Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC49631 Fluocortolone
氟可龙
A glucocorticoid
GC49629 6β-hydroxy Prednisolone
泼尼松龙杂质D
A metabolite of prednisolone
GC49611 21-Deoxycortisol-d8
21-Dehydrohydrocortisone-d8
An internal standard for the quantification of 21-deoxycortisol
GC49609 2-bromo 17β-Estradiol
2-溴雌二醇
A synthetic steroid and inhibitor of estrogen 2-hydroxylase
GC49592 Sermorelin (acetate)
易吸潮
A growth hormone-releasing hormone analog
GC49574 Somatostatin-28 (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) A cyclic neuropeptide hormone
GC49563 Fenhexamid
环酰菌胺,KBR 2738
A fungicide
GC49562 4-methoxy Estrone
4-甲氧基雌酮
An active metabolite of estrone
GC49542 5α-Androstan-3β-ol
5Α-雄甾烷-3Β-醇
A steroidal androgen
GC49520 (S)-Equol
雌马酚
An estrogen receptor β agonist
GC49475 Triptorelin (trifluoroacetate salt)
D-Trp6-GnRH, D-Trp6LH-RH, AY 25650, BIM 21003, CL 118,53, Wy 42422, Wy 42462
A synthetic GNRH peptide agonist
GC49459 Desmopressin (trifluoroacetate salt)
Adiuretin, DDAVP
A vasopressin receptor agonist
GC63764 7-α-Methylthio Spironolactone-D3
GC63755 Exemestane-D2
FCE 24304-D2; EXE-D2
Exemestane-D2 (FCE 24304-D2) 是 Exemestane 的氘代物。Exemestane (FCE 24304) 是一种选择性，不可逆和具有口服活性的甾体芳香酶 (aromatase) 抑制剂，对人胎盘和大鼠卵巢芳香酶的 IC50 分别为 30 nM 和 40 nM。Exemestane 可用于激素依赖性乳腺癌研究。
GC63686 Naloxone methiodide Naloxone methiodide 是一种外周限制性、非选择性和竞争性阿片受体 (opioid receptor) 拮抗剂。Naloxone methiodide 不能穿透血脑屏障。
GC63595 NH-3 NH-3 是一种具有口服活性的，可逆甲状腺激素受体 (THR) 拮抗剂，IC50 为 55 nM。NH-3 是选择性甲状腺素 GC-1 的衍生物，可抑制甲状腺激素与其受体的结合，并抑制辅因子募集。
GC63579 Linuron
利谷隆
A phenylurea herbicide
GC63431 DPDPE TFA DPDPE TFA 是一种阿片肽，是一种具有抗惊厥作用的选择性阿片受体 (DOR) 激动剂。
GC63402 Rezvilutamide
SHR3680
Rezvilutamide (SHR3680) 雄激素受体 (androgen receptor) 的拮抗剂。Rezvilutamide (SHR3680) 可用于前列腺癌的研究。
GC63292 (rac)-PF-998425 (rac)-PF-998425 是一种有效、选择性的非甾体雄激素受体 (AR) 拮抗剂。(rac)-PF-998425 在 AR 结合和细胞分析中的 IC50 值分别为 26 和 90 nM。(rac)-PF-998425 具有用于研究雄激素性脱发的潜力。
GC19892 Sodium chenodeoxycholate
鹅脱氧胆酸钠
A primary bile acid
GC63217 Testosterone undecanoate
十一酸睾酮,Testosterone undecylate
Testosterone undecanoate是一种口服的合成代谢类固醇睾酮的酯前体药，可作为一种有效的睾酮替代疗法。
GC63200 Spiradoline
螺朵林,U-62066
Spiradoline (U-62066) 是一种芳基乙酰胺，是一种选择性 kappa 阿片受体 (κ-opioid receptor, KOR) 激动剂，在豚鼠中的 Ki 为 8.6 nM。Spiradoline 对 μ 和 δ 受体的 Ki 值分别为 252 nM 和 9400 nM。Spiradoline 具有强效的利尿，止痛，抗心律失常，镇咳，神经保护作用，并易于穿过血脑屏障。
GC63115 Nociceptin (1-13), amide TFA Nociceptin (1-13), amide TFA 是一种有效的阿片受体 ORL1 (OP4) 受体激动剂，对小鼠输精管 pEC50 值为 7.9，与大鼠前脑膜结合的 Ki 值为 0.75 nM。
GC63096 Nandrolone phenylpropionate
苯丙酸诺龙
Nandrolone phenylpropionate，19-nortestosterone 的衍生物，是一种合成代谢类固醇，可促进蛋白质合成。Nandrolone phenylpropionate 用于缓解组织分解代谢，可以用于骨质疏松症和特纳综合征的研究。
GC63072 Methyl-6-alpha-Naltrexol
Methyl-6-alpha-Naltrexol 是甲基纳曲酮 (MNTX) 的代谢物 (metabolite)。Methyl-6-alpha-Naltrexol 是一种选择性的 mu-阿片受体 (mu-opioid receptor) 拮抗剂，在胃肠道组织中起外周作用的受体拮抗剂作用。
GC63066 Methenolone acetate
美替诺龙醋酸酯,Methenolone acetate

Metenolone醋酸盐是一种长效的蛋白同化激素，具有较低的雄激素特性。IC50 value:Target:Metenolone醋酸盐是一种天然存在的化合物，在驯养的怀孕猫科肾上腺腺体内发现。Metenolone醋酸盐用于口服给药。Methenolone醋酸盐可抑制下丘脑 - 垂体 - 性腺通路。[1] Methenolone醋酸盐作为口服制剂时，Methenolone不是17-α-烷基化，而是1-甲基化，便于提高口服生物利用度，且降低肝脏应力。[2]
GC62992 Glutaurine
磺乙谷酰胺,Litoralon
A dipeptide
GC62761 1α-Hydroxy-3-epi-vitamin D3 1α-Hydroxy-3-epi-vitamin D3 是 1alpha,25-dihydroxyvitamin D3 的天然代谢物，是甲状旁腺激素 (?PTH?) 分泌的有效抑制剂
GC49427 3,5-Diiodo-L-thyronine
3,5-二碘-L-甲状腺素,3,5-Diiodo-L-thyronine
A thyroid hormone metabolite
GC49423 Metanephrine-d3 (hydrochloride)
DL-Metanephrine-d3
An internal standard for the quantification of metanephrine
GC49408 Ramipril Diketopiperazine Acid
雷米普利杂质K
A potential impurity found in commercial preparations of ramipril
GC49399 N-Desbutyl Dronedarone (hydrochloride)
N-[2-丁基-3-[4-[3-(丁基氨基)丙氧基]苯甲酰基]-5-苯并呋喃基]甲磺酰胺盐酸盐,SR35021 hydrochloride
An active metabolite of dronedarone
GC49393 all-trans-13,14-Dihydroretinol A metabolite of all-trans retinoic acid
GC49391 7α-Thiospironolactone
Deacetylspironolactone, Mercaptospironolactone, SC-24813, 7α-Thio-SL
An active metabolite of spironolactone
GC49389 Tritylolmesartan Medoxomil
三苯甲基奥美沙坦酯
An intermediate in the synthesis of olmesartan medoxomil
GC49385 Halometasone
卤米松
A synthetic corticosteroid
GC49342 Glucagon-d9 (trifluoroacetate salt) An internal standard for the quantification of glucagon
GC49329 Turkesterone (hydrate) A phytoecdysteroid with diverse biological activities
GC49326 5β-Dihydroprogesterone
5Β-二氢孕酮
A progesterone receptor agonist and metabolite of progesterone
GC49321 AZ-GHS-22 An inverse agonist of GHS-R1a
GC49306 Isopimaric Acid
异海松酸
A diterpenoid resin acid
GC49303 Ganoderic Acid DM
灵芝酸 DM
A triterpenoid with diverse biological activities
GC49254 Estrone-3-Glucuronide (sodium salt hydrate)
E1G, Estrone Glucuronide, Estrone β-D-Glucuronide
A metabolite of 17β-estradiol
GC49207 Lumisterol 3
光甾醇 3; 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C
A photoisomer of previtamin D₃
GC49206 7α-hydroxy Dehydroepiandrosterone
7-羟基去氢表雄酮
An active metabolite of dehydroepiandrosterone
GC49189 (E/Z)-4-hydroxy Tamoxifen-d5
Afimoxifene-d5, 4-OHT-d5
An internal standard for the quantification of (E/Z)-4-hydroxy tamoxifen
GC49180 3-epi-25-hydroxy Vitamin D3
3-EPI-25-羟基维生素D3
The C-3 epimer of 25-hydroxy vitamin D₃
GC49176 5β-Tetrahydrocortisol
NSC 57431
An endogenous metabolite of cortisol
GC49172 2-hydroxy Estrone
2-羟雌甾酮,Catecholestrone
An active metabolite of estrone