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Home >> Signaling Pathways >> DNA Damage/DNA Repair

DNA Damage/DNA Repair(DNA损伤/DNA修复)

Cat.No. 产品名称 Information
GC14230 K03861
AUZ454或者K03861,K03861
K03861 (K03861) 是一种 II 型 CDK2 抑制剂，Kd 为 8.2 nM。 K03861 (K03861) 通过与活化细胞周期蛋白的结合竞争抑制 CDK2 活性。
GC17232 P005672 hydrochloride
(4S,4AS,5AR,12AS)-4-(二甲基氨基)-1,4,4A,5,5A,6,11,12A-八氢-3,10,12,12A-四羟基-7-[(甲氧基甲基氨基)甲基]-1,11-二氧代-2-并四苯甲酰胺盐酸盐,Sarecycline hydrochloride
A tetracycline antibiotic
GC11654 Enocitabine
依诺他滨
A prodrug form of cytarabine
GC15399 Dp44mT
2-(二-2-吡啶基亚甲基)-N,N-二甲基肼基硫代甲酰胺
An iron chelator with antiproliferative effects
GC12193 6-Thio-dG
6-巯基-2'-脱氧鸟苷,β-TGdR; 6-Thio-2'-Deoxyguanosine
A purine nucleoside analog
GC16941 AZD6738
AZD6738
An ATR kinase inhibitor
GC13511 THZ2 A Cdk7 inhibitor
GC16914 MN 64 A TNKS inhibitor
GC12822 BML-210(CAY10433)
NphenylN'(2Aminophenyl)hexamethylenediamide, CAY10433
A potent, synthetic HDAC inhibitor
GC14367 UF 010 A class I HDAC inhibitor
GC12074 BG45 A selective HDAC3 inhibitor
GC10417 ACY-241
西他司他,Citarinostat
An HDAC6 inhibitor
GC16042 Chidamide
西达本胺,Chidamide impurity
An HDAC inhibitor
GC11360 ORY-1001
N1-(反式-2-苯基环丙基)环己烷-1,4-二胺二盐酸盐
An LSD1 inhibitor
GC14772 CCT244747
3-[(1R)-2-(二甲基氨基)-1-甲基乙氧基]-5-[[4-甲氧基-5-(1-甲基-1H-吡唑-4-基)-2-吡啶基]氨基]-2-吡嗪甲腈
A potent Chk1 inhibitor
GC10620 E3330
APX-3330

E3330 是脱嘌呤-脱嘧啶核酸内切酶/氧化还原效应因子 (APE1/Ref-1) 氧化还原结构域功能的小分子抑制剂（IC50，50 μmol/L）。
GC17601 TH287 A selective MTH1 inhibitor
GC12716 TH588 A selective MTH1 inhibitor
GC13541 G007-LK
Tankyrase 1/2 Inhibitor VI
A TNKS1/2 inhibitor
GC14707 Purvalanol A
NG-60
A selective inhibitor of cyclin-dependent kinases
GC12484 BRD73954 A dual inhibitor of HDAC6 and HDAC8
GC17833 Topotecan
拓扑替康; SKF 104864A; NSC 609669
Topotecan (SKF 104864A; NSC 609669) 是一种口服有效的拓扑异构酶 I 抑制剂。 Topotecan 在 G0/G1 和 S 期诱导细胞周期停滞并促进细胞凋亡。拓扑替康显示出抗癌活性。
GC16514 Penciclovir Sodium
VSA 671 sodium; BRL 39123A; BRL 39123D
An antiviral guanosine analog
GC16355 T 5601640
T5601640
An inhibitor of LIMK2
GC17613 SCH 51344
Ras/Rac Transformaton Blocker
An inhibitor of Ras/Rac transformation
GC13825 TA 01 An inducer of cardiomyocyte differentiation
GC11325 CX-4945 sodium salt
CX-4945 sodium salt
A potent, orally bioavailable CK2 inhibitor
GC15190 BMH-21 An RNA polymerase I inhibitor
GC11574 HPOB A potent and selective inhibitor of HDAC6
GC12106 SCR7 SCR7是一种DNA连接酶IV的小分子抑制剂，通过结合连接酶IV的DNA结合域（DBD）来抑制非同源末端连接（NHEJ）途径。
GC13892 C527 An inhibitor of the USP1/UAF complex
GC12348 Ro 3306
2-[[(噻吩-2-基)甲基]氨基]-5-[1-(喹啉-6-基)甲-(Z)-亚基]噻唑-4-酮
Ro 3306是一种ATP竞争性抑制剂，主要靶向CDK1/cyclin B1（K_i值为35nmol/L）和CDK1/cyclin A复合物（K_i值为110nmol/L）。
GC12971 CAY10603
BML-281
An exceptionally potent inhibitor of HDAC6
GC18094 Blasticidin S HCl
灭瘟素S盐酸盐
Blasticidin S HCl是一种从灰色链霉菌中分离的核苷类抗生素。
GC15238 Mupirocin
莫匹罗星; BRL-4910A; Pseudomonic acid
An antibiotic
GC14439 Santacruzamate A (CAY10683)
HDAC抑制剂,CAY-10683
A histone deacetylase inhibitor
GC16511 OTS964 A TOPK inhibitor
GC12304 OTS514 A TOPK inhibitor
GC11805 Toyocamycin
丰加霉素; Vengicide
Toyocamycin是一种腺苷类似物,是XBP1的抑制剂。
GC12786 ML216
N-[4-氟-3-(三氟甲基)苯基]-N'-[5-(4-吡啶基)-1,3,4-噻二唑-2-基]脲,CID-49852229
An inhibitor of the DNA repair enzyme Bloom helicase
GC11971 LY2857785 A Cdk9 inhibitor
GC13249 Rucaparib (free base)
瑞卡帕布; AG014699; PF-01367338
A PARP1 inhibitor
GC17067 LDC000067
(3-(6-(2-甲氧基苯基)嘧啶-4-基氨基)苯基)甲烷磺酰胺,LDC067
A Cdk9 inhibitor
GC10098 (S)-10-Hydroxycamptothecin
10-羟基喜树碱; 10-HCPT; 10-Hydroxycamptothecin
A DNA topoisomerase I inhibitor
GC12937 STF 083010
IRE1 Inhibitor I
An inhibitor of IRE1 endonuclease activity
GC12777 8-Chloroadenosine
8-氯腺嘌呤核苷

A nucleoside analog and an active metabolite of 8-chloro-cAMP
GC12131 L189 A DNA ligase inhibitor
GC10812 Compound 401 A dual inhibitor of mTOR and DNA-PK
GC15743 L-755,507 A selective β3-adrenergic receptor partial agonist
GC16582 DMNB
6-硝基藜芦醛,6-Nitroveratraldehyde
A photolabile H⁺-donor used in fluorescence imaging