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AP-1

Activator protein 1 (AP-1) is a transcription factor that consist of Jun, Fos, ATF and JDP proteins. It is regulated by cytokines, growth factors, stress signals and infections etc. It is involved in cellular proliferation, transformation and apoptosis.

Products for  AP-1

  1. Cat.No. 产品名称 Information
  2. GC74247 (+)-Glaucarubinone (+)-Glaucarubinone是一种强效的AP-1激活蛋白-1抑制剂,EC50值为0.13µM。
  3. GC74013 FOSL1 degrader 1 FOSL1 degrader 1(4)是一种T-5224-PROTAC,能有效降解FOSL1 (AP-1),抑制HNSCC中癌干性基因的表达。
  4. GC71181 Glucocorticoid receptor modulator 1 Glucocorticoid receptor modulator 1是一种口服活性非甾体选择性糖皮质激素受体调节剂,对NF-κB和AP-1的IC50值分别为9 nM和130 nM。
  5. GC72757 SPC 839 SPC 839(化合物10)是一种口服活性的AP-1和NF-kB介导的转录激活抑制剂,IC50为0.008 μM。
  6. GC12810 SR 11302 An inhibitor of retinoid-induced AP-1 signaling
  7. GC72363 Timolumab Timolumab(BTT1023),一种特异性结合VAP-1的重组全人单克隆抗体。

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