7 inhibitor
GC19212 KIRA6
IRE1 Inhibitor IV, IRE1α Kinase Inhibiting RNase Attenuator 6
An IRE1α RNase inhibitor
GC19190 HDAC-IN-4
CXD101
An HDAC inhibitor
GC19189 HDAC8-IN-1
MDK-7933
An HDAC8 inhibitor
GC19148 Exatecan Mesylate
依喜替康甲磺酸盐; DX8951f
A DNA topoisomerase I inhibitor
GC19129 EDO-S101
Tinostamustine
An HDAC inhibitor and DNA alkylating agent
GC19110 COH29
RNR Inhibitor COH29
COH29 (RNR Inhibitor COH29) 是一种有效的核糖核苷酸还原酶 (RNR) 抑制剂，具有抗癌活性。 COH29 抑制 RNR 的 α 和 β 亚基，IC50 为 16 μM。
GC19099 CeMMEC13 A selective TAF1 bromodomain 2 inhibitor
GC19098 CeMMEC1 A selective TAF1 bromodomain 2 inhibitor
GC19096 CDKI-73
LS-007
CDKI-73 (LS-007) 是一种具有口服活性且高效的 CDK9 抑制剂，对 CDK9、CDK1 和 CDK2 的 Ki 值分别为 4 nM、4 nM 和 3 nM。
GC19093 CCT245737 A potent Chk1 inhibitor
GC19089 CC-671 A dual inhibitor of Mps1/TTK and Clk2
GC19086 Calicheamicin
卡奇霉素; Calicheamicin γ1
加利车霉素是一种抗肿瘤抗生素，是一种导致双链 DNA 断裂的细胞毒剂。
GC19083 Briciclib
ON 014185
An eIF4E inhibitor
GC19076 BMS-3 An inhibitor of LIMK1 and LIMK2
GC19073 Bisantrene
比生群; CL216942
Bisantrene 是一种高效的抗肿瘤药物，靶向真核生物 II 型拓扑异构酶。
GC19067 BGG463
K03859
BGG463 (K03859) 是一种具有口服活性的 II 型 CDK2 抑制剂。
GC19047 AZ32 An ATM kinase inhibitor
GC19020 ACY-738
N-羟基-2-[(1-苯基环丙基)氨基]-5-嘧啶甲酰胺
An HDAC6 inhibitor
GC18853 4-isocyanato TEMPO A spin label for RNA
GC18840 Gilvocarcin V
褐黄癌菌素V
An antitumor antibiotic
GC18769 MST-312
Telomerase Inhibitor IX
A telomerase inhibitor
GC18751 Reticulol
网状菌醇
A cAMP phosphodiesterase and DNA topoisomerase I inhibitor
GC18734 JS-K A nitric oxide donor
GC18666 Debromohymenialdisine
DBH, SKF 108753
An inhibitor of Chk1 and Chk2
GC18640 cis-9,10-Methyleneoctadecanoic Acid methyl ester
顺9,10-甲基十九烷酸甲酯
A cyclopropane fatty acid methyl ester
GC18536 Chartreusin
教酒菌素
An antibiotic with diverse biological activites
GC18437 Alternariol monomethyl ether
交链孢霉甲基醚
A mycotoxin
GC18426 8-Nitroguanine A mutagenic nitrative guanine derivative
GC18404 Lometrexol
洛美曲索,DDATHF
A GART inhibitor
GC18402 GSK3117391 An HDAC inhibitor
GC18396 PD 407824 An inhibitor of Chk1 and WEE1
GC18354 Bisindolylmaleimide X (hydrochloride)
BIM-X hydrochloride; Ro31-8425 hydrochloride
A PKC inhibitor
GC18303 MKC-3946 An inhibitor of IRE1α
GC18206 WT161 A potent inhibitor of HDAC6
GC18186 L67
DNA Ligase Inhibitor
A DNA ligase inhibitor
GC18172 E7449
E7449; 2X-121
An inhibitor of PARP1, PARP2, and TNKS1/2