Endocrinology and Hormones(内分泌和激素)

Endocrinology and Hormones

The endocrine system is an information signaling system that coordinates most bodily functions. It senses environmental changes and secretes corresponding hormones to coordinate metabolism, maintain homeostasis, and regulate growth and development.read more

Products for Endocrinology and Hormones

Cat.No. 产品名称 Information
GC45589 Urocortin III (human) (trifluoroacetate salt) A neuropeptide hormone
GC45588 Urocortin II (mouse) (trifluoroacetate salt) A neuropeptide hormone
GC45584 Triamcinolone acetonide-d7 An internal standard for the quantification of triamcinolone acetonide
GC45567 SR 1903 A modulator of RORγ and LXR receptors
GC45530 Norgestrel-d6
左炔诺孕酮 d6
An internal standard for the quantification of norgestrel
GC45529 Nonapeptide-1 (acetate)
Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2, MPFRWFKPV-NH2, 153N-6
An MC1R antagonist
GC45490 Kisspeptin-54 (human) (trifluoroacetate salt)
Metastin (human)
A peptide ligand of GPR54
GC45466 Glyco-Obeticholic Acid
奥贝胆酸杂质8
An active metabolite of obeticholic acid
GC45464 GLP-2 (rat) (trifluoroacetate salt)
Glucagon-like Peptide 2
A gut peptide hormone antagonist of GLP-2R
GC45463 GLP-2 (1-34) (human) (trifluoroacetate salt)
Glucagon-like Peptide 2 (1-34)
A synthetic form of the peptide GLP-2
GC45462 GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
Glucagon-like Peptide 1 (1-36) amide (human, rat)
A peptide hormone
GC45459 GHRP-6 (acetate)
生长激素释放肽-6
A growth hormone secretagogue and GHS-R agonist
GC45455 Fluticasone 17β-Carboxylic Acid
氟米松酸
An intermediate in the synthesis of fluticasone propionate
GC45452 Estrone-d2
雌酚酮-D2,E1-d2; Oestrone-d2
An internal standard for the quantification of estrone
GC45451 Estrone 3-methyl ether
3-甲氧基雌酮
A synthetic estrogen
GC45450 Estriol-d2
雌三醇 d2
An internal standard for the quantification of estriol
GC45413 Cridanimod (sodium salt)
吖啶酮乙酸钠
An inducer of type I interferon production
GC45409 Ciclesonide-d7
环索奈德 d7
An internal standard for the quantification of ciclesonide
GC45374 ACTH (1-17) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
Adrenocorticotropic Hormone (1-17), SYSMEHFRWGKPVGKKR-OH
A peptide fragment of ACTH
GC45372 ACTH (1-13) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
SYSMEHFRWGKPV-OH
A peptide fragment of ACTH
GC38005 β-Endorphin, equine β-Endorphin, equine 为具有镇痛作用的内源性阿片类多肽。
GC37913 Vitamin A
维生素A
An intermediate in retinol metabolism
GC37829 Trimebutine maleate
马来酸曲美布汀
An opioid receptor agonist
GC37732 Taltirelin acetate
TA-0910 acetate
Taltirelin acetate (TA-0910 acetate) 是一种促甲状腺激素释放激素受体 (TRH-R) 超激动剂，IC50 值为 910 nM，刺激细胞溶质Ca2+ 浓度增加 (Ca2+ 释放) 的 EC50 值为 36 nM。
GC37691 Stigmasterol glucoside
豆甾醇葡萄糖苷
Stigmasterol glucoside 是从 P. urinaria 分离出的一种甾醇，具有高抗氧化和高抗炎活性，能作为抑制剂 5α-reductase 的抑制剂，IC50 值为 27.2 ?M。
GC37687 Stanolone benzoate
17-安息香酸雄甾醇酮
Stanolone benzoate (Androstanolone benzoate) 是一种合成的雄激素和合成代谢类固醇。
GC37630 Sevelamer
司维拉姆
Sevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
GC37525 RGX-104 free Acid
Abequolixron
RGX-104 free Acid 是具有口服生物活性的、有效的肝X核激素受体 (LXRβ) 激动剂，通过ApoE基因的转录激活调节先天免疫。
GC36981 PROTAC AR Degrader-4 PROTAC AR Degrader-4 包含 cIAP1 配体结合基团，linker 和雄激素受体 (AR) 配体结合基团。基于 cIAP1 的降解剂也被称为 SNIPER。
GC36947 Porcine dynorphin A(1-13)
强啡肽A(1-13),Dynorphin A Porcine Fragment 1-13
Porcine dynorphin A (1-13) 是一个有效的内源性阿片受体 (κ opioid receptor) 激动剂，在生理浓度下它有镇痛作用。
GC36820 Ostarine Ostarine (GTx-024, MK-2866, Enobosarm) is a selective androgen receptor modulator (SARM) with Ki of 3.8 nM, and is tissue-selective for anabolic organs. Phase 3.
GC36778 N-terminally acetylated Leu-enkephalin
Ac-L-Tyr-Gly-Gly-L-Phe-D-Leu-COOH
N-terminally acetylated Leu-enkephalin 是N-末端乙酰化的 Leu-enkephalin。Leu-enkephalin是一种五氨基酸的内源性肽，作为阿片受体的激动剂。
GC36689 Nalfurafine hydrochloride
盐酸纳呋拉啡; TRK-820 hydrochloride
An Analytical Reference Standard
GC36621 MK-0773
PF-05314882
MK-0773 是一种选择性雄激素受体调节剂 (selective androgen receptor modulators)，与 AR 结合，IC50 值为 6.6 nM。
GC36562 MCOPPB triHydrochloride
MCOPPB 3HCl
MCOPPB 3Hcl 是一种伤害感受肽受体激动剂，pKi为10.07；其他阿片受体的活性较弱。
GC36508 LY-2940094
BTRX-246040
LY-2940094 是一种口服有效的选择性 nociceptin 受体 (NOP 受体) 拮抗剂，对 NOP 受体具有高亲和力(Ki 为 0.105 nM) 和拮抗活力 (Kb=0.166 nM)。LY-2940094 可降低动物模型的自身给药酒精依赖。
GC36499 LXRβ agonist-2 LXRβ agonist-2 是一种高效 β 选择性肝 X 受体 (LXRβ) 激动剂，EC50为 7 nM，其选择性是 LXRα (EC50=200 nM) 的 28.5 倍，用于治疗动脉粥样硬化。
GC36487 L-Thyroxine sodium salt pentahydrate
L-甲状腺素钠五水合物; Sodium levothyroxine pentahydrate
A synthetic form of thyroxine
GC36479 Loperamide hydrochloride
盐酸洛哌丁胺; R-18553 hydrochloride
An Analytical Reference Standard
GC36465 Liothyronine An thyroid hormone which binds to TRβ1, and activates its activity
GC36344 Isosilybin B
异水飞蓟宾B
Isosilybin B，一种从 silymarin 中分离的黄酮木脂素，具有抗前列腺癌 (PCA) 活性，抑制癌细胞增殖，诱导 G1 期阻滞和凋亡。Isosilybin B 引起雄激素受体降解。
GC36180 Goserelin acetate
醋酸戈舍瑞林; ICI-118630 acetate
A synthetic GNRH agonist
GC35986 Endomorphin 2 TFA
内吗啡肽 2 三氟乙酸盐
Endomorphin 2 TFA，一种高度选择性的高亲和力 μ-opioid 受体激动剂，对 kappa3 结合位点具有高亲和力，Ki 为 20 到 30 nM 之间。
GC35919 Dynorphin B (1-13) (TFA)
强啡肽 B (1-13) 三氟乙酸盐
Dynorphin B (1-13) TFA 是一种阿片样 κ 受体 (κ-opioid receptor) 激动剂。
GC35918 Dynorphin A 1-10 Dynorphin A (1-10) 是一种内源性的阿片样神经肽，与 κ 阿片受体 (κ-opioid receptor) 结合。Dynorphin A (1-10) 也阻断 NMDA 激活的电流，IC50 为 42.0 μM。
GC35917 Dynorphin A (1-10) TFA Dynorphin A (1-10) (TFA) 是一种内源性的阿片样神经肽，与 κ 阿片受体 (κ-opioid receptor) 结合。Dynorphin A (1-10) (TFA) 也阻断 NMDA 激活的电流，IC50 为 42.0 μM。
GC35828 Degarelix
地加瑞克
A synthetic GNRHR antagonist
GC35805 DAMGO (TFA) DAMGO (DAGO) is a potent and selective μ opioid receptor agonist with ki of 17 nM.
GC35638 Cebranopadol ((1α,4α)stereoisomer)
GRT6005 (1α,4α)stereoisomer
Cebranopadol (1α,4α)stereoisomer 是 cebranopadol 的立体异构体，活性较低。Cebranopadol 是 ORL-1 的有效激活剂。
GC35637 Cebranopadol
GRT6005

A nociceptin-, µ-, ĸ-, and δ-opioid receptor agonist