Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC41950 16α-hydroxy Estrone
16ALPHA-羟基雌酚酮,16αOHE
A hydroxylated metabolite of estrone
GC41745 [Nle4,D-Phe7]-α-MSH (trifluoroacetate salt) A synthetic analog of α-MSH
GC41699 (Des-octanoyl)-Ghrelin (human) (trifluoroacetate salt) A peptide hormone
GC41671 (±)-Equol 4'-sulfate (sodium salt)
R,S-Equol 4'-Sulfate
A metabolite of (±)-equol
GC41321 17α,20β-Dihydroxy-4-pregnen-3-one
4-孕烷-17Α,20Β-二醇-3-酮,17α,20β-DHP，17α,20β-dihydroxy Progesterone
A maturation-inducing hormone
GC41300 17β-hydroxy Exemestane
亚甲基宝丹酮
An active metabolite of exemestane
GC41266 Pregnanediol-3-Glucuronide
Pregnanediol-3α-Glucuronide
A metabolite of progesterone
GC41187 Boldenone Cypionate
宝丹酮环戊丙酸酯
An Analytical Reference Standard
GC41153 Tibolone
替勃龙
A tissue-selective steroid with estrogenic and androgenic effects
GC40968 21-hydroxy Eplerenone
21-羟基依普利酮
A major metabolite of eplerenone
GC40960 20α-dihydro Prednisolone
20(R)-羟基泼尼松龙
A metabolite of prednisolone
GC40911 Glycine-β-muricholic Acid
Gly-MCA, GβMCA

An intestine-selective FXR antagonist
GC40867 Diflorasone Diacetate
醋酸双氟拉松；二醋酸二氟拉松
A corticosteroid
GC40833 (E/Z)-Endoxifen
N-去甲基-4-羟基-
An active metabolite of tamoxifen
GC40571 24(S),25-epoxy Cholesterol
(24S)-24,25-环氧胆固醇,24(S)-24,25-EC
An oxysterol
GC40528 11α-hydroxy Testosterone A CYP3A metabolite of testosterone
GC40465 9(S)-HETE
9(S)-Hydroxyeicosatetraenoic Acid
A monohydroxy fatty acid and RXRγ agonist
GC40464 9(R)-HETE
9(R)-Hydroxyeicosatetraenoic Acid
Enantiomer of (±)9-HETE; RXRγ activator
GC40454 16(S)-HETE
16(S)-Hydroxyeicosatetraenoic Acid
A potent inhibitor of proximal tubule ATPase activity
GC40341 Tetrahydro-11-deoxy Cortisol
四氢化-11-脱氧皮质醇
A metabolite of 11-deoxycortisol
GC40301 Tamoxifen N-oxide
他莫昔芬N-氧化物
A metabolite of tamoxifen
GC40293 Z3-Dodecenyl E2-butenoate A synthetic female sex pheromone
GC34887 Androstanolone acetate
雄诺龙醋酸酯
Androstanoloneacetate是一种雄激素配体，靶向作用于雄激素受体α(AR)。Androstanoloneacetate通过连接桥与cIAP1配体Bestatin结合从而形成PROTAC分子。
GC34862 WYC-209
4,5-二(羟甲基)-2-苯基-1H-咪唑
WYC-209是一种合成类视黄醇，能抑制恶性小鼠黑色素瘤肿瘤再生细胞(TRC)的增殖，IC50值为0.19μM。WYC-209主要细胞靶点是维甲酸受体(RARs)。
GC34824 T4-ATA S-isomer T4-ATAS-isomer是T4-ATA的S-异构体，是甲状腺激素的活性形式。
GC34822 T3-ATA S-isomer T3-ATAS-isomer是T3-ATA的S-异构体，是甲状腺激素的活性形式。
GC34740 PROTAC RAR Degrader-1 PROTACRARDegrader-1包含cIAP1配体结合基团，linker和RAR配体结合基团。在HT1080细胞中，PROTACRARDegrader-1降低RAR水平，30μM浓度时达到最大降解程度。同时，基于cIAP1的降解剂也被称为SNIPER。
GC34686 Nidufexor
LMB763

An FXR partial agonist
GP21262 Goserelin
Goserelin (ICI 118630) 是促性腺激素释放激素 (GnRH/LHRH) 的十肽类似物，可作为 GnRH 激动剂发挥作用。
GC19500 LY2795050 A κ-opioid receptor antagonist
GC40241 Fulvestrant-d3
ICI 182780-d3; ZD 9238-d3; ZM 182780-d3
An internal standard for the quantification of fulvestrant
GC40109 Ketoconazole-d3
2,2,2-三氮杂-1--1-[4-[4-[[（（2R，4S）-2-（2,4-二氯苯基）-2-（咪唑-1-基甲基）-1,3-二氧戊环-4-基]甲氧基]苯基]哌嗪-1-基]乙酮,(-)-Ketoconazol-d3; (-)-R 41400-d3
An internal standard for the quantification of ketoconazole
GC40094 all-trans Retinoic Acid-d5
atRA-d5, RA-d5, Vitamin A Acid-d5
An internal standard for the quantification of all-trans retinoic acid
GC40053 5α,6α-epoxy Cholestanol
胆固醇-5Α,6Α-环氧化物,NSC 18176
An oxysterol
GC40049 Glucocorticoid Resistance Inhibitor An inhibitor of glucocorticoid resistance
GC40024 Altenusin
细格菌素,Alutenusin
A fungal metabolite with diverse biological activities
GC34223 Dermorphin Analog DermorphinAnalog是Dermorphin的类似物。Dermorphin为两栖类皮肤中发现的天然七肽，为μ-阿片受体(μ-opioidreceptor)激动剂。
GC34173 LG-100064
4-[(5,6,7,8-四氢-3,5,5,8,8-五甲基-2-萘基)羰基]苯甲酸
LG-100064是一种类视黄醇X受体(retinoid-X-receptor(RXR))激动剂，对RXRα，RXRβ和RXRγ的EC50值分别为330nM，200nM和260nM；LG-100064可用于癌症研究。
GC34099 Buserelin Acetate Buserelin(INN)Acetate是一个GnRH的激动剂。
GC34005 Dehydroisoandrosterone 3-acetate (Dehydroepiandrosterone 3-acetate)
醋酸去氢表雄酮; Dehydroepiandrosterone 3-acetate; DHEA acetate
Dehydroepiandrosterone 3-acetate 是一种睾酮/雌激素前体和已知的脊椎动物攻击性调节剂。
GC34001 Gonadorelin acetate
醋酸戈那瑞林
A tropic hormone
GC33845 Protirelin Acetate (TRF Acetate)
醋酸普罗瑞林; Thyrotropin-releasing-hormone acetate; TRH acetate
Protirelin (Thyroliberin, Lopremone, Synthetic TRH, Thyrotropin-releasing hormone, Rifathyroin) is a tripeptide that stimulates the release of thyrotropin and prolactin.
GC33784 β-Casomorphin, human (Human β-casomorphin 7)
Human β-casomorphin 7
是一种阿片肽，作为阿片受体的激动剂。
GC33764 Eprotirome (KB2115)
伊罗替罗,KB2115
A thyroid hormone mimetic
GC33736 β-Casomorphin, bovine (β-Casomorphin-7 (bovine))
Β-酪啡肽-7,β-Casomorphin-7 (bovine); Bovine β-casomorphin-7
β-Casomorphin, bovine (β-Casomorphin-7 (bovine)) (β-Casomorphin-7 (bovine) ) 是一种阿片肽，在阿片受体结合试验中的 IC50 为 14 μM。
GC33673 24-Hydroxycholesterol
24-羟基胆固醇

24-Hydroxycholesterol是一种天然的固醇类物质，是n-甲基-d-天门冬氨酸受体(NMDA)和转录因子LXR的激活剂。
GC33467 Cetrorelix Acetate (SB-075 acetate)
醋酸西曲瑞克; SB-75 acetate
A synthetic peptide GnRHR antagonist
GC33315 AGN 194078 AGN194078是一个有选择性的RARα激动剂，其Kd和EC50值分别为3和112nM。
GC33224 Proxalutamide (GT0918)
GT0918; Pruxelutamide
Proxalutamide (GT0918) is a second-generation androgen receptor antagonist that binds to the ligand-binding domain of AR with an IC50 of 32 nM in the AR competive binding assays.
GC33081 [D-Ala2]leucine-enkephalin
(D-ALA2)-亮氨酸脑啡肽
[D-Ala2]leucine-enkephalin是一种δ阿片类(deltaopioid)激动剂，是一种能长效抗降解的亮氨酸脑非肽。