5-HT Receptor(5-羟色胺受体)
5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.
Products for 5-HT Receptor
- Cat.No. 产品名称 Information
- GC15092 BGC 20-761 BGC 20-761 是一种选择性 5-HT6 和多巴胺受体拮抗剂(人受体 Ki 值:5-HT6 (20 nM)、5-HT2A (69 nM)、D2 (140 nM))。
- GC12744 NPS ALX Compound 4a dihydrochloride NPS ALX Compound 4a dihydrochloride 是一种有效的选择性 5-hydroxytryptamine6 (5-HT6) 受体拮抗剂,IC50 为 7.2 nM,Ki 为 0.2 nM。
- GC15660 SB 399885 hydrochloride A 5-HT6 receptor antagonist
- GC12524 SB 699551 5-ht5a受体拮抗剂
- GC13583 CJ 033466 CJ 033466 是一种新型选择性 5-HT4 受体部分激动剂,EC50 为 9 nM,具有促胃动力作用。
- GC12657 LY 334370 hydrochloride A 5-HT1F receptor agonist
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GC10919
LY 272015 hydrochloride
1-(3,4-二甲氧基苄基)-6-甲基-2,3,4,9-四氢-1H-吡啶并[3,4-B]吲哚盐酸盐
A 5-HT2B receptor antagonist - GC14607 1-Methylpsilocin 5-HT2C agonist,potent and selective
- GC14195 LP 12 hydrochloride LP 12 hydrochloride (compound 21) 是一种有效的选择性 5-HT7 受体激动剂,Ki 为 0.13 nM。
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GC17260
Ro 04-6790
4-氨基-N-[2,6-双(甲基氨基)-4-嘧啶基]苯磺酰胺
A 5-HT6 receptor antagonist -
GC16324
Nefazodone hydrochloride
萘法唑酮盐酸盐,BMY-13754; MJ-13754-1
A serotonin, norepinephrine, and dopamine reuptake inhibitor -
GC13109
Fananserin
法南色林,RP 62203
Fananserin (RP 62203) 是一种口服有效的选择性 5-hydroxytryptamine2 (5-HT2) 受体拮抗剂,对大鼠 5-HT2A 受体的 Ki 值为 0.37 nM。 - GC11308 L-703,664 succinate 5-HT1D receptor agonist
- GC11490 TCB-2 5-HT2A受体激动剂
- GC18112 LP 44 A selective 5-HT7 receptor agonist
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GC11929
Melperone hydrochloride
1-[3-(对氟苯甲酰基)丙基]-4-甲基哌嗪氯化物
An atypical antipsychotic - GC16045 EMD 386088 hydrochloride EMD 386088 hydrochloride 是一种有效的血清素 6 受体 (5-HT6R) 激动剂。
- GC17714 PNU 22394 hydrochloride 5-HT2C agonist and partial 5-HT2A/5-HT2B agonist
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GC14583
R 59-022
DKGI-I; Diacylglycerol kinase inhibitor I
A DGK inhibitor -
GC12300
WAY 629 hydrochloride
5-HT2C agonist
- GC17219 SDZ 205-557 hydrochloride 5-HT3/5-HT4 receptor antagonist
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GC17525
AS 19
A 5-HT7 receptor agonist
- GC12383 SB 258585 hydrochloride A selective 5-HT6 receptor antagonist
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GC13883
Ritanserin
利坦丝林,R 55667
A potent 5-HT2A receptor antagonist - GC15135 Ro 60-0175 fumarate A 5-HT2 receptor agonist
- GC14030 Altanserin hydrochloride 5-HT2A receptor antagonist
- GC11980 WAY 161503 hydrochloride A 5-HT2C receptor agonist
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GC17343
Zacopride hydrochloride
查可必利盐酸盐
Zacopride hydrochloride 是一种高效的 5-HT3 受体拮抗剂,对 5-HT3 和 5-HT4 受体的 Kis 分别为 0.38 和 373 nM。 -
GC17706
R-96544 hydrochloride
R-96544盐酸盐
5-HT2 receptor antagonist - GC10310 SB 206553 hydrochloride A 5-HT2C and 5-HT2B receptor antagonist
- GC15248 GR 125487 sulfamate 5-HT4 receptor antagonist
- GC14516 Mesulergine hydrochloride 5-HT2A and 2C receptor antagonist
- GC13607 LY 215840 5-HT2/5-HT7 receptor antagonist
- GC17140 GR 127935 hydrochloride A 5-HT1B and 5-HT1D receptor antagonist
- GC13298 NAS-181 NAS181 是一种有效的、选择性的大鼠 5-HT1B 受体拮抗剂,Ki 为 47 nM。
- GC16556 SB 221284 SB 221284 是一种选择性 5-HT2C/2B 受体拮抗剂,对 5-HT2A、5-HT2B 和 5-HT2C 受体的 pKi 值分别为 6.4、7.9 和 8.6。
- GC14347 SB 228357 SB 228357 是一种选择性、有效的口服活性 5-HT2C/2B 受体拮抗剂,5-HT2A、5-HT2B 和 5-HT2C 的 pKi 值分别为 6.9、8.0 和 9.0。
- GC12803 SB 204741 A 5-HT2B receptor antagonist
- GC11624 GR 113808 A 5-HT4 antagonist
- GC16653 CP 94253 hydrochloride A 5-HT1B receptor agonist
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GC12735
SDZ SER 082 fumarate
SDZSER082富马酸盐
5-HT2B/2C receptor antagonist - GC15551 SB 216641 hydrochloride A 5-HT1B receptor antagonist
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GC13438
SB 224289 hydrochloride
SB-224289A
A 5-HT1B receptor inverse agonist -
GC15630
SR 57227 hydrochloride
SR57227盐酸盐
A 5-HT3 receptor agonist -
GC11231
BW 723C86 hydrochloride
BW723C86盐酸盐
A selective HT2B receptor agonist - GC17524 GR 55562 dihydrochloride 5-HT1B (5-HT1Dβ) silent antagonist
- GC10068 CP 93129 dihydrochloride A 5-HT1B receptor agonist
- GC15979 RS 16566 dihydrochloride (R)-zacopride 结合位点的配体
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GC16553
N-Desmethylclozapine
N-去甲基氯氮平; Norclozapine; Desmethylclozapine; Normethylclozapine
An active metabolite of clozapine - GC14696 RS 67506 hydrochloride potent and selective 5-HT4 partial agonist