Prostaglandin Receptor(前列腺素受体)

Prostaglandin receptors are a group of g-protein coupled receptor that exhibited a variety of functions in regulation of blood pressure and renal function; smooth muscle contraction; inhibition of plate aggregation; immune response etc.

Products for Prostaglandin Receptor

Cat.No. 产品名称 Information
GC30572 Aganepag (AGN 210937)
AGN 210937
Aganepag (AGN 210937) 是一种有效的 Prostanoid EP2 受体激动剂，EC50 为 0.19 nM，对 EP4 受体没有活性。
GC30561 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 2-(E-2-decenoylamino)ethyl2-(cyclohexylethyl)sulfide是一种由压力诱发的溃疡和低毒性抑制剂，可以在压力引起的溃疡大鼠中，维持磷脂酶A2(phospholipaseA2)和前列腺素E2(prostaglandinE2)的含量水平。
GC30370 Dinoprost (Prostaglandin F2a)
地诺前列素; Prostaglandin F2α; PGF2α
Dinoprost (Prostaglandin F2a)是一种口服有效的强效前列腺素受体（FP 受体）激动剂。Dinoprost刺激子宫肌层活动，放松宫颈，抑制黄体类固醇生成，并通过直接作用诱导黄体溶解。
GC30307 GSK-269984A GSK-269984A是前列腺素E2受体1(ProstaglandinE2Receptor1(EP1))的拮抗剂，pIC50值为7.9。
GC30299 GSK726701A GSK726701A是前列腺素E2受体4(EP4)的部分激动剂，pEC50为7.4。
GC30068 Taprenepag (CP-544326)
CP-544326
A potent EP₂ receptor agonist
GC19395 MK-7246 A CRTH₂/DP₂ receptor antagonist
GC19354 TG6-10-1 A potent EP₂ receptor antagonist
GC19327 Setipiprant
司替匹仑,ACT-129968; KYTH-105
An antagonist of CRTH₂/DP₂
GC19153 Fevipiprant
非韦匹仑,QAW039; NVP-QAW039
A DP₂/CRTH₂ antagonist
GC19147 Evatanepag
2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸,CP-533536 free acid
Evatanepag (CP-533536) 是一种非前列腺素、强效和选择性 EP2 受体激动剂。
GC18678 CAY10595 A potent CRTH2/DP₂ receptor antagonist
GC18318 CAY10441
RO1138452
An IP receptor antagonist
GC16539 Butaprost
布他前列素
A selective agonist for the EP₂ receptors
GC18132 U-44069
9,11-dideoxy-9α,11α-epoxymethano PGF2α,9,11-dideoxy-9α,11α-epoxymethano Prostaglandin F2α,9,11-epoxymethano Prostaglandin H2
A TP receptor agonist
GC13732 TG4-155 A brain penetrant EP₂ antagonist
GC17224 AH 23848 (calcium salt) Dual antagonist of TP and EP₄ receptors
GC10673 E7046
E7046
An EP₄ receptor antagonist
GC14859 BW 246C
8-epi BW 245C
The less active C-8 diastereomer of BW 245C
GC17719 5-trans U-46619
5,6-trans U-46619
An isomer of U-46619
GC13284 CJ-42794
4-[(1S)-1-[[5-氯-2-(4-氟苯氧基)苄基]氨基]乙基]苯甲酸,RQ-00015986
A selective EP₄ receptor antagonist
GC12290 Norgestimate
诺孕酯
A progestin
GC15640 BAY u3405
雷马曲班; BAY u3405
A dual TP and DP₂/CRTH₂ receptor antagonist
GC18111 Seratrodast
塞曲司特; AA 2414
A thromboxane A₂ receptor antagonist
GC14758 BM 567 A dual thromboxane synthase inhibitor/TP receptor antagonist
GC10771 CJ-023423
RQ-00000007
An EP₄ receptor antagonist
GC16800 MF498 A selective EP₄ antagonist
GC16027 ONO-8711
(5Z)-6-[(2R,3S)-3-[[[(4-氯-2-甲基苯基)磺酰基]氨基]甲基]双环[2.2.2]辛-2-基]-5-己烯酸
A potent EP₁ receptor antagonist
GC17348 BW A868C
3-[(2-环己基-2-羟乙基)氨基]-2,5-二氧代-1-(苯甲基)-4-咪唑啶庚酸
A DP receptor antagonist
GC14212 BW 245C A selective DP₁ receptor agonist
GC15213 SQ 29,548
1S-[1Α,2Β(5Z),3Β,4Α]]-7-[3-[2-(苯氨基甲酰基)肼基甲基]-7-氧代双环[2.2.1]庚-2-基]-5-庚烯酸
A selective TP receptor antagonist
GC17410 S18886
特鲁曲班,Terutroban,Triplion
A TP receptor antagonist
GC10623 ACS 67 An H₂S-releasing latanoprost analog
GC16566 AL 8810 isopropyl ester A lipid soluble, esterified prodrug of AL 8810
GC16895 AL 8810 A potent, selective FP receptor antagonist
GC11067 PF 04418948 An orally active, potent, selective EP₂ receptor antagonist
GC15157 SC 51322 A selective EP₁ antagonist
GC14812 GW 627368 A potent EP₄ receptor antagonist
GC13165 SC 51089
CID132748
Selective EP₁ antagonist
GC16639 NS 304
赛乐西帕,NS-304; ACT-293987
An IP receptor agonist prodrug
GC10304 L-798,106
CM9; GW671021
A selective EP₃ receptor antagonist
GC13067 L-655,240 thromboxane A2/prostaglandin endoperoxide receptor antagonist
GC11820 BMY 45778 partial agonist at IP1 prostacyclin receptors
GC14128 SC 19220 A selective EP₁ receptor antagonist
GC13609 L-670,596 thromboxane A2/prostaglandin endoperoxide receptor antagonist
GC12750 (+)-Fluprostenol
曲伏前列素杂质
A potent FP receptor agonist
GC15622 Prostaglandin F2α
地诺前列素氨丁三醇; Prostaglandin F2α tromethamine salt; PGF2α THAM; Prostaglandin F2α THAM
A water soluble derivative of PGF_2α
GC11122 TCS 2510
CAY10598
Agonist of the PGE₂ receptor EP₄
GC11133 16,16-Dimethyl Prostaglandin E2
16,16dimethyl PGE2
derivative of prostaglandin E2
GC17861 Sulprostone
硫前列酮; SHB 286; CP-34089; ZK-57671
Selective EP₃ receptor agonist