5-Lipoxygenase(5-脂氧合酶)

5-lipoxygenase catalyzes oxidation of AA at the 5-position to yield 5-HpETE and is a current target for pharmaceutical intervention in a number of diseases such as asthma, atherosclerosis and several cancers.

Products for 5-Lipoxygenase

Cat.No. 产品名称 Information
GC17951 2-TEDC
(E)-2-(噻吩-2-基)乙基2-氰基-3-(3,4-二羟基苯基)丙烯酸酯
5-, 12-, and 15-lipoxygenase inhibitor
GC12232 BAY-X 1005
BAY X 1005; DG-031
BAY-X 1005 (BAY X 1005; DG-031) 是一种具有口服活性的选择性 5-脂氧合酶活化蛋白 (FLAP) 抑制剂。
GC10709 BW-B 70C
BW-B 70C 是一种有效的、选择性的和具有口服活性的花生四烯酸 5-脂氧合酶抑制剂。
GC14751 Malotilate
马洛替酯; NKK 105
A hepatoprotective agent
GC12277 MK 886
3-[1-(4-氯苄基)-3-叔丁基硫代-5-异丙基吲哚-2-基]-2,2-二甲基丙酸,L 663536
A potent, selective inhibitor of FLAP
GC12205 PD 146176
NSC168807
PD 146176 是一种有效的选择性网织红细胞 15-LOX-1 抑制剂。
GC10451 U-73122
1-[6-[((17Β)-3-雌酮-1,3,5[10]-三烯-17-基)氨基]乙基]-1H-吡咯-2,5-二酮
U-73122是有效的、选择性的磷脂酶C（PLC）抑制剂，IC₅₀值约为1-2.1µM，也可抑制5-脂氧合酶（5-LO）。
GC16014 Zileuton
齐留通; A 64077; Abbott 64077
A reversible inhibitor of 5-lipoxygenase
GC14435 Zileuton sodium
齐留通钠盐; A 64077 sodium; Abbott 64077 sodium
A reversible inhibitor of 5-lipoxygenase
GC15961 β-acetyl-Boswellic Acid
3-乙酰基-BETA-乳香酸,ABA,3-O-acetyl-β-Boswellic acid,β-Boswellic acid acetate
An anti-inflammatory pentacyclic triterpene