Aromatase(芳香酶)

Aromatase is an enzyme which belongs to the cytochrome p450 superfamily. It localizes on the endoplasmic reticulum of estrogen producing cell and catalyzes the final step of estrogen biosynthesis, converting androgen to estrogens.

Products for Aromatase

Cat.No. 产品名称 Information
GC63755 Exemestane-D2
FCE 24304-D2; EXE-D2
Exemestane-D2 (FCE 24304-D2) 是 Exemestane 的氘代物。Exemestane (FCE 24304) 是一种选择性，不可逆和具有口服活性的甾体芳香酶 (aromatase) 抑制剂，对人胎盘和大鼠卵巢芳香酶的 IC50 分别为 30 nM 和 40 nM。Exemestane 可用于激素依赖性乳腺癌研究。
GC38682 Flavanone
黄烷酮
Flavanones (2,3-Dihydroflavone, 4-Flavanone, 2-Phenyl-4-chromanone, 2-Phenylchroman-4-one) show strong antioxidant and radical scavenging activity, and appear to be associated with a reduced risk of certain chronic diseases, the prevention of some cardiovascular disorders, and certain kinds of cancer. Flavanones also exhibit antiviral, antimicrobial, and anti-inflammatory activities, beneficial effects on capillary fragility, and an ability to inhibit human platelet aggregation, anti-ulcer, and anti-allergenic properties.
GC19151 Fadrozole
法倔唑; CGS 16949A free base; (Rac)-FAD286
A non-steroidal aromatase inhibitor
GC18301 Fadrozole (hydrochloride)
盐酸法倔唑,CGS 16949A; (Rac)-FAD286 hydrochloride
A non-steroidal aromatase inhibitor
GC12890 α-Naphthoflavone
α-萘黄酮
A flavone that modulates xenobiotic metabolism
GC12140 Endoxifen
Z-因多昔芬
Endoxifen Z-异构体是最重要的他莫昔芬代谢物，负责在表达雌激素受体-α (ERα) 的乳腺癌细胞中引发该药物的抗雌激素作用。
GC12815 Formestane
福美司坦
An Analytical Reference Standard
GC16433 Aminoglutethimide
氨鲁米特,DL-Aminoglutethimide
An aromatase inhibitor
GC10256 Anastrozole
阿那曲唑; ZD1033
An aromatase/CYP19A1 inhibitor
GC10726 Letrozole
来曲唑; CGS 20267
Letrozole（来曲唑; CGS 20267）是一种口服活性非甾体类选择性芳香酶抑制剂，IC₅₀为11.5nM。
GC11813 Exemestane
依西美坦; FCE 24304; EXE
A third generation, irreversible steroidal aromatase inhibitor
GN10457 Oleuropein
橄榄苦苷
A polyphenol