Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC16840 ARN-509
阿帕鲁胺,ARN 509; ARN509
An androgen receptor antagonist
GC10372 AZD3514 A SARD
GC10596 T0901317
N-(2,2,2-三氟乙基)-N-[4-[2,2,2-三氟-1-羟基-1-(三氟甲基)乙基]苯基]苯磺酰胺
Selective agonist for LXRα and LXRβ
GC15459 Tazarotene
他扎罗汀; AGN 190168
A retinoid prodrug
GC15166 Perindopril Erbumine
培哚普利叔丁胺; Perindopril tert-butylamine salt; S-9490 erbumine
An orally active ACE inhibitor
GC16978 Candesartan
坎地沙坦; CV 11974
An AT₁ receptor antagonist
GC17094 Acitretin
阿维A; Ro 10-1670
A retinoid
GC13685 Andarine
S-4
A selective androgen receptor modulator
GC11829 ADL5859 HCl
N,N-二乙基-4-(5-羟基螺[2H-1-苯并吡喃-2,4'-哌啶]-4-基)苯甲酰胺盐酸盐
A δ-opioid receptor agonist
GC10893 Dutasteride
度他雄胺; GG 745; GI 198745
An inhibitor of steroid 5α-reductase
GC12271 Bicalutamide
比卡鲁胺
A non-steroidal antiandrogen
GC10257 Losartan Potassium (DuP 753)
氯沙坦钾; DuP-753 potassium
A potent, synthetic AT₁ receptor antagonist
GC10610 Adapalene
阿达帕林; CD271
An RARβ and RARγ agonist
GC10726 Letrozole
来曲唑; CGS 20267
Letrozole（来曲唑; CGS 20267）是一种口服活性非甾体类选择性芳香酶抑制剂，IC₅₀为11.5nM。
GC11813 Exemestane
依西美坦; FCE 24304; EXE
A third generation, irreversible steroidal aromatase inhibitor
GC16248 Finasteride
非那雄胺; MK-906
An inhibitor of 5α-reductase type II
GC18000 Fulvestrant (ICI 182,780)
氟维司群
Fulvestrant是一种选择性雌激素受体(ER)拮抗剂。
GC10064 Flurizan
R-氟比洛芬; (R)-Flurbiprofen; MPC7869
A COX-inactive enantiomer of flurbiprofen
GC11544 Toremifene
托瑞米芬,Acapodene;Chlortamoxifen;Farestone;GTx 006;Z-Toremifene
托瑞米芬（Z-托瑞米芬）是一种用于预防骨质疏松症的第二代选择性雌激素受体调节剂（SERM）。
GC16847 Tanaproget
NSP-989;NSP 989;NSP989
Tanaproget (NSP-989) 是一种新型非甾体孕酮受体激动剂，与参考甾体孕激素相比，它可以以更高的相对亲和力与来自各种物种的 PR 结合。
GC13984 Tamibarotene
他米巴罗汀; Am 80
A selective RARα agonist
GC17063 Talarozole
他拉罗唑; R115866
Talarozole (R115866) 是一种口服全身性全反式维甲酸代谢阻断剂 (RAMBA)，可增加内源性全反式维甲酸 (RA) 的细胞内水平。
GC12903 Sobetirome
GC-1; QRX-431
An agonist of TRβ
GC12933 RU 58841
RU58841; RU-58841
A non-steroidal antiandrogen
GC17200 Nestoron
醋酸烯诺孕酮; ST-1435; Elcometrine
A synthetic progestin
GC16177 Methylnaltrexone Bromide
Relistor
Antagonist of peripherally acting μ-opioid
GC17874 Matrine
苦参碱; Matridin-15-one; Vegard; α-Matrine
苦参碱（Matrine）是一种存在于槐属植物中的生物碱，可作为 kappa 阿片受体和µ-受体激动剂。
GC10076 Leuprolide Acetate
醋酸亮丙瑞林,Leuprorelin acetate;Lupron
A synthetic GnRH receptor agonist
GC17624 JDTic 2HCl
(3R)-1,2,3,4-四氢-7-羟基-N-[(1S)-1-[[(3R,4R)-4-(3-羟基苯基)-3,4-二甲基-1-哌啶基]甲基]-2-甲基丙基]-3-异喹啉甲酰胺盐酸盐
JDTic (dihydrochloride) 是一种有效的 kappa-阿片受体 (KOR) 拮抗剂，可阻断 κ-激动剂 U50, 488 诱导的镇痛作用。
GC17939 JDTic JDTic 是 κ-阿片受体的高选择性拮抗剂；不影响 μ- 或 δ-阿片受体。
GC16964 GW3965
3-[3-[[[2-氯-3-(三氟甲基)苯基]甲基](2,2-联苯基乙基)氨基]丙氧基]苯乙酸盐酸盐,GW 3965;GW-3965
An orally-active agonist of LXRα and LXRβ
GC17143 Fenretinide
芬维A胺; 4-HPR
A synthetic retinoic acid derivative
GC10852 Bazedoxifene acetate
醋酸巴多昔芬,Viviant, WAY-140424, WAY-TES 424, Conbriza, TSE-424,
A selective estrogen receptor modulator
GC14883 Bazedoxifene
巴多昔芬; TSE-424
Bazedoxifene (TSE-424) 是一种口服的、可渗透 BBB 的非甾体选择性雌激素受体调节剂 (SERM)，对 ERα 和 ERβ 的 IC50 分别为 23 nM 和 99 nM。巴多昔芬可用于骨质疏松症的研究。 Bazedoxifene 还作为 IL-6/GP130 蛋白-蛋白相互作用的抑制剂，可用于胰腺癌的研究。
GC15926 BAN ORL 24
(2R)-1-苄基-N-(3-螺[异苯并呋喃-1(3H),4'-哌啶]-1'-丙基)-2-吡咯烷甲酰胺,BAN-ORL-24;BAN ORL-24
A nociceptin receptor antagonist
GC10547 ASC-J9
二甲基姜黄素,GO-Y025; Dimethylcurcumin; ASC J9; GO Y025
A selective enhancer of AR degradation
GC12619 Alvimopan dihydrate
爱维莫潘; ADL 8-2698 dihydrate; LY 246736 dihydrate
A μ-opioid receptor antagonist
GC17623 Alvimopan
爱维莫潘; ADL 8-2698; LY 246736
A μ-opioid receptor antagonist
GC12374 Alarelin Acetate
醋酸阿拉瑞林,Alarelin
A peptide agonist of GnRH
GC13959 Adarotene
(2E)-3-(4'-羟基-3'-金刚烷-1-基[1,1'-联苯]-4-基)-2-丙烯酸,ST 1926;ST-1926;ST1926
An atypical retinoid
GC12791 3,3'-Diindolylmethane
3,3'-二吲哚甲烷,diindolylmethane, 3,3'-Methylenediindole,DIM,Arundine,HB236
A phytochemical with antiradiation and chemopreventative effects
GC17557 17 alpha-propionate
克拉司酮,17α-propionate; CB-03-01
A peripherally selective androgen receptor antagonist
GC15373 (E)-2-Decenoic acid
反式-2-癸烯酸,trans-2-Decenoic acid
An unsaturated fatty acid found in royal jelly
GC15382 Isotretinoin
异维A酸; 13-cis-Retinoic acid
A retinoid
GC16649 TAK-700 (Orteronel) A non-steroidal inhibitor of the 17,20-lyase activity of CYP17A1
GC16223 Captopril
卡托普利; SQ 14225
An ACE inhibitor
GC12385 MDV3100 (Enzalutamide)
恩杂鲁胺; MDV3100
MDV3100(enzalutamide) 是第二代 AR 拮抗剂，在 LNCaP 前列腺细胞中的 IC50 为 36nM。
GN10213 Sinomenine Hydrochloride
盐酸青藤碱; Cucoline hydrochloride
A natural anti-inflammatory alkaloid
GN10268 Triptophenolide
雷酚内酯; Hypolide; (+)-Triptophenolide
A diterpenoid with antiandrogenic activity
GN10024 Saikosaponin A
柴胡皂苷 A
A triterpenoid saponin with diverse biological activities