GPCR19(G 蛋白偶联受体19)

GPCR19 is a G protein-coupled receptor for bile acid. Activation of this receptor induces its internalization and the production of intreacelluar cAMP. It is Involved in the suppression of macrophage function and regulation of energy homeostasis.

Products for GPCR19

Cat.No. 产品名称 Information
GC46012 DY 268 An FXR antagonist
GC36319 INT-777 R-enantiomer
S-EMCA R enantiomer
INT-777 R-enantiomer 是 INT-77 的 R 型异构体，对 TGR5 的 EC50 值为 4.79 μM，活性比 INT-777 低。
GC40637 BAR501 A selective GP-BAR1 agonist
GC34775 SBI-115
SBI-115是一种G蛋白胆汁酸偶联受体1（TGR5；GPCR19）拮抗剂。
GC33768 Deoxycholic acid sodium salt (Sodium deoxycholate)
脱氧胆酸钠; Sodium deoxycholate
Deoxycholic acid sodium salt (Sodium deoxycholate)是一种胆汁酸，是肠道代谢的副产物，可激活 G 蛋白偶联胆汁酸受体 TGR5。
GC33762 Deoxycholic acid (Cholanoic Acid)
去氧胆酸; Cholanoic Acid; Desoxycholic acid
Deoxycholic acid (Cholanoic Acid)是一种胆汁酸，肠道代谢副产物，可以激活G 蛋白偶联胆汁酸受体TGR5。
GC32742 INT-767 INT-767是法尼醇X受体/TGR5双激动剂，平均EC50分别为30和630nM。
GC31370 SB756050 A TGR5 agonist
GC30565 BAR502 A dual agonist of GP-BAR1 and FXR
GC13681 INT-777
6ALPHA-乙基-23(S)-甲基胆酸,S-EMCA
INT-777 是一种新型特异性半合成 TGR5 激动剂，用于减轻 AD 小鼠模型的心肌细胞损伤，改善认知障碍和突触功能障碍。
GC16363 TGR5 Receptor Agonist
CCDC
A TGR5 agonist
GN10489 Hyodeoxycholic acid
猪去氧胆酸; HDCA
A secondary bile acid